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Murcko scaffold

1,2-Diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one scaffold

53 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
53
With full pages
4
Scaffold SMILES

O=C1CCCc2c1cc(-c1ccccc1)n2-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,2-Diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one page
Murcko scaffold O=C1CCCc2c1cc(-c1ccccc1)n2-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 53 chemicals

2-(4-Methoxyphenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C21H19NO2, CAS 76410-25-8
2-(4-Methoxyphenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 76410-25-8C21H19NO2
3-(4-Oxo-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid chemical structure, C21H17NO3, CAS 405921-88-2
3-(4-Oxo-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid
CAS 405921-88-2C21H17NO3
2-(4-Oxo-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid chemical structure, C21H17NO3, CAS 315240-36-9
2-(4-Oxo-2-phenyl-4,5,6,7-tetrahydro-1H-indol-1-yl)benzoic acid
CAS 315240-36-9C21H17NO3
1-(4-Chlorophenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C22H20ClNO, CAS 96757-22-1
1-(4-Chlorophenyl)-6,6-dimethyl-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 96757-22-1C22H20ClNO
1-(4-Hydroxyphenyl)-2-phenyl-5,6,7-trihydroindol-4-one chemical structure, C20H17NO2, CAS 385786-09-4
1-(4-Hydroxyphenyl)-2-phenyl-5,6,7-trihydroindol-4-one
CAS 385786-09-4C20H17NO2
2-(4-Bromophenyl)-1-(2-fluorophenyl)-6,6-dimethyl-5,7-dihydroindol-4-one chemical structure, C22H19BrFNO, CAS 312632-71-6
2-(4-Bromophenyl)-1-(2-fluorophenyl)-6,6-dimethyl-5,7-dihydroindol-4-one
CAS 312632-71-6C22H19BrFNO
2-(4-Bromophenyl)-1-(4-fluorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C22H19BrFNO, CAS 96757-24-3
2-(4-Bromophenyl)-1-(4-fluorophenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 96757-24-3C22H19BrFNO
2-Phenyl-1-[3-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one chemical structure, C21H16F3NO, CAS 325992-48-1
2-Phenyl-1-[3-(trifluoromethyl)phenyl]-4,5,6,7-tetrahydro-1H-indol-4-one
CAS 325992-48-1C21H16F3NO
6,6-Dimethyl-1,2-diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C22H21NO, CAS 68638-85-7
6,6-Dimethyl-1,2-diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 68638-85-7C22H21NO
1-(4-Methylphenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C21H19NO, CAS 83558-06-9
1-(4-Methylphenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 83558-06-9C21H19NO
2-(2-Chlorophenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C20H16ClNO, CAS 251097-84-4
2-(2-Chlorophenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 251097-84-4C20H16ClNO
1-(4-Methoxyphenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C21H19NO2, CAS 51495-00-2
1-(4-Methoxyphenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 51495-00-2C21H19NO2
2-(4-Bromophenyl)-1-(2,4-dimethylphenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C24H24BrNO, CAS 328266-71-3
2-(4-Bromophenyl)-1-(2,4-dimethylphenyl)-6,6-dimethyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 328266-71-3C24H24BrNO
2-(3-Bromophenyl)-6,6-dimethyl-1-(3-nitrophenyl)-5,7-dihydroindol-4-one chemical structure, C22H19BrN2O3, CAS 1022403-88-8
2-(3-Bromophenyl)-6,6-dimethyl-1-(3-nitrophenyl)-5,7-dihydroindol-4-one
CAS 1022403-88-8C22H19BrN2O3
1,2-Diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C20H17NO, CAS 14073-27-9
1,2-Diphenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 14073-27-9C20H17NO
1-(4-Chlorophenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C20H16ClNO, CAS 338979-36-5
1-(4-Chlorophenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 338979-36-5C20H16ClNO
1-(3,4-Dimethoxyphenyl)-6-methyl-2-(4-methylphenyl)-5,6,7-trihydroindol-4-one chemical structure, C24H25NO3, CAS 1119392-10-7
1-(3,4-Dimethoxyphenyl)-6-methyl-2-(4-methylphenyl)-5,6,7-trihydroindol-4-one
CAS 1119392-10-7C24H25NO3
4-[2-(4-Bromophenyl)-6,6-dimethyl-4-oxo-5,7-dihydroindol-1-yl]benzamide chemical structure, C23H21BrN2O2, CAS 1022288-07-8
4-[2-(4-Bromophenyl)-6,6-dimethyl-4-oxo-5,7-dihydroindol-1-yl]benzamide
CAS 1022288-07-8C23H21BrN2O2
2-(4-Bromophenyl)-1-(4-chlorophenyl)-6,6-dimethyl-5,7-dihydroindol-4-one chemical structure, C22H19BrClNO, CAS 902469-90-3
2-(4-Bromophenyl)-1-(4-chlorophenyl)-6,6-dimethyl-5,7-dihydroindol-4-one
CAS 902469-90-3C22H19BrClNO
2-(4-Chlorophenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C20H16ClNO, CAS 14073-28-0
2-(4-Chlorophenyl)-1-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 14073-28-0C20H16ClNO
1-(4-Fluorophenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one chemical structure, C20H16FNO, CAS 96757-16-3
1-(4-Fluorophenyl)-2-phenyl-1,5,6,7-tetrahydro-4H-indol-4-one
CAS 96757-16-3C20H16FNO
2-(3-Bromophenyl)-6,6-dimethyl-1-(4-propan-2-ylphenyl)-5,7-dihydroindol-4-one chemical structure, C25H26BrNO, CAS 1023426-41-6
2-(3-Bromophenyl)-6,6-dimethyl-1-(4-propan-2-ylphenyl)-5,7-dihydroindol-4-one
CAS 1023426-41-6C25H26BrNO
2-(4-Bromophenyl)-6,6-dimethyl-1-(4-sulfanylphenyl)-5,7-dihydroindol-4-one chemical structure, C22H20BrNOS, CAS 1023468-49-6
2-(4-Bromophenyl)-6,6-dimethyl-1-(4-sulfanylphenyl)-5,7-dihydroindol-4-one
CAS 1023468-49-6C22H20BrNOS
1-(4-Acetylphenyl)-2-(4-tert-butylphenyl)-6,6-dimethyl-5,7-dihydroindol-4-one chemical structure, C28H31NO2, CAS 1023510-34-0
1-(4-Acetylphenyl)-2-(4-tert-butylphenyl)-6,6-dimethyl-5,7-dihydroindol-4-one
CAS 1023510-34-0C28H31NO2