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Murcko scaffold

Ring system with 2 rings and 12 atoms

40 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
40
With full pages
8
Scaffold SMILES

c1cnc(C2CCOCC2)nc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1cnc(C2CCOCC2)nc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 40 of 40 chemicals

4-Chloro-2-(tetrahydro-2H-pyran-4-yl)pyrimidine chemical structure, C9H11ClN2O, CAS 1159821-25-6
4-Chloro-2-(tetrahydro-2H-pyran-4-yl)pyrimidine
CAS 1159821-25-6C9H11ClN2O
2-(Tetrahydro-pyran-4-yl)-pyrimidin-4-ylamine chemical structure, C9H13N3O, CAS 1159821-30-3
2-(Tetrahydro-pyran-4-yl)-pyrimidin-4-ylamine
CAS 1159821-30-3C9H13N3O
4,6-Dichloro-2-(oxan-4-yl)pyrimidine chemical structure, C9H10Cl2N2O, CAS 1045861-18-4
4,6-Dichloro-2-(oxan-4-yl)pyrimidine
CAS 1045861-18-4C9H10Cl2N2O
2-(Tetrahydro-2H-pyran-4-yl)pyrimidin-5-amine chemical structure, C9H13N3O, CAS 1248691-42-0
2-(Tetrahydro-2H-pyran-4-yl)pyrimidin-5-amine
CAS 1248691-42-0C9H13N3O
4-Methyl-2-(oxan-4-yl)pyrimidine-5-carboxylic acid chemical structure, C11H14N2O3, CAS 1493751-21-5
4-Methyl-2-(oxan-4-yl)pyrimidine-5-carboxylic acid
CAS 1493751-21-5C11H14N2O3
2-(Tetrahydro-2H-pyran-4-yl)-5-pyrimidineethanamine chemical structure, C11H17N3O, CAS 944905-85-5
2-(Tetrahydro-2H-pyran-4-yl)-5-pyrimidineethanamine
CAS 944905-85-5C11H17N3O
4-Amino-2-(oxan-4-yl)pyrimidine-5-carbonitrile chemical structure, C10H12N4O, CAS 1484489-45-3
4-Amino-2-(oxan-4-yl)pyrimidine-5-carbonitrile
CAS 1484489-45-3C10H12N4O
2-(Oxan-4-yl)pyrimidine-5-carbaldehyde chemical structure, C10H12N2O2, CAS 1484495-55-7
2-(Oxan-4-yl)pyrimidine-5-carbaldehyde
CAS 1484495-55-7C10H12N2O2
4,6-Dimethyl-2-(oxan-4-yl)pyrimidine-5-carboxylic acid chemical structure, C12H16N2O3, CAS 1493143-91-1
4,6-Dimethyl-2-(oxan-4-yl)pyrimidine-5-carboxylic acid
CAS 1493143-91-1C12H16N2O3
2-(Oxan-4-yl)pyrimidine-4-carboxylic acid chemical structure, C10H12N2O3, CAS 1480252-69-4
2-(Oxan-4-yl)pyrimidine-4-carboxylic acid
CAS 1480252-69-4C10H12N2O3
2-(Tetrahydro-2H-pyran-4-yl)pyrimidine-5-carboxylic acid chemical structure, C10H12N2O3, CAS 1447607-07-9
2-(Tetrahydro-2H-pyran-4-yl)pyrimidine-5-carboxylic acid
CAS 1447607-07-9C10H12N2O3
4-Chloro-5-bromo-2-(4-tetrahydropyranyl)pyrimidine chemical structure, C9H10BrClN2O, CAS 1399482-87-1
4-Chloro-5-bromo-2-(4-tetrahydropyranyl)pyrimidine
CAS 1399482-87-1C9H10BrClN2O
Ethyl 2-(tetrahydro-2H-pyran-4-yl)pyrimidine-5-carboxylate chemical structure, C12H16N2O3, CAS 1447607-86-4
Ethyl 2-(tetrahydro-2H-pyran-4-yl)pyrimidine-5-carboxylate
CAS 1447607-86-4C12H16N2O3
2-(2-(Tetrahydro-2H-pyran-4-yl)pyrimidin-5-yl)ethanamine hydrochloride chemical structure, C11H18ClN3O, CAS 1196154-65-0
2-(2-(Tetrahydro-2H-pyran-4-yl)pyrimidin-5-yl)ethanamine hydrochloride
CAS 1196154-65-0C11H18ClN3O
5-Bromo-2-(oxan-4-yl)pyrimidine chemical structure, C9H11BrN2O, CAS 1357580-19-8
5-Bromo-2-(oxan-4-yl)pyrimidine
CAS 1357580-19-8C9H11BrN2O
4-Chloro-2-(oxan-4-yl)pyrimidine-5-carboxylic acid chemical structure, C10H11ClN2O3, CAS 1782847-89-5
4-Chloro-2-(oxan-4-yl)pyrimidine-5-carboxylic acid
CAS 1782847-89-5C10H11ClN2O3
4-(5-Bromopyrimidin-2-yl)oxan-4-ol chemical structure, C9H11BrN2O2, CAS 1459772-37-2
4-(5-Bromopyrimidin-2-yl)oxan-4-ol
CAS 1459772-37-2C9H11BrN2O2
6-Chloro-2-(oxan-4-yl)pyrimidine-4-carboxylic acid chemical structure, C10H11ClN2O3, CAS 1892538-44-1
6-Chloro-2-(oxan-4-yl)pyrimidine-4-carboxylic acid
CAS 1892538-44-1C10H11ClN2O3
tert-Butyl N-[4-(5-bromopyrimidin-2-yl)oxan-4-yl]carbamate chemical structure, C14H20BrN3O3, CAS 2137608-07-0
tert-Butyl N-[4-(5-bromopyrimidin-2-yl)oxan-4-yl]carbamate
CAS 2137608-07-0C14H20BrN3O3
4-(Pyrimidin-2-yl)oxan-4-amine chemical structure, C9H13N3O, CAS 1866002-29-0
4-(Pyrimidin-2-yl)oxan-4-amine
CAS 1866002-29-0C9H13N3O
[2-(Oxan-4-yl)pyrimidin-5-yl]boronic acid chemical structure, C9H13BN2O3, CAS 1899906-14-9
[2-(Oxan-4-yl)pyrimidin-5-yl]boronic acid
CAS 1899906-14-9C9H13BN2O3
4-(Pyrimidin-2-yl)oxane-4-carboxylic acid chemical structure, C10H12N2O3, CAS 1876270-24-4
4-(Pyrimidin-2-yl)oxane-4-carboxylic acid
CAS 1876270-24-4C10H12N2O3
4-(5-Bromopyrimidin-2-yl)oxan-4-amine chemical structure, C9H12BrN3O, CAS 1863033-62-8
4-(5-Bromopyrimidin-2-yl)oxan-4-amine
CAS 1863033-62-8C9H12BrN3O
4-(5-Iodopyrimidin-2-yl)oxan-4-amine chemical structure, C9H12IN3O, CAS 1865175-03-6
4-(5-Iodopyrimidin-2-yl)oxan-4-amine
CAS 1865175-03-6C9H12IN3O