Murcko scaffold
Ring system with 2 rings and 12 atoms
151 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 151
- With full pages
- 4
Scaffold SMILES
c1ccc(COCC2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 151 chemicals
2-Propanol, 1-(4-((cyclopropylmethoxy)methyl)phenoxy)-3-((1-methylethyl)amino)-
CAS 63659-22-3C17H27NO3
1-((Benzyloxy)methyl)cyclopropanamine
CAS 633333-64-9C11H15NO
![Benzene, [[(2,2-dibromocyclopropyl)methoxy]methyl]- chemical structure, C11H12Br2O, CAS 55027-60-6](/s/CWJFTTWZUCVIAK-UHFFFAOYSA-N.svg)
Benzene, [[(2,2-dibromocyclopropyl)methoxy]methyl]-
CAS 55027-60-6C11H12Br2O
Ethyl (1S,2S)-2-((benzyloxy)methyl)cyclopropane-1-carboxylate
CAS 692778-41-9C14H18O3
![[(1R,2R)-2-[(Benzyloxy)methyl]cyclopropyl]methanol chemical structure, C12H16O2, CAS 142096-80-8](/s/QXASXPPLOQNMOY-RYUDHWBXSA-N.svg)
[(1R,2R)-2-[(Benzyloxy)methyl]cyclopropyl]methanol
CAS 142096-80-8C12H16O2
1-((Benzyloxy)methyl)cyclopropane-1-carbaldehyde
CAS 288401-39-8C12H14O2
(1R,2R)-Ethyl 2-((benzyloxy)methyl)cyclopropanecarboxylate
CAS 561055-26-3C14H18O3
![[({1-[(1E,3S)-6,8-Dimethyl-3-(propan-2-yl)nona-1,6,7-trien-1-yl]cyclopropyl}methoxy)methyl]benzene chemical structure, C25H36O, CAS 288401-45-6](/s/XINZQXGRBFSLOC-XIQMRYHBSA-N.svg)
[({1-[(1E,3S)-6,8-Dimethyl-3-(propan-2-yl)nona-1,6,7-trien-1-yl]cyclopropyl}methoxy)methyl]benzene
CAS 288401-45-6C25H36O
((1S,2R)-2-((Benzyloxy)methyl)cyclopropyl)methanol
CAS 154001-58-8C12H16O2
![(1S,2S)-1-[(Benzyloxy)methyl]-2-ethylcyclopropan-1-amine chemical structure, C13H19NO, CAS 774175-92-7](/s/BWUCMBPEHJHZCB-QWHCGFSZSA-N.svg)
(1S,2S)-1-[(Benzyloxy)methyl]-2-ethylcyclopropan-1-amine
CAS 774175-92-7C13H19NO
![rel-[[[(1R,2R)-2-(1-Methylethenyl)cyclopropyl]methoxy]methyl]benzene chemical structure, C14H18O, CAS 174758-64-6](/s/VANXFQJIDUKDCC-ZIAGYGMSSA-N.svg)
rel-[[[(1R,2R)-2-(1-Methylethenyl)cyclopropyl]methoxy]methyl]benzene
CAS 174758-64-6C14H18O
![Cyclopropanepropanoic acid, 1-methyl-2-[(phenylmethoxy)methyl]-, cis- chemical structure, C15H20O3, CAS 87433-67-8](/s/VTZRPQMMRQECJY-UKRRQHHQSA-N.svg)
Cyclopropanepropanoic acid, 1-methyl-2-[(phenylmethoxy)methyl]-, cis-
CAS 87433-67-8C15H20O3
![[(1R,2S)-2-(Benzyloxymethyl)cyclopropyl]methanol chemical structure, C12H16O2, CAS 142185-62-4](/s/QXASXPPLOQNMOY-NWDGAFQWSA-N.svg)
[(1R,2S)-2-(Benzyloxymethyl)cyclopropyl]methanol
CAS 142185-62-4C12H16O2
![1-[(Benzyloxy)methyl]cyclopropan-1-ol chemical structure, C11H14O2, CAS 920520-61-2](/s/KJNFCWQOZUJVTA-UHFFFAOYSA-N.svg)
1-[(Benzyloxy)methyl]cyclopropan-1-ol
CAS 920520-61-2C11H14O2
![[1-(Bromomethyl)cyclopropyl]methoxymethylbenzene chemical structure, C12H15BrO, CAS 177200-75-8](/s/WCQALNYIIWYVQJ-UHFFFAOYSA-N.svg)
[1-(Bromomethyl)cyclopropyl]methoxymethylbenzene
CAS 177200-75-8C12H15BrO
![{1-[(Benzyloxy)methyl]cyclopropyl}methanol chemical structure, C12H16O2, CAS 177200-76-9](/s/KBGZAPJNEFMKKZ-UHFFFAOYSA-N.svg)
{1-[(Benzyloxy)methyl]cyclopropyl}methanol
CAS 177200-76-9C12H16O2
2-((Benzyloxy)methyl)cyclopropanecarboxylic acid
CAS 848328-57-4C12H14O3
1-((Benzyloxy)methyl)cyclopropanamine hydrochloride
CAS 308266-23-1C11H16ClNO
![4-[(Cyclopropylmethoxy)methyl]aniline chemical structure, C11H15NO, CAS 1019590-33-0](/s/QBIZNZZWYMBYKN-UHFFFAOYSA-N.svg)
4-[(Cyclopropylmethoxy)methyl]aniline
CAS 1019590-33-0C11H15NO
