CompoundList
Sign in
Murcko scaffold

3-Phenyl-1-(piperazin-1-yl)propan-1-one scaffold

65 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
16
Chemicals
65
With full pages
7
Scaffold SMILES

O=C(CCc1ccccc1)N1CCNCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 3-Phenyl-1-(piperazin-1-yl)propan-1-one page
Murcko scaffold O=C(CCc1ccccc1)N1CCNCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 65 chemicals

1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-isopropyl- chemical structure, C20H31N3O5, CAS 53335-22-1
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-isopropyl-
CAS 53335-22-1C20H31N3O5
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-methyl-, oxalate chemical structure, C20H29N3O9, CAS 58493-17-7
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-methyl-, oxalate
CAS 58493-17-7C20H29N3O9
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-propyl-, oxalate chemical structure, C22H33N3O9, CAS 58493-18-8
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N-propyl-, oxalate
CAS 58493-18-8C22H33N3O9
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N,N-dimethyl-, oxalate chemical structure, C21H31N3O9, CAS 58493-19-9
1-Piperazineacetamide, 4-((3,5-dimethoxy-4-hydroxy)dihydrocinnamoyl)-N,N-dimethyl-, oxalate
CAS 58493-19-9C21H31N3O9
1-[4-(2-Hydroxyethyl)piperazin-1-yl]-3-phenylpropan-1-one chemical structure, C15H22N2O2, CAS 909087-96-3
1-[4-(2-Hydroxyethyl)piperazin-1-yl]-3-phenylpropan-1-one
CAS 909087-96-3C15H22N2O2
1-(4-Methylpiperazin-1-yl)-3-phenylpropan-1-one chemical structure, C14H20N2O, CAS 346692-97-5
1-(4-Methylpiperazin-1-yl)-3-phenylpropan-1-one
CAS 346692-97-5C14H20N2O
2,2,2-Trifluoro-N-[1-(4-methoxyphenyl)-3-(4-methylpiperazin-1-yl)-3-oxopropyl]acetamide chemical structure, C17H22F3N3O3, CAS 439108-86-8
2,2,2-Trifluoro-N-[1-(4-methoxyphenyl)-3-(4-methylpiperazin-1-yl)-3-oxopropyl]acetamide
CAS 439108-86-8C17H22F3N3O3
2-Amino-1-(4-methylpiperazin-1-yl)-3-phenylpropan-1-one chemical structure, C14H21N3O, CAS 1097625-13-2
2-Amino-1-(4-methylpiperazin-1-yl)-3-phenylpropan-1-one
CAS 1097625-13-2C14H21N3O
2-Amino-1-(4-ethylpiperazin-1-yl)-3-phenylpropan-1-one chemical structure, C15H23N3O, CAS 1008946-30-2
2-Amino-1-(4-ethylpiperazin-1-yl)-3-phenylpropan-1-one
CAS 1008946-30-2C15H23N3O
3-Phenyl-1-(4-prop-2-enylpiperazin-1-yl)propan-1-one chemical structure, C16H22N2O, CAS 915900-70-8
3-Phenyl-1-(4-prop-2-enylpiperazin-1-yl)propan-1-one
CAS 915900-70-8C16H22N2O
3-(4-Methoxyphenyl)-1-(4-prop-2-enylpiperazin-1-yl)propan-1-one chemical structure, C17H24N2O2, CAS 485797-29-3
3-(4-Methoxyphenyl)-1-(4-prop-2-enylpiperazin-1-yl)propan-1-one
CAS 485797-29-3C17H24N2O2
3-Phenyl-1-(piperazin-1-yl)propan-1-one chemical structure, C13H18N2O, CAS 117132-90-8
3-Phenyl-1-(piperazin-1-yl)propan-1-one
CAS 117132-90-8C13H18N2O
3-Phenyl-1-(piperazin-1-yl)butan-1-one chemical structure, C14H20N2O, CAS 926206-96-4
3-Phenyl-1-(piperazin-1-yl)butan-1-one
CAS 926206-96-4C14H20N2O
3-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-propanone chemical structure, C14H20N2O2, CAS 287199-25-1
3-(2-Hydroxyphenyl)-1-(4-methylpiperazino)-1-propanone
CAS 287199-25-1C14H20N2O2
1-[4-(Methylsulfonyl)piperazin-1-yl]-3-[4-(propan-2-yl)phenyl]propan-1-one chemical structure, C17H26N2O3S, CAS 938019-53-5
1-[4-(Methylsulfonyl)piperazin-1-yl]-3-[4-(propan-2-yl)phenyl]propan-1-one
CAS 938019-53-5C17H26N2O3S
3-(4-Methoxyphenyl)-1-(piperazin-1-yl)propan-1-one chemical structure, C14H20N2O2, CAS 1016750-87-0
3-(4-Methoxyphenyl)-1-(piperazin-1-yl)propan-1-one
CAS 1016750-87-0C14H20N2O2
3-(3-Aminophenyl)-1-(4-methylpiperazinyl)propan-1-one chemical structure, C14H21N3O, CAS 454482-13-4
3-(3-Aminophenyl)-1-(4-methylpiperazinyl)propan-1-one
CAS 454482-13-4C14H21N3O
3-(3-Nitrophenyl)-1-(4-methylpiperazinyl)propan-1-one chemical structure, C14H19N3O3, CAS 618446-02-9
3-(3-Nitrophenyl)-1-(4-methylpiperazinyl)propan-1-one
CAS 618446-02-9C14H19N3O3
3-(4-Aminophenyl)-1-(4-methylpiperazin-1-yl)propan-1-one chemical structure, C14H21N3O, CAS 1018545-28-2
3-(4-Aminophenyl)-1-(4-methylpiperazin-1-yl)propan-1-one
CAS 1018545-28-2C14H21N3O
2-Amino-1-(4-methylpiperazin-1-yl)-3-phenylpropan-1-one dihydrochloride chemical structure, C14H23Cl2N3O, CAS 2126159-60-0
2-Amino-1-(4-methylpiperazin-1-yl)-3-phenylpropan-1-one dihydrochloride
CAS 2126159-60-0C14H23Cl2N3O
3-(3-Methylphenyl)-1-(piperazin-1-yl)propan-1-one chemical structure, C14H20N2O, CAS 1082532-48-6
3-(3-Methylphenyl)-1-(piperazin-1-yl)propan-1-one
CAS 1082532-48-6C14H20N2O
3-(4-Ethylphenyl)-1-(piperazin-1-yl)propan-1-one chemical structure, C15H22N2O, CAS 1082532-49-7
3-(4-Ethylphenyl)-1-(piperazin-1-yl)propan-1-one
CAS 1082532-49-7C15H22N2O
3-(4-Aminophenyl)-1-(4-ethylpiperazin-1-yl)propan-1-one chemical structure, C15H23N3O, CAS 1018508-23-0
3-(4-Aminophenyl)-1-(4-ethylpiperazin-1-yl)propan-1-one
CAS 1018508-23-0C15H23N3O
3-(3-Aminophenyl)-1-(4-ethylpiperazin-1-yl)propan-1-one chemical structure, C15H23N3O, CAS 1018530-61-4
3-(3-Aminophenyl)-1-(4-ethylpiperazin-1-yl)propan-1-one
CAS 1018530-61-4C15H23N3O