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Murcko scaffold

Aza-THIP scaffold

27 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
27
With full pages
3
Scaffold SMILES

O=c1[nH][nH]c2c1CCNC2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Aza-THIP page
Murcko scaffold O=c1[nH][nH]c2c1CCNC2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 27 of 27 chemicals

2-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3(2H)-one chemical structure, C7H11N3O, CAS 1215484-46-0
2-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-3(2H)-one
CAS 1215484-46-0C7H11N3O
1-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C7H11N3O, CAS 71233-24-4
1-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 71233-24-4C7H11N3O
Aza-THIP chemical structure, C6H9N3O, CAS 654666-65-6
Aza-THIP
CAS 654666-65-6C6H9N3O
3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-5-carboxylic acid hydrochloride chemical structure, C7H9N3O3, CAS 1258637-47-6
3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine-5-carboxylic acid hydrochloride
CAS 1258637-47-6C7H9N3O3
4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]pyridin-3(2H)-one hydrochloride chemical structure, C6H10ClN3O, CAS 1187830-91-6
4,5,6,7-Tetrahydro-1H-pyrazolo[3,4-c]pyridin-3(2H)-one hydrochloride
CAS 1187830-91-6C6H10ClN3O
tert-Butyl 2-methyl-3-oxo-1,2,3,4,5,7-hexahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate chemical structure, C12H19N3O3, CAS 1215230-05-9
tert-Butyl 2-methyl-3-oxo-1,2,3,4,5,7-hexahydro-6H-pyrazolo[3,4-c]pyridine-6-carboxylate
CAS 1215230-05-9C12H19N3O3
3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo-[3,4-c]pyridine-5-carboxylic acid hydrochloride chemical structure, C7H10ClN3O3, CAS 1313739-01-3
3-Hydroxy-4,5,6,7-tetrahydro-2H-pyrazolo-[3,4-c]pyridine-5-carboxylic acid hydrochloride
CAS 1313739-01-3C7H10ClN3O3
1H,2H,3H,4H,5H,6H,7H-Pyrazolo[3,4-c]pyridin-3-one dihydrochloride chemical structure, C6H11Cl2N3O, CAS 1384431-32-6
1H,2H,3H,4H,5H,6H,7H-Pyrazolo[3,4-c]pyridin-3-one dihydrochloride
CAS 1384431-32-6C6H11Cl2N3O
7-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C7H11N3O, CAS 1554004-51-1
7-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 1554004-51-1C7H11N3O
7,7-Dimethyl-1H,2H,3H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-one chemical structure, C8H13N3O, CAS 1551304-78-9
7,7-Dimethyl-1H,2H,3H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-one
CAS 1551304-78-9C8H13N3O
tert-Butyl 3-hydroxy-2H,4H,5H,6H,7H-pyrazolo(3,4-c)pyridine-6-carboxylate chemical structure, C11H17N3O3, CAS 152559-31-4
tert-Butyl 3-hydroxy-2H,4H,5H,6H,7H-pyrazolo(3,4-c)pyridine-6-carboxylate
CAS 152559-31-4C11H17N3O3
tert-Butyl 3-hydroxy-1-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-6-carboxylate chemical structure, C12H19N3O3, CAS 1780348-99-3
tert-Butyl 3-hydroxy-1-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-6-carboxylate
CAS 1780348-99-3C12H19N3O3
1-(Propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C9H15N3O, CAS 1550771-61-3
1-(Propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 1550771-61-3C9H15N3O
2-Ethyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C8H13N3O, CAS 1708079-33-7
2-Ethyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridin-3-ol
CAS 1708079-33-7C8H13N3O
1-Ethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C8H13N3O, CAS 1781106-10-2
1-Ethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 1781106-10-2C8H13N3O
1,4-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C8H13N3O, CAS 2060062-01-1
1,4-Dimethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060062-01-1C8H13N3O
1-Ethyl-4-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C9H15N3O, CAS 2060044-11-1
1-Ethyl-4-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060044-11-1C9H15N3O
4-Methyl-1-(propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C10H17N3O, CAS 2060038-72-2
4-Methyl-1-(propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060038-72-2C10H17N3O
1-(Butan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C10H17N3O, CAS 2059974-49-9
1-(Butan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2059974-49-9C10H17N3O
5-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C7H11N3O, CAS 2060057-96-5
5-Methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060057-96-5C7H11N3O
4-Amino-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C6H10N4O, CAS 2059974-40-0
4-Amino-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2059974-40-0C6H10N4O
4-Amino-1-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C7H12N4O, CAS 2060021-23-8
4-Amino-1-methyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060021-23-8C7H12N4O
4-Amino-1-ethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C8H14N4O, CAS 2060051-62-7
4-Amino-1-ethyl-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060051-62-7C8H14N4O
4-Amino-1-(propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol chemical structure, C9H16N4O, CAS 2060026-41-5
4-Amino-1-(propan-2-yl)-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridin-3-ol
CAS 2060026-41-5C9H16N4O