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Murcko scaffold

Ring system with 5 rings and 32 atoms

9 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
32
Chemicals
9
With full pages
4
Scaffold SMILES

O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cccnc3=O)C2)O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]cnc2c1ncn2C1CCC(CO[PH](=O)OC2COC(n3cccnc3=O)C2)O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

[5-(2-Amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate, azane chemical structure, C19H28N9O10P, CAS 77710-57-7
[5-(2-Amino-6-oxo-3H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate, azane
CAS 77710-57-7C19H28N9O10P
[5-(2-Amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate chemical structure, C19H25N8O10P
[5-(2-Amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methyl [5-(4-amino-2-oxopyrimidin-1-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate
C19H25N8O10P
[5-(4-Amino-5-iodo-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate chemical structure, C19H23IN8O12P-, CAS 7224-16-0
[5-(4-Amino-5-iodo-2-oxopyrimidin-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [5-(2-amino-6-oxo-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate
CAS 7224-16-0C19H23IN8O12P-
Cytidylylguanosine chemical structure, C19H25N8O12P, CAS 2382-65-2
Cytidylylguanosine
CAS 2382-65-2C19H25N8O12P
dCpdG chemical structure, C19H25N8O10P, CAS 15178-66-2
dCpdG
CAS 15178-66-2C19H25N8O10P
Poly(dT-dG)n.poly(dC-dA)n chemical structure, C39H54N16O25P4, CAS 27732-52-1
Poly(dT-dG)n.poly(dC-dA)n
CAS 27732-52-1C39H54N16O25P4
Deoxycytidyl-3'-methylphosphonate-5'-deoxyguanidine chemical structure, C20H27N8O9P, CAS 128312-31-2
Deoxycytidyl-3'-methylphosphonate-5'-deoxyguanidine
CAS 128312-31-2C20H27N8O9P
Deoxycytidylyl-(3'-5')-deoxyguanosine chemical structure, C19H25N8O10P
Deoxycytidylyl-(3'-5')-deoxyguanosine
C19H25N8O10P
Guanosine, cytidylyl-(3'.5')-, ammonium salt chemical structure, C19H28N9O12P, CAS 21052-28-8
Guanosine, cytidylyl-(3'.5')-, ammonium salt
CAS 21052-28-8C19H28N9O12P