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Murcko scaffold

Ring system with 4 rings and 25 atoms

14 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
25
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(CSc1nnc(-c2ccccc2)[nH]1)Nc1nc2ccccc2s1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nnc(-c2ccccc2)[nH]1)Nc1nc2ccccc2s1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(2-fluorophenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H16FN5OS2, CAS 767326-45-4
N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(2-fluorophenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 767326-45-4C19H16FN5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H19N5OS2, CAS 713097-06-4
N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(2-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 713097-06-4C20H19N5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H16BrN5OS2, CAS 713095-85-3
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-bromophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 713095-85-3C19H16BrN5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[4-methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H17N5OS2, CAS 694457-96-0
N-(1,3-Benzothiazol-2-yl)-2-[[4-methyl-5-(3-methylphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 694457-96-0C19H17N5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[5-(2,4-dichlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C19H15Cl2N5OS2, CAS 694463-43-9
N-(1,3-Benzothiazol-2-yl)-2-[[5-(2,4-dichlorophenyl)-4-ethyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 694463-43-9C19H15Cl2N5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]thio]acetamide chemical structure, C19H17N5O2S2, CAS 694465-12-8
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-methoxyphenyl)-4-methyl-1,2,4-triazol-3-yl]thio]acetamide
CAS 694465-12-8C19H17N5O2S2
2-[[4-Amino-5-(4-chlorophenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-benzothiazol-2-yl)acetamide chemical structure, C17H13ClN6OS2, CAS 713096-12-9
2-[[4-Amino-5-(4-chlorophenyl)-1,2,4-triazol-3-yl]sulfanyl]-N-(1,3-benzothiazol-2-yl)acetamide
CAS 713096-12-9C17H13ClN6OS2
N-(1,3-Benzothiazol-2-yl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide chemical structure, C18H15N5OS2, CAS 694477-27-5
N-(1,3-Benzothiazol-2-yl)-2-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]acetamide
CAS 694477-27-5C18H15N5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C20H19N5O2S2, CAS 694478-49-4
N-(1,3-Benzothiazol-2-yl)-2-[[4-ethyl-5-(4-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 694478-49-4C20H19N5O2S2
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C21H19N5OS2, CAS 701952-12-7
N-(1,3-Benzothiazol-2-yl)-2-[[5-(4-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 701952-12-7C21H19N5OS2
N-(1,3-Benzothiazol-2-yl)-2-[[5-(2-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide chemical structure, C21H19N5OS2, CAS 708280-39-1
N-(1,3-Benzothiazol-2-yl)-2-[[5-(2-methylphenyl)-4-prop-2-enyl-1,2,4-triazol-3-yl]sulfanyl]acetamide
CAS 708280-39-1C21H19N5OS2
2-[[4-Amino-5-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl]thio]-N-(6-ethoxy-2-benzothiazolyl)acetamide chemical structure, C19H17FN6O2S2, CAS 879361-77-0
2-[[4-Amino-5-(2-fluorophenyl)-4H-1,2,4-triazol-3-yl]thio]-N-(6-ethoxy-2-benzothiazolyl)acetamide
CAS 879361-77-0C19H17FN6O2S2
N-(1,3-Benzothiazol-2-yl)-2-{[4-ethyl-5-(2-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C20H19N5O2S2, CAS 891307-19-0
N-(1,3-Benzothiazol-2-yl)-2-{[4-ethyl-5-(2-methoxyphenyl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 891307-19-0C20H19N5O2S2
N-(1,3-Benzothiazol-2-yl)-2-{[5-(2-ethoxyphenyl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide chemical structure, C22H21N5O2S2, CAS 891308-12-6
N-(1,3-Benzothiazol-2-yl)-2-{[5-(2-ethoxyphenyl)-4-(prop-2-en-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetamide
CAS 891308-12-6C22H21N5O2S2