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Murcko scaffold

7-Oxa-4-azaspiro[2.5]octane scaffold

42 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
42
With full pages
8
Scaffold SMILES

C1COCC2(CC2)N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 7-Oxa-4-azaspiro[2.5]octane page
Murcko scaffold C1COCC2(CC2)N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 42 of 42 chemicals

Ethyl 2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetate chemical structure, C10H17NO3, CAS 160415-39-4
Ethyl 2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetate
CAS 160415-39-4C10H17NO3
2-(7-Oxa-4-azaspiro[2.5]octan-4-yl)ethanol chemical structure, C8H15NO2, CAS 1098755-10-2
2-(7-Oxa-4-azaspiro[2.5]octan-4-yl)ethanol
CAS 1098755-10-2C8H15NO2
7-Oxa-4-azaspiro[2.5]octane hydrochloride chemical structure, C6H12ClNO, CAS 218595-22-3
7-Oxa-4-azaspiro[2.5]octane hydrochloride
CAS 218595-22-3C6H12ClNO
7-Oxa-4-azaspiro[2.5]octane chemical structure, C6H11NO, CAS 126616-59-9
7-Oxa-4-azaspiro[2.5]octane
CAS 126616-59-9C6H11NO
2-{7-Oxa-4-azaspiro[2.5]octan-6-yl}acetic acid chemical structure, C8H13NO3, CAS 160415-43-0
2-{7-Oxa-4-azaspiro[2.5]octan-6-yl}acetic acid
CAS 160415-43-0C8H13NO3
2-{7-Oxa-4-azaspiro[2.5]octan-6-yl}acetic acid hydrochloride chemical structure, C8H14ClNO3, CAS 160415-13-4
2-{7-Oxa-4-azaspiro[2.5]octan-6-yl}acetic acid hydrochloride
CAS 160415-13-4C8H14ClNO3
tert-Butyl (6R)-6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate chemical structure, C12H21NO4, CAS 1427175-16-3
tert-Butyl (6R)-6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate
CAS 1427175-16-3C12H21NO4
tert-Butyl (6S)-6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate chemical structure, C12H21NO4, CAS 1980007-42-8
tert-Butyl (6S)-6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate
CAS 1980007-42-8C12H21NO4
2-(7-Oxa-4-azaspiro[2.5]octan-4-yl)ethanamine chemical structure, C8H16N2O, CAS 2045188-88-1
2-(7-Oxa-4-azaspiro[2.5]octan-4-yl)ethanamine
CAS 2045188-88-1C8H16N2O
7-Oxa-4-azaspiro[2.5]octane-1,4-dicarboxylic acid, 4-(1,1-dimethylethyl) ester chemical structure, C12H19NO5, CAS 1251001-96-3
7-Oxa-4-azaspiro[2.5]octane-1,4-dicarboxylic acid, 4-(1,1-dimethylethyl) ester
CAS 1251001-96-3C12H19NO5
tert-Butyl 1-amino-7-oxa-4-azaspiro[2.5]octane-4-carboxylate chemical structure, C11H20N2O3, CAS 1251023-04-7
tert-Butyl 1-amino-7-oxa-4-azaspiro[2.5]octane-4-carboxylate
CAS 1251023-04-7C11H20N2O3
tert-Butyl 6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate chemical structure, C12H21NO4, CAS 1823407-27-7
tert-Butyl 6-(hydroxymethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate
CAS 1823407-27-7C12H21NO4
4-Boc-7-oxa-4-azaspiro[2.5]octane chemical structure, C11H19NO3, CAS 2805275-20-9
4-Boc-7-oxa-4-azaspiro[2.5]octane
CAS 2805275-20-9C11H19NO3
4-[(tert-Butoxy)carbonyl]-7-oxa-4-azaspiro[2.5]octane-6-carboxylic acid chemical structure, C12H19NO5, CAS 2402829-08-5
4-[(tert-Butoxy)carbonyl]-7-oxa-4-azaspiro[2.5]octane-6-carboxylic acid
CAS 2402829-08-5C12H19NO5
Methyl2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetatehydrochloride chemical structure, C9H16ClNO3, CAS 2411238-08-7
Methyl2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetatehydrochloride
CAS 2411238-08-7C9H16ClNO3
Methyl 2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetate chemical structure, C9H15NO3, CAS 2411238-07-6
Methyl 2-{7-oxa-4-azaspiro[2.5]octan-6-yl}acetate
CAS 2411238-07-6C9H15NO3
tert-Butyl 6-(aminomethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate hydrochloride chemical structure, C12H23ClN2O3, CAS 2413876-30-7
tert-Butyl 6-(aminomethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate hydrochloride
CAS 2413876-30-7C12H23ClN2O3
tert-Butyl 6-(aminomethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate chemical structure, C12H22N2O3, CAS 2169126-19-4
tert-Butyl 6-(aminomethyl)-7-oxa-4-azaspiro[2.5]octane-4-carboxylate
CAS 2169126-19-4C12H22N2O3
(7-Oxa-4-azaspiro(2.5)octan-6-yl)methanol chemical structure, C7H13NO2, CAS 2408968-46-5
(7-Oxa-4-azaspiro(2.5)octan-6-yl)methanol
CAS 2408968-46-5C7H13NO2
(6S)-(7-Oxa-4-azaspiro[2.5]octan-6-yl)methanol chemical structure, C7H13NO2, CAS 2832590-71-1
(6S)-(7-Oxa-4-azaspiro[2.5]octan-6-yl)methanol
CAS 2832590-71-1C7H13NO2
(R)-(7-Oxa-4-azaspiro[2.5]octan-6-yl)methanol chemical structure, C7H13NO2, CAS 2681297-97-0
(R)-(7-Oxa-4-azaspiro[2.5]octan-6-yl)methanol
CAS 2681297-97-0C7H13NO2
(S)-4-Boc-7-oxa-4-azaspiro[2.5]octane-6-carboxylic Acid chemical structure, C12H19NO5, CAS 2832308-01-5
(S)-4-Boc-7-oxa-4-azaspiro[2.5]octane-6-carboxylic Acid
CAS 2832308-01-5C12H19NO5
(R)-4-Boc-7-oxa-4-azaspiro[2.5]octane-6-carboxylic Acid chemical structure, C12H19NO5, CAS 2832304-65-9
(R)-4-Boc-7-oxa-4-azaspiro[2.5]octane-6-carboxylic Acid
CAS 2832304-65-9C12H19NO5
7-Oxa-4-azaspiro[2.5]octane-4-carboxamide chemical structure, C7H12N2O2, CAS 2408965-08-0
7-Oxa-4-azaspiro[2.5]octane-4-carboxamide
CAS 2408965-08-0C7H12N2O2