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Murcko scaffold

4H-1,4-Benzoxazine-4-acetamide, 2,3-dihydro-3-oxo-N-(2-thienylmethyl)- scaffold

5 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
5
With full pages
4
Scaffold SMILES

O=C(CN1C(=O)COc2ccccc21)NCc1cccs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 4H-1,4-Benzoxazine-4-acetamide, 2,3-dihydro-3-oxo-N-(2-thienylmethyl)- page
Murcko scaffold O=C(CN1C(=O)COc2ccccc21)NCc1cccs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 5 of 5 chemicals

2-(2-Methyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)acetamide chemical structure, C16H16N2O3S, CAS 606118-84-7
2-(2-Methyl-3-oxo-1,4-benzoxazin-4-yl)-N-(thiophen-2-ylmethyl)acetamide
CAS 606118-84-7C16H16N2O3S
4H-1,4-Benzoxazine-4-acetamide, 2,3-dihydro-3-oxo-N-(2-thienylmethyl)- chemical structure, C15H14N2O3S, CAS 606118-33-6
4H-1,4-Benzoxazine-4-acetamide, 2,3-dihydro-3-oxo-N-(2-thienylmethyl)-
CAS 606118-33-6C15H14N2O3S
4H-1,4-Benzoxazine-4-acetamide, 2-ethyl-2,3-dihydro-3-oxo-N-(2-thienylmethyl)- chemical structure, C17H18N2O3S, CAS 606119-30-6
4H-1,4-Benzoxazine-4-acetamide, 2-ethyl-2,3-dihydro-3-oxo-N-(2-thienylmethyl)-
CAS 606119-30-6C17H18N2O3S
2-(2-Ethyl-6-methyl-3-oxo(2H-benzo[e]1,4-oxazaperhydroin-4-yl))-N-(2-thienylme thyl)acetamide chemical structure, C18H20N2O3S, CAS 606120-33-6
2-(2-Ethyl-6-methyl-3-oxo(2H-benzo[e]1,4-oxazaperhydroin-4-yl))-N-(2-thienylme thyl)acetamide
CAS 606120-33-6C18H20N2O3S
2-(2,6-Dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-N-thiophen-2-ylmethyl-acetamide chemical structure, C17H18N2O3S, CAS 606120-09-6
2-(2,6-Dimethyl-3-oxo-2,3-dihydro-benzo[1,4]oxazin-4-yl)-N-thiophen-2-ylmethyl-acetamide
CAS 606120-09-6C17H18N2O3S