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Murcko scaffold

Ring system with 3 rings and 17 atoms

96 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
96
With full pages
14
Scaffold SMILES

c1ccc(-c2ncnn2-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(-c2ncnn2-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 96 chemicals

Flupoxam chemical structure, C19H14ClF5N4O2, CAS 119126-15-7
Flupoxam
CAS 119126-15-7C19H14ClF5N4O2
Diphenyl-1H-1,2,4-triazole-3-carboxylic acid chemical structure, C15H11N3O2, CAS 24058-92-2
Diphenyl-1H-1,2,4-triazole-3-carboxylic acid
CAS 24058-92-2C15H11N3O2
5-(3-Bromophenyl)-1-(3-chloro-4-methylphenyl)-1,2,4-triazole chemical structure, C15H11BrClN3, CAS 5789-75-3
5-(3-Bromophenyl)-1-(3-chloro-4-methylphenyl)-1,2,4-triazole
CAS 5789-75-3C15H11BrClN3
1-(3-Chloro-4-methylphenyl)-5-(2-chlorophenyl)-1H-1,2,4-triazole chemical structure, C15H11Cl2N3, CAS 5789-63-9
1-(3-Chloro-4-methylphenyl)-5-(2-chlorophenyl)-1H-1,2,4-triazole
CAS 5789-63-9C15H11Cl2N3
1-(4-Chlorophenyl)-5-(4-ethoxyphenyl)-1H-1,2,4-triazole chemical structure, C16H14ClN3O, CAS 416881-08-8
1-(4-Chlorophenyl)-5-(4-ethoxyphenyl)-1H-1,2,4-triazole
CAS 416881-08-8C16H14ClN3O
2-(1-Phenyl-3-propyl-1H-1,2,4-triazol-5-yl)phenol chemical structure, C17H17N3O, CAS 5926-44-3
2-(1-Phenyl-3-propyl-1H-1,2,4-triazol-5-yl)phenol
CAS 5926-44-3C17H17N3O
2-(3-Ethyl-1-phenyl-1H-1,2,4-triazol-5-yl)phenol chemical structure, C16H15N3O, CAS 120029-39-2
2-(3-Ethyl-1-phenyl-1H-1,2,4-triazol-5-yl)phenol
CAS 120029-39-2C16H15N3O
5-Phenyl-1-(p-tolyl)-1H-1,2,4-triazole-3-carboxylic acid chemical structure, C16H13N3O2, CAS 94066-24-7
5-Phenyl-1-(p-tolyl)-1H-1,2,4-triazole-3-carboxylic acid
CAS 94066-24-7C16H13N3O2
1-(4-Methoxyphenyl)-5-phenyl-1H-1,2,4-triazole-3-carboxylic acid chemical structure, C16H13N3O3, CAS 94206-16-3
1-(4-Methoxyphenyl)-5-phenyl-1H-1,2,4-triazole-3-carboxylic acid
CAS 94206-16-3C16H13N3O3
5-(4-Bromophenyl)-1-(2-chloro-4-nitrophenyl)-1H-1,2,4-triazole chemical structure, C14H8BrClN4O2, CAS 6034-24-8
5-(4-Bromophenyl)-1-(2-chloro-4-nitrophenyl)-1H-1,2,4-triazole
CAS 6034-24-8C14H8BrClN4O2
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-phenyl-1H-1,2,4-triazole chemical structure, C18H13F6N3O2, CAS 400079-89-2
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-phenyl-1H-1,2,4-triazole
CAS 400079-89-2C18H13F6N3O2
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-(4-methylphenyl)-1H-1,2,4-triazole chemical structure, C19H15F6N3O2, CAS 400081-38-1
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-(4-methylphenyl)-1H-1,2,4-triazole
CAS 400081-38-1C19H15F6N3O2
5-(4-Bromophenyl)-1-(4-chloro-3-nitrophenyl)-1H-1,2,4-triazole chemical structure, C14H8BrClN4O2, CAS 6039-88-9
5-(4-Bromophenyl)-1-(4-chloro-3-nitrophenyl)-1H-1,2,4-triazole
CAS 6039-88-9C14H8BrClN4O2
2-(3-Methyl-1-phenyl-1H-1,2,4-triazol-5-yl)phenol chemical structure, C15H13N3O, CAS 65483-96-7
2-(3-Methyl-1-phenyl-1H-1,2,4-triazol-5-yl)phenol
CAS 65483-96-7C15H13N3O
5-Phenyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylic acid chemical structure, C16H10F3N3O2, CAS 554436-93-0
5-Phenyl-1-(3-(trifluoromethyl)phenyl)-1H-1,2,4-triazole-3-carboxylic acid
CAS 554436-93-0C16H10F3N3O2
Diphenyl-1H-1,2,4-triazole-3-carbohydrazide chemical structure, C15H13N5O, CAS 92555-70-9
Diphenyl-1H-1,2,4-triazole-3-carbohydrazide
CAS 92555-70-9C15H13N5O
1-(4-Bromo-2-fluorophenyl)-5-(4-nitrophenyl)-1,2,4-triazole chemical structure, C14H8BrFN4O2, CAS 5474-07-7
1-(4-Bromo-2-fluorophenyl)-5-(4-nitrophenyl)-1,2,4-triazole
CAS 5474-07-7C14H8BrFN4O2
1-(2-Chlorophenyl)-5-(4-chlorophenyl)-1,2,4-triazole chemical structure, C14H9Cl2N3, CAS 5790-13-6
1-(2-Chlorophenyl)-5-(4-chlorophenyl)-1,2,4-triazole
CAS 5790-13-6C14H9Cl2N3
1H-1,2,4-Triazole, 1,5-bis(4-chlorophenyl)-3-(methylthio)- chemical structure, C15H11Cl2N3S, CAS 99793-38-1
1H-1,2,4-Triazole, 1,5-bis(4-chlorophenyl)-3-(methylthio)-
CAS 99793-38-1C15H11Cl2N3S
1H-1,2,4-Triazole, 1-(4-chlorophenyl)-5-(4-fluorophenyl)-3-(methylsulfonyl)- chemical structure, C15H11ClFN3O2S, CAS 99793-75-6
1H-1,2,4-Triazole, 1-(4-chlorophenyl)-5-(4-fluorophenyl)-3-(methylsulfonyl)-
CAS 99793-75-6C15H11ClFN3O2S
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-(4-fluorophenyl)-1H-1,2,4-triazole chemical structure, C18H12F7N3O2, CAS 400081-40-5
5-[2,5-Bis(2,2,2-trifluoroethoxy)phenyl]-1-(4-fluorophenyl)-1H-1,2,4-triazole
CAS 400081-40-5C18H12F7N3O2
1-(4-Methoxyphenyl)-N,N-dimethyl-5-phenyl-1,2,4-triazole-3-carboxamide chemical structure, C18H18N4O2, CAS 879050-76-7
1-(4-Methoxyphenyl)-N,N-dimethyl-5-phenyl-1,2,4-triazole-3-carboxamide
CAS 879050-76-7C18H18N4O2
1-(4-Methoxyphenyl)-5-phenyl-1,2,4-triazole-3-carboxamide chemical structure, C16H14N4O2, CAS 85232-40-2
1-(4-Methoxyphenyl)-5-phenyl-1,2,4-triazole-3-carboxamide
CAS 85232-40-2C16H14N4O2
Asp-6537 chemical structure, C17H17N3O3, CAS 524699-72-7
Asp-6537
CAS 524699-72-7C17H17N3O3