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Murcko scaffold

Ring system with 2 rings and 8 atoms

75 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 8
Chemicals: 75
With full pages: 16

Scaffold SMILES

c1cn2ncsc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold

Murcko scaffold c1cn2ncsc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 75 chemicals

6-Chloro-2-methylimidazo[2,1-b][1,3,4]thiadiazole chemical structure, C5H4ClN3S, CAS 189116-10-7

6-Chloro-2-methylimidazo[2,1-b][1,3,4]thiadiazole

CAS 189116-10-7C₅H₄ClN₃S

6-Chloro-2-methyl-5-nitroimidazo[2,1-b][1,3,4]thiadiazole chemical structure, C5H3ClN4O2S, CAS 256348-40-0

6-Chloro-2-methyl-5-nitroimidazo[2,1-b][1,3,4]thiadiazole

CAS 256348-40-0C₅H₃ClN₄O₂S

6-tert-Butyl-2-ethylimidazo[2,1-b][1,3,4]thiadiazole chemical structure, C10H15N3S, CAS 219767-11-0

6-tert-Butyl-2-ethylimidazo[2,1-b][1,3,4]thiadiazole

CAS 219767-11-0C₁₀H₁₅N₃S

6-Methylimidazo(2,1-b)(1,3,4)thiadiazole chemical structure, C5H5N3S, CAS 37654-77-6

6-Methylimidazo(2,1-b)(1,3,4)thiadiazole

CAS 37654-77-6C₅H₅N₃S

Ethyl 2,6-dimethylimidazo[2,1-b][1,3,4]thiadiazole-5-carboxylate chemical structure, C9H11N3O2S, CAS 96356-15-9

Ethyl 2,6-dimethylimidazo[2,1-b][1,3,4]thiadiazole-5-carboxylate

CAS 96356-15-9C₉H₁₁N₃O₂S

2,6-Dimethylimidazo(2,1-b)-1,3,4-thiadiazole-5-methanol chemical structure, C7H9N3OS, CAS 294179-26-3

2,6-Dimethylimidazo(2,1-b)-1,3,4-thiadiazole-5-methanol

CAS 294179-26-3C₇H₉N₃OS

2,6-Dimethylimidazo(2,1-b)(1,3,4)thiadiazole-5-carbaldehyde chemical structure, C7H7N3OS, CAS 294179-25-2

2,6-Dimethylimidazo(2,1-b)(1,3,4)thiadiazole-5-carbaldehyde

CAS 294179-25-2C₇H₇N₃OS

Ethyl 2-ethylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate chemical structure, C9H11N3O2S, CAS 96356-07-9

Ethyl 2-ethylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate

CAS 96356-07-9C₉H₁₁N₃O₂S

Ethyl imidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate chemical structure, C7H7N3O2S, CAS 96356-04-6

Ethyl imidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate

CAS 96356-04-6C₇H₇N₃O₂S

Ethyl 2-methylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate chemical structure, C8H9N3O2S, CAS 96356-05-7

Ethyl 2-methylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylate

CAS 96356-05-7C₈H₉N₃O₂S

2-Methylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylic acid chemical structure, C6H5N3O2S, CAS 96356-06-8

2-Methylimidazo[2,1-b][1,3,4]thiadiazole-6-carboxylic acid

CAS 96356-06-8C₆H₅N₃O₂S

2-Ethylimidazo(2,1-B)(1,3,4)thiadiazole-6-carboxylic acid chemical structure, C7H7N3O2S, CAS 96356-08-0

2-Ethylimidazo(2,1-B)(1,3,4)thiadiazole-6-carboxylic acid

CAS 96356-08-0C₇H₇N₃O₂S

Ethyl imidazo[2,1-b]-1,3,4-thiadiazole-6-acetate chemical structure, C8H9N3O2S, CAS 96356-09-1

Ethyl imidazo[2,1-b]-1,3,4-thiadiazole-6-acetate

CAS 96356-09-1C₈H₉N₃O₂S

Ethyl 2-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)acetate chemical structure, C9H11N3O2S, CAS 96356-11-5

Ethyl 2-(2-methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)acetate

CAS 96356-11-5C₉H₁₁N₃O₂S

Ethyl 2-ethylimidazo[2,1-b]-1,3,4-thiadiazole-6-acetate chemical structure, C10H13N3O2S, CAS 96356-13-7

Ethyl 2-ethylimidazo[2,1-b]-1,3,4-thiadiazole-6-acetate

CAS 96356-13-7C₁₀H₁₃N₃O₂S

2-(2-Methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)acetic acid chemical structure, C7H7N3O2S, CAS 96356-12-6

2-(2-Methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)acetic acid

CAS 96356-12-6C₇H₇N₃O₂S

2,6-Dimethylimidazo[2,1-b][1,3,4]thiadiazole-5-carboxylic acid chemical structure, C7H7N3O2S, CAS 96356-16-0

2,6-Dimethylimidazo[2,1-b][1,3,4]thiadiazole-5-carboxylic acid

CAS 96356-16-0C₇H₇N₃O₂S

2-Bromo-6-methylimidazo[2,1-b][1,3,4]thiadiazole chemical structure, C5H4BrN3S, CAS 230637-04-4

2-Bromo-6-methylimidazo[2,1-b][1,3,4]thiadiazole

CAS 230637-04-4C₅H₄BrN₃S

2-Bromo-6-tert-butylimidazo[2,1-b][1,3,4]thiadiazole chemical structure, C8H10BrN3S, CAS 929975-84-8

2-Bromo-6-tert-butylimidazo[2,1-b][1,3,4]thiadiazole

CAS 929975-84-8C₈H₁₀BrN₃S

Imidazo[2,1-b][1,3,4]thiadiazol-6-amine chemical structure, C4H4N4S, CAS 863203-54-7

Imidazo[2,1-b][1,3,4]thiadiazol-6-amine

CAS 863203-54-7C₄H₄N₄S

(2-Methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)methanamine chemical structure, C6H8N4S, CAS 933734-68-0

(2-Methylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)methanamine

CAS 933734-68-0C₆H₈N₄S

(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)methanamine chemical structure, C7H10N4S, CAS 1177482-04-0

(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)methanamine

CAS 1177482-04-0C₇H₁₀N₄S

2-(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)ethanamine dihydrochloride chemical structure, C8H12N4S, CAS 1018663-66-5

2-(2-Ethylimidazo[2,1-b][1,3,4]thiadiazol-6-yl)ethanamine dihydrochloride

CAS 1018663-66-5C₈H₁₂N₄S

Imidazo[2,1-b][1,3,4]thiadiazole-6-carboxylic acid chemical structure, C5H3N3O2S, CAS 933760-01-1

Imidazo[2,1-b][1,3,4]thiadiazole-6-carboxylic acid

CAS 933760-01-1C₅H₃N₃O₂S