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Murcko scaffold

6-Azaspiro[2.5]octane scaffold

277 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
8
Chemicals
277
With full pages
34
Scaffold SMILES

C1CC2(CCN1)CC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Azaspiro[2.5]octane page
Murcko scaffold C1CC2(CCN1)CC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 277 chemicals

Spirgetine chemical structure, C10H20N4, CAS 144-45-6
Spirgetine
CAS 144-45-6C10H20N4
(2-(6-Azaspiro(2.5)oct-6-yl)ethyl)guanidinium sulphate (2:1) chemical structure, C20H42N8O4S, CAS 1212-79-9
(2-(6-Azaspiro(2.5)oct-6-yl)ethyl)guanidinium sulphate (2:1)
CAS 1212-79-9C20H42N8O4S
tert-Butyl 6-azaspiro[2.5]octan-1-ylcarbamate chemical structure, C12H22N2O2, CAS 147632-34-6
tert-Butyl 6-azaspiro[2.5]octan-1-ylcarbamate
CAS 147632-34-6C12H22N2O2
6-Methyl-6-azaspiro[2.5]octane chemical structure, C8H15N, CAS 2817201-86-6
6-Methyl-6-azaspiro[2.5]octane
CAS 2817201-86-6C8H15N
1,1-Difluoro-6-azaspiro[2.5]octane chemical structure, C7H11F2N, CAS 144230-47-7
1,1-Difluoro-6-azaspiro[2.5]octane
CAS 144230-47-7C7H11F2N
6-Azaspiro[2.5]octan-1-amine chemical structure, C7H14N2, CAS 1780899-45-7
6-Azaspiro[2.5]octan-1-amine
CAS 1780899-45-7C7H14N2
6-Methyl-6-azaspiro[2.5]octan-4-amine chemical structure, C8H16N2, CAS 1368362-41-7
6-Methyl-6-azaspiro[2.5]octan-4-amine
CAS 1368362-41-7C8H16N2
6-Azaspiro[2.5]octane chemical structure, C7H13N, CAS 872-64-0
6-Azaspiro[2.5]octane
CAS 872-64-0C7H13N
tert-Butyl 1-(hydroxymethyl)-6-azaspiro(2.5)octane-6-carboxylate chemical structure, C13H23NO3, CAS 236406-42-1
tert-Butyl 1-(hydroxymethyl)-6-azaspiro(2.5)octane-6-carboxylate
CAS 236406-42-1C13H23NO3
(2S)-6-tert-Butoxycarbonyl-6-azaspiro[2.5]octane-2-carboxylic acid chemical structure, C13H21NO4, CAS 2306247-31-2
(2S)-6-tert-Butoxycarbonyl-6-azaspiro[2.5]octane-2-carboxylic acid
CAS 2306247-31-2C13H21NO4
(R)-6-(tert-Butoxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid chemical structure, C13H21NO4, CAS 1361202-54-1
(R)-6-(tert-Butoxycarbonyl)-6-azaspiro[2.5]octane-1-carboxylic acid
CAS 1361202-54-1C13H21NO4
6-((tert-Butoxy)carbonyl)-6-azaspiro(2.5)octane-1-carboxylic acid chemical structure, C13H21NO4, CAS 871727-05-8
6-((tert-Butoxy)carbonyl)-6-azaspiro(2.5)octane-1-carboxylic acid
CAS 871727-05-8C13H21NO4
(4S)-6-Azaspiro[2.5]octan-4-ol hydrochloride chemical structure, C7H14ClNO, CAS 1103501-89-8
(4S)-6-Azaspiro[2.5]octan-4-ol hydrochloride
CAS 1103501-89-8C7H14ClNO
(4S)-6-Azaspiro[2.5]octan-4-ol chemical structure, C7H13NO, CAS 1103501-90-1
(4S)-6-Azaspiro[2.5]octan-4-ol
CAS 1103501-90-1C7H13NO
tert-Butyl 1-(aminomethyl)-6-azaspiro[2.5]octane-6-carboxylate chemical structure, C13H24N2O2, CAS 1163729-53-0
tert-Butyl 1-(aminomethyl)-6-azaspiro[2.5]octane-6-carboxylate
CAS 1163729-53-0C13H24N2O2
tert-Butyl 1-cyano-6-azaspiro(2.5)octane-6-carboxylate chemical structure, C13H20N2O2, CAS 1174006-82-6
tert-Butyl 1-cyano-6-azaspiro(2.5)octane-6-carboxylate
CAS 1174006-82-6C13H20N2O2
6-tert-Butyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate chemical structure, C15H25NO4, CAS 1242268-17-2
6-tert-Butyl 1-ethyl 6-azaspiro[2.5]octane-1,6-dicarboxylate
CAS 1242268-17-2C15H25NO4
6-Azaspiro[2.5]octane-1-carboxylic acid chemical structure, C8H13NO2, CAS 1242028-68-7
6-Azaspiro[2.5]octane-1-carboxylic acid
CAS 1242028-68-7C8H13NO2
6-Azaspiro[2.5]octane-1-carboxylic acid hydrochloride chemical structure, C8H14ClNO2, CAS 1332530-45-6
6-Azaspiro[2.5]octane-1-carboxylic acid hydrochloride
CAS 1332530-45-6C8H14ClNO2
tert-Butyl 6-azaspiro[2.5]octane-6-carboxylate chemical structure, C12H21NO2, CAS 955028-67-8
tert-Butyl 6-azaspiro[2.5]octane-6-carboxylate
CAS 955028-67-8C12H21NO2
(S)-tert-Butyl 6-azaspiro[2.5]octan-1-ylcarbamate chemical structure, C12H22N2O2, CAS 872983-54-5
(S)-tert-Butyl 6-azaspiro[2.5]octan-1-ylcarbamate
CAS 872983-54-5C12H22N2O2
6-Azaspiro(2.5)octane hydrochloride chemical structure, C7H14ClN, CAS 1037834-62-0
6-Azaspiro(2.5)octane hydrochloride
CAS 1037834-62-0C7H14ClN
Methyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride chemical structure, C9H16ClNO2, CAS 874365-30-7
Methyl 6-azaspiro[2.5]octane-1-carboxylate hydrochloride
CAS 874365-30-7C9H16ClNO2
Methyl 6-azaspiro[2.5]octane-1-carboxylate chemical structure, C9H15NO2, CAS 874440-82-1
Methyl 6-azaspiro[2.5]octane-1-carboxylate
CAS 874440-82-1C9H15NO2