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Murcko scaffold

4-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one scaffold

178 chemicals on CompoundList share this ring system.

Rings: 2
Scaffold atoms: 12
Chemicals: 178
With full pages: 43

Scaffold SMILES

O=c1[nH]ncn1-c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold Open the 4-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one page

Murcko scaffold O=c1[nH]ncn1-c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 178 chemicals

1,2,4-Triazolidine-3,5-dione, 4-phenyl-, ion(1-) chemical structure, C8H6N3O2-, CAS 135257-89-5

1,2,4-Triazolidine-3,5-dione, 4-phenyl-, ion(1-)

CAS 135257-89-5C₈H₆N₃O₂-

1,2,4-Triazolidine-3,5-dione, 1-methyl-4-phenyl-, ion(1-) chemical structure, C9H8N3O2-, CAS 135283-77-1

1,2,4-Triazolidine-3,5-dione, 1-methyl-4-phenyl-, ion(1-)

CAS 135283-77-1C₉H₈N₃O₂-

4-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one chemical structure, C8H7N3O, CAS 1008-30-6

4-Phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one

CAS 1008-30-6C₈H₇N₃O

5-Methyl-4-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C10H11N3O, CAS 79369-38-3

5-Methyl-4-(4-methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 79369-38-3C₁₀H₁₁N₃O

4-(4-Methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C9H9N3O, CAS 93192-57-5

4-(4-Methylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 93192-57-5C₉H₉N₃O

4-(2,6-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C11H13N3O, CAS 6071-12-1

4-(2,6-Dimethylphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 6071-12-1C₁₁H₁₃N₃O

3-Methylsulfanyl-4-phenyl-1H-1,2,4-triazol-5-one chemical structure, C9H9N3OS, CAS 7746-66-9

3-Methylsulfanyl-4-phenyl-1H-1,2,4-triazol-5-one

CAS 7746-66-9C₉H₉N₃OS

Ethyl 2-[3-methyl-4-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate chemical structure, C14H17N3O3, CAS 860785-39-3

Ethyl 2-[3-methyl-4-(4-methylphenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

CAS 860785-39-3C₁₄H₁₇N₃O₃

Ethyl 2-(3-methyl-5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate chemical structure, C13H15N3O3, CAS 860785-45-1

Ethyl 2-(3-methyl-5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate

CAS 860785-45-1C₁₃H₁₅N₃O₃

2-(3-Methyl-5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetonitrile chemical structure, C11H10N4O, CAS 860785-46-2

2-(3-Methyl-5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetonitrile

CAS 860785-46-2C₁₁H₁₀N₄O

4-(4-Bromophenyl)-1H-1,2,4-triazol-5(4H)-one chemical structure, C8H6BrN3O, CAS 214117-50-7

4-(4-Bromophenyl)-1H-1,2,4-triazol-5(4H)-one

CAS 214117-50-7C₈H₆BrN₃O

4-(4-Isopropylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C11H13N3O, CAS 155431-47-3

4-(4-Isopropylphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 155431-47-3C₁₁H₁₃N₃O

4-[3-(Trifluoromethyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C9H6F3N3O, CAS 80240-41-1

4-[3-(Trifluoromethyl)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 80240-41-1C₉H₆F₃N₃O

2-{5-Oxo-4-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetonitrile chemical structure, C11H7F3N4O, CAS 343373-32-0

2-{5-Oxo-4-[3-(trifluoromethyl)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetonitrile

CAS 343373-32-0C₁₁H₇F₃N₄O

Ethyl 2-(5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate chemical structure, C12H13N3O3, CAS 199335-40-5

Ethyl 2-(5-oxo-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-1-yl)acetate

CAS 199335-40-5C₁₂H₁₃N₃O₃

Ethyl 2-[4-(4-bromophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate chemical structure, C12H12BrN3O3, CAS 343373-40-0

Ethyl 2-[4-(4-bromophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetate

CAS 343373-40-0C₁₂H₁₂BrN₃O₃

4-[4-(Trifluoromethoxy)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C9H6F3N3O2, CAS 155431-35-9

4-[4-(Trifluoromethoxy)phenyl]-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 155431-35-9C₉H₆F₃N₃O₂

4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one chemical structure, C9H8FN3O, CAS 860650-60-8

4-(3-Fluorophenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one

CAS 860650-60-8C₉H₈FN₃O

4-(4-Chlorophenyl)-3-methyl-1H-1,2,4-triazol-5-one chemical structure, C9H8ClN3O, CAS 92672-86-1

4-(4-Chlorophenyl)-3-methyl-1H-1,2,4-triazol-5-one

CAS 92672-86-1C₉H₈ClN₃O

4-(4-Fluorophenyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one chemical structure, C9H8FN3O, CAS 860650-96-0

4-(4-Fluorophenyl)-3-methyl-1H-1,2,4-triazol-5(4H)-one

CAS 860650-96-0C₉H₈FN₃O

2-[4-(4-Fluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetonitrile chemical structure, C11H9FN4O, CAS 860651-05-4

2-[4-(4-Fluorophenyl)-3-methyl-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetonitrile

CAS 860651-05-4C₁₁H₉FN₄O

Ethyl 4-(4-fluorophenyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazole-1-acetate chemical structure, C13H14FN3O3, CAS 860651-06-5

Ethyl 4-(4-fluorophenyl)-4,5-dihydro-3-methyl-5-oxo-1H-1,2,4-triazole-1-acetate

CAS 860651-06-5C₁₃H₁₄FN₃O₃

2-[4-(4-Bromophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetic acid chemical structure, C10H8BrN3O3, CAS 339018-24-5

2-[4-(4-Bromophenyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl]acetic acid

CAS 339018-24-5C₁₀H₈BrN₃O₃

2-{5-Oxo-4-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetic acid chemical structure, C11H8F3N3O4, CAS 860612-21-1

2-{5-Oxo-4-[4-(trifluoromethoxy)phenyl]-4,5-dihydro-1H-1,2,4-triazol-1-yl}acetic acid

CAS 860612-21-1C₁₁H₈F₃N₃O₄