![3-[(Cyclopropylmethoxy)methyl]aniline chemical structure, C11H15NO, CAS 927803-15-4](/s/PVCCSLDMEPEXAG-UHFFFAOYSA-N.svg)
3-[(Cyclopropylmethoxy)methyl]aniline
CAS 927803-15-4C11H15NO
![4-[(Cyclopropylmethoxy)methyl]phenylboronic acid chemical structure, C11H15BO3, CAS 1256358-62-9](/s/GXKALLDBPFOOKG-UHFFFAOYSA-N.svg)
4-[(Cyclopropylmethoxy)methyl]phenylboronic acid
CAS 1256358-62-9C11H15BO3
![1-Bromo-4-[(cyclopropylmethoxy)methyl]benzene chemical structure, C11H13BrO, CAS 1018681-31-6](/s/UIMSMCPIZJYSST-UHFFFAOYSA-N.svg)
1-Bromo-4-[(cyclopropylmethoxy)methyl]benzene
CAS 1018681-31-6C11H13BrO
![3-[(Cyclopropylmethoxy)methyl]-4-fluorobenzoic acid chemical structure, C12H13FO3, CAS 1343367-59-8](/s/TZOUSMITFYIHON-UHFFFAOYSA-N.svg)
3-[(Cyclopropylmethoxy)methyl]-4-fluorobenzoic acid
CAS 1343367-59-8C12H13FO3
N-Boc-1-benzyloxymethyl-cyclopropanesulfonic acid amide
CAS 1108658-29-2C16H23NO5S
- 1-[3-[(Cyclopropylmethoxy)methyl]-5-(1,1-dimethylethyl)phenyl]ethanone1178584-61-6C17H24O2
- 2-((tert-Butoxycarbonyl)amino)-2-(1-(((4-methoxybenzyl)oxy)methyl)cyclopropyl)acetic acid2010161-02-9C19H27NO6
- 2-Amino-2-(1-(((4-methoxybenzyl)oxy)methyl)cyclopropyl)acetic acid873065-92-0C14H19NO4
- (1-(((4-Methoxybenzyl)oxy)methyl)cyclopropyl)methanol738624-86-7C13H18O3
- 1-(((4-Methoxybenzyl)oxy)methyl)cyclopropane-1-carbaldehyde738624-87-8C13H16O3
- 2-(4-Chlorophenyl)-2-(cyclopropylmethoxy)ethan-1-amine1250007-47-6C12H16ClNO
- 1-[2-Bromo-1-(cyclopropylmethoxy)ethyl]-4-methoxybenzene1250014-73-3C13H17BrO2
- (2-Bromo-1-(cyclopropylmethoxy)ethyl)benzene1249581-48-3C12H15BrO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-4-methylbenzene1249731-06-3C13H17BrO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-methylbenzene1251119-73-9C13H17BrO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-fluorobenzene1250823-53-0C12H14BrFO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-chlorobenzene1250556-04-7C12H14BrClO
- 1-Bromo-2-[2-bromo-1-(cyclopropylmethoxy)ethyl]benzene1250642-97-7C12H14Br2O
- 1-[2-Bromo-1-(cyclopropylmethoxy)ethyl]-4-fluorobenzene1250582-99-0C12H14BrFO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-4-chlorobenzene1249987-60-7C12H14BrClO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-3-fluorobenzene1250370-00-3C12H14BrFO
- 1-[2-Bromo-1-(cyclopropylmethoxy)ethyl]-3-chlorobenzene1247550-37-3C12H14BrClO
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-2-methoxybenzene1249073-61-7C13H17BrO2
- 1-Bromo-3-[2-bromo-1-(cyclopropylmethoxy)ethyl]benzene1247162-90-8C12H14Br2O
- 1-(2-Bromo-1-(cyclopropylmethoxy)ethyl)-3-methoxybenzene1249668-82-3C13H17BrO2
- 1-Bromo-4-[2-bromo-1-(cyclopropylmethoxy)ethyl]benzene1250023-33-6C12H14Br2O
- 1-[2-Bromo-1-(cyclopropylmethoxy)ethyl]-3-methylbenzene1248261-28-0C13H17BrO
- (1R,2R)-2-((Benzyloxy)methyl)cyclopropane-1-carboxylic acid561055-27-4C12H14O3
- 1-[(Benzyloxy)methyl]cyclopropane-1-sulfonamide1152322-85-4C11H15NO3S
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)NC1CC116 chemicals
O=C(OCc1ccccc1)C1CC115 chemicals
c1ccc(CNCC2CC2)cc112 chemicals
O=C(Cc1ccccc1)NC1CC19 chemicals
c1ccc(COCC2CO2)cc19 chemicals
O=S(=O)(OCC1CO1)c1ccccc18 chemicals
O=C(NCc1ccccc1)C1CC18 chemicals
O=C(OCC1CO1)c1ccccc18 chemicals
O=C(NCC1CC1)c1ccccc17 chemicals
O=C(CC(=O)C1CC1)c1ccccc15 chemicals
O=C(OCc1ccccc1)C1CO13 chemicals
O=C(OCc1ccccc1)N1CC13 chemicals