Murcko scaffold
Ring system with 5 rings and 32 atoms
8 chemicals on CompoundList share this ring system.
- Rings
- 5
- Scaffold atoms
- 32
- Chemicals
- 8
- With full pages
- 2
Scaffold SMILES
O=c1[nH]cnc2c1ncn2C1CC(O[PH](=O)OCC2CCC(n3cccnc3=O)O2)CO1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
![Murcko scaffold O=c1[nH]cnc2c1ncn2C1CC(O[PH](=O)OCC2CCC(n3cccnc3=O)O2)CO1](/scaffold/UKLBMCIPDHSPFP-UHFFFAOYSA-N/structure.svg)
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 8 of 8 chemicals
Guanylyl-3'-5'-cytidine ammonium salt
CAS 98046-67-4C19H28N9O12P
Guanylyl-(3'->5')-cytidine
CAS 4785-04-0C19H25N8O12P
![[(2R,3S,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] [(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate chemical structure, C19H26N8O13P2, CAS 36786-90-0](/s/IBZPKQZTZXRCKY-WKSZEZMPSA-N.svg)
[(2R,3S,5R)-5-(2-Amino-6-oxo-3H-purin-9-yl)-2-(phosphonooxymethyl)oxolan-3-yl] [(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methyl hydrogen phosphate
CAS 36786-90-0C19H26N8O13P2
2'-Deoxy-2'-fluoroguanylyl-3',5'-cytidine
CAS 138853-61-9C19H24FN8O11P
2'-Deoxyguanylyl-(3'-5')-2'-deoxycytidine
CAS 23405-83-6C19H25N8O10P
Polydeoxyinosinic-polydeoxy-(5-bromocytidylic)acid
CAS 51853-68-0C19H24BrN7O13P2
Poly(dG-Br(5)dC).poly(dG-Br(5)dC)
CAS 99635-24-2C19H24BrN8O10P
![[(2R,3S,5R)-3-{[{[(2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate chemical structure, C19H25N7O13P2, CAS 34639-43-5](/s/KOGGYZSBMCOCER-IDMWBNCISA-N.svg)
[(2R,3S,5R)-3-{[{[(2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3-hydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}-5-(6-oxo-3,6-dihydro-9H-purin-9-yl)oxolan-2-yl]methyl dihydrogen phosphate
CAS 34639-43-5C19H25N7O13P2
Related scaffolds
Same ring framework with different atoms or bond orders
![Scaffold O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cccnc3=O)C2)O1](/scaffold/ZCPBBFQTZKAEGQ-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cccnc3=O)C2)O14 chemicals![Scaffold O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cncnc3=O)C2)O1](/scaffold/GOIYQAQNJQHPBT-UHFFFAOYSA-N/structure.svg)
O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cncnc3=O)C2)O12 chemicalsOCC3CCC(n4cnc5cncnc54)O3)CO2)c(=O)[nH]1](/scaffold/STZQOOSLIPGVQD-UHFFFAOYSA-N/structure.svg)
O=c1ccn(C2CC(O[PH](=O)OCC3CCC(n4cnc5cncnc54)O3)CO2)c(=O)[nH]12 chemicalsOC2COC(n3cnc4cncnc43)C2)O1](/scaffold/BLCINJUBLGHHMR-UHFFFAOYSA-N/structure.svg)
O=c1ncccn1C1CCC(CO[PH](=O)OC2COC(n3cnc4cncnc43)C2)O11 chemicalOC3COC(n4cnc5cncnc54)C3)O2)c(=O)[nH]1](/scaffold/DBWPAFYAVGBJGK-UHFFFAOYSA-N/structure.svg)
O=c1ccn(C2CCC(CO[PH](=O)OC3COC(n4cnc5cncnc54)C3)O2)c(=O)[nH]11 chemicalOCC2CCC(n3cnc4cncnc43)O2)CO1](/scaffold/DUASBUKOKGDEOQ-UHFFFAOYSA-N/structure.svg)
O=c1ncccn1C1CC(O[PH](=O)OCC2CCC(n3cnc4cncnc43)O2)CO11 chemicalOCC3CCC(n4cnc5cncnc54)O3)CO2)c(=O)[nH]1](/scaffold/MSPXTLFQOAXDAB-UHFFFAOYSA-N/structure.svg)
O=c1ccn(C2CC(O[PH](=S)OCC3CCC(n4cnc5cncnc54)O3)CO2)c(=O)[nH]11 chemicalOCC3CCC(n4cnc5cncnc54)O3)O2)c(=O)[nH]1](/scaffold/RINNECMROHNBKA-UHFFFAOYSA-N/structure.svg)
O=c1ccn(C2CCC(O[PH](=O)OCC3CCC(n4cnc5cncnc54)O3)O2)c(=O)[nH]11 chemical