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Murcko scaffold

2-(4-Phenylthiazol-2-yl)isoindoline-1,3-dione scaffold

6 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
22
Chemicals
6
With full pages
2
Scaffold SMILES

O=C1c2ccccc2C(=O)N1c1nc(-c2ccccc2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(4-Phenylthiazol-2-yl)isoindoline-1,3-dione page
Murcko scaffold O=C1c2ccccc2C(=O)N1c1nc(-c2ccccc2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 6 of 6 chemicals

4-Nitro-2-(4-phenylthiazol-2-yl)isoindoline-1,3-dione chemical structure, C17H9N3O4S, CAS 324049-77-6
4-Nitro-2-(4-phenylthiazol-2-yl)isoindoline-1,3-dione
CAS 324049-77-6C17H9N3O4S
2-(4-Phenylthiazol-2-yl)isoindoline-1,3-dione chemical structure, C17H10N2O2S, CAS 15850-24-5
2-(4-Phenylthiazol-2-yl)isoindoline-1,3-dione
CAS 15850-24-5C17H10N2O2S
2-[5-Methyl-4-(4-methylphenyl)-1,3-thiazol-2-yl]isoindole-1,3-dione chemical structure, C19H14N2O2S, CAS 774558-43-9
2-[5-Methyl-4-(4-methylphenyl)-1,3-thiazol-2-yl]isoindole-1,3-dione
CAS 774558-43-9C19H14N2O2S
Thiazole-5-acetic acid, 4-(p-chlorophenyl)-2-(1,3-dioxo-2-isoindolyl)-, methyl ester chemical structure, C20H13ClN2O4S, CAS 71013-48-4
Thiazole-5-acetic acid, 4-(p-chlorophenyl)-2-(1,3-dioxo-2-isoindolyl)-, methyl ester
CAS 71013-48-4C20H13ClN2O4S
Thiazole-5-acetic acid, 4-(p-chlorophenyl)-2-(1,3-dioxo-2-isoindolyl)- chemical structure, C19H11ClN2O4S, CAS 71013-50-8
Thiazole-5-acetic acid, 4-(p-chlorophenyl)-2-(1,3-dioxo-2-isoindolyl)-
CAS 71013-50-8C19H11ClN2O4S
2-[4-(4-Bromophenyl)-2-thiazolyl]-1H-isoindole-1,3(2H)-dione chemical structure, C17H9BrN2O2S, CAS 312590-32-2
2-[4-(4-Bromophenyl)-2-thiazolyl]-1H-isoindole-1,3(2H)-dione
CAS 312590-32-2C17H9BrN2O2S