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Murcko scaffold

2-Phenylquinazoline scaffold

355 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
355
With full pages
25
Scaffold SMILES

c1ccc(-c2ncc3ccccc3n2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenylquinazoline page
Murcko scaffold c1ccc(-c2ncc3ccccc3n2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 355 chemicals

4-Chloro-2-phenylquinazoline chemical structure, C14H9ClN2, CAS 6484-25-9
4-Chloro-2-phenylquinazoline
CAS 6484-25-9C14H9ClN2
2-{2-[(1e)-3,3-Diethyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine chemical structure, C18H20N6, CAS 52698-03-0
2-{2-[(1e)-3,3-Diethyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine
CAS 52698-03-0C18H20N6
2-{2-[(1e)-3,3-Dipropyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine chemical structure, C20H24N6, CAS 52698-04-1
2-{2-[(1e)-3,3-Dipropyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine
CAS 52698-04-1C20H24N6
6-Bromo-2-(3-bromophenyl)quinazolin-4-amine chemical structure, C14H9Br2N3, CAS 62888-06-6
6-Bromo-2-(3-bromophenyl)quinazolin-4-amine
CAS 62888-06-6C14H9Br2N3
2-(2-Amino-5-bromophenyl)-6-bromoquinazolin-4-amine chemical structure, C14H10Br2N4, CAS 62888-15-7
2-(2-Amino-5-bromophenyl)-6-bromoquinazolin-4-amine
CAS 62888-15-7C14H10Br2N4
2-{2-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine chemical structure, C16H16N6, CAS 62888-13-5
2-{2-[(1E)-3,3-Dimethyltriaz-1-en-1-yl]phenyl}quinazolin-4-amine
CAS 62888-13-5C16H16N6
4,7-Dichloro-2-phenylquinazoline chemical structure, C14H8Cl2N2, CAS 54665-92-8
4,7-Dichloro-2-phenylquinazoline
CAS 54665-92-8C14H8Cl2N2
4,6-Dichloro-2-phenylquinazoline chemical structure, C14H8Cl2N2, CAS 54665-93-9
4,6-Dichloro-2-phenylquinazoline
CAS 54665-93-9C14H8Cl2N2
Quinazoline, 4-(2-methoxyethoxy)-2-phenyl- chemical structure, C17H16N2O2, CAS 188569-23-5
Quinazoline, 4-(2-methoxyethoxy)-2-phenyl-
CAS 188569-23-5C17H16N2O2
2-(2-Iodophenyl)quinazolin-4-amine chemical structure, C14H10IN3, CAS 62786-13-4
2-(2-Iodophenyl)quinazolin-4-amine
CAS 62786-13-4C14H10IN3
N(1),N(1)-Dimethyl-N(2)-(2-phenyl-4-quinazolinyl)-1,2-ethanediamine chemical structure, C18H20N4, CAS 106823-85-2
N(1),N(1)-Dimethyl-N(2)-(2-phenyl-4-quinazolinyl)-1,2-ethanediamine
CAS 106823-85-2C18H20N4
alpha-Di-n-butylaminomethyl-2-(4-chlorophenyl)-5-quinazolinemethanol chemical structure, C24H30ClN3O, CAS 52171-80-9
alpha-Di-n-butylaminomethyl-2-(4-chlorophenyl)-5-quinazolinemethanol
CAS 52171-80-9C24H30ClN3O
4-Methoxy-2-phenylquinazoline chemical structure, C15H12N2O, CAS 26060-03-7
4-Methoxy-2-phenylquinazoline
CAS 26060-03-7C15H12N2O
4-(Dichloromethyl)-6-methyl-2-(4-methylphenyl)quinazoline chemical structure, C17H14Cl2N2, CAS 59455-83-3
4-(Dichloromethyl)-6-methyl-2-(4-methylphenyl)quinazoline
CAS 59455-83-3C17H14Cl2N2
2-[4-(tert-Butylamino)-2-quinazolinyl]phenol chemical structure, C18H19N3O, CAS 433966-69-9
2-[4-(tert-Butylamino)-2-quinazolinyl]phenol
CAS 433966-69-9C18H19N3O
2-(2-Chlorophenyl)-N-propan-2-ylquinazolin-4-amine chemical structure, C17H16ClN3, CAS 354992-38-4
2-(2-Chlorophenyl)-N-propan-2-ylquinazolin-4-amine
CAS 354992-38-4C17H16ClN3
2-(2-Chlorophenyl)-N,N-diethylquinazolin-4-amine chemical structure, C18H18ClN3, CAS 371956-90-0
2-(2-Chlorophenyl)-N,N-diethylquinazolin-4-amine
CAS 371956-90-0C18H18ClN3
2-(4-Chlorophenyl)-4-methoxyquinazoline chemical structure, C15H11ClN2O, CAS 83800-99-1
2-(4-Chlorophenyl)-4-methoxyquinazoline
CAS 83800-99-1C15H11ClN2O
2-(4-Chlorophenyl)-4-ethoxyquinazoline chemical structure, C16H13ClN2O, CAS 59524-98-0
2-(4-Chlorophenyl)-4-ethoxyquinazoline
CAS 59524-98-0C16H13ClN2O
2-(2-Chlorophenyl)-4-propan-2-yloxyquinazoline chemical structure, C17H15ClN2O, CAS 371217-77-5
2-(2-Chlorophenyl)-4-propan-2-yloxyquinazoline
CAS 371217-77-5C17H15ClN2O
N-Isopropyl-2-phenyl-4-quinazolinamine chemical structure, C17H17N3, CAS 71028-42-7
N-Isopropyl-2-phenyl-4-quinazolinamine
CAS 71028-42-7C17H17N3
4-Chloro-2-(4-nitrophenyl)quinazoline chemical structure, C14H8ClN3O2, CAS 83800-97-9
4-Chloro-2-(4-nitrophenyl)quinazoline
CAS 83800-97-9C14H8ClN3O2
4-Chloro-2-(4-methylphenyl)quinazoline chemical structure, C15H11ClN2, CAS 59490-96-9
4-Chloro-2-(4-methylphenyl)quinazoline
CAS 59490-96-9C15H11ClN2
2-(4-tert-Butylphenyl)-4-chloroquinazoline chemical structure, C18H17ClN2, CAS 59455-94-6
2-(4-tert-Butylphenyl)-4-chloroquinazoline
CAS 59455-94-6C18H17ClN2