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Murcko scaffold

Ring system with 4 rings and 21 atoms

13 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
13
With full pages
3
Scaffold SMILES

c1ccc(-c2nn3cccnc3c2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2nn3cccnc3c2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

5-Methyl-2,3-diphenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine chemical structure, C20H14F3N3, CAS 698994-01-3
5-Methyl-2,3-diphenyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine
CAS 698994-01-3C20H14F3N3
Ethyl (5,7-dimethyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-6-yl)acetate chemical structure, C24H23N3O2, CAS 432530-77-3
Ethyl (5,7-dimethyl-2,3-diphenylpyrazolo[1,5-a]pyrimidin-6-yl)acetate
CAS 432530-77-3C24H23N3O2
RefChem:381811 chemical structure, C20H17N3, CAS 433239-86-2
RefChem:381811
CAS 433239-86-2C20H17N3
Ethyl 7-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidine-6-carboxylate chemical structure, C22H19N3O2, CAS 433236-33-0
Ethyl 7-methyl-2,3-diphenylpyrazolo[1,5-a]pyrimidine-6-carboxylate
CAS 433236-33-0C22H19N3O2
Phtpp chemical structure, C20H11F6N3O, CAS 805239-56-9
Phtpp
CAS 805239-56-9C20H11F6N3O
3-(4-Methoxyphenyl)-2-phenyl-5,7-bis(trifluoromethyl)-pyrazolo[1,5-a]pyrimidine chemical structure, C21H13F6N3O, CAS 805239-15-0
3-(4-Methoxyphenyl)-2-phenyl-5,7-bis(trifluoromethyl)-pyrazolo[1,5-a]pyrimidine
CAS 805239-15-0C21H13F6N3O
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid chemical structure, C19H13N3O2, CAS 1221724-32-8
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid
CAS 1221724-32-8C19H13N3O2
2,3-Diphenylpyrazolo[1,5-a]pyrimidin-6-amine chemical structure, C18H14N4, CAS 1221723-75-6
2,3-Diphenylpyrazolo[1,5-a]pyrimidin-6-amine
CAS 1221723-75-6C18H14N4
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile chemical structure, C19H12N4, CAS 1221725-35-4
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carbonitrile
CAS 1221725-35-4C19H12N4
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carbaldehyde chemical structure, C19H13N3O, CAS 1235439-22-1
2,3-Diphenylpyrazolo[1,5-a]pyrimidine-6-carbaldehyde
CAS 1235439-22-1C19H13N3O
6-Bromo-2,3-diphenylpyrazolo[1,5-a]pyrimidine chemical structure, C18H12BrN3, CAS 1221724-74-8
6-Bromo-2,3-diphenylpyrazolo[1,5-a]pyrimidine
CAS 1221724-74-8C18H12BrN3
4,4'-(5,7-Bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2,3-diyl)diphenol chemical structure, C20H11F6N3O2, CAS 805239-57-0
4,4'-(5,7-Bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2,3-diyl)diphenol
CAS 805239-57-0C20H11F6N3O2
4-[6-Hydroxy-3-(4-hydroxyphenyl)pyrazolo[1,5-a]pyrimidin-2(1H)-ylidene]cyclohexa-2,5-dien-1-one chemical structure, C18H13N3O3, CAS 924907-75-5
4-[6-Hydroxy-3-(4-hydroxyphenyl)pyrazolo[1,5-a]pyrimidin-2(1H)-ylidene]cyclohexa-2,5-dien-1-one
CAS 924907-75-5C18H13N3O3