Murcko scaffold
Cyclopropylbenzene scaffold
19,216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 19,216
- With full pages
- 778
Scaffold SMILES
c1ccc(C2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1,681 to 1,728 of 19,216 chemicals
(2-(4-Methoxyphenyl)cyclopropyl)-N-methylmethanamine
CAS 1266871-30-0C12H17NO
(2-(3,5-Dichlorophenyl)cyclopropyl)methanamine
CAS 1269534-38-4C10H11Cl2N
![[2-(2,3-Dichlorophenyl)cyclopropyl]methanamine chemical structure, C10H11Cl2N, CAS 1267449-93-3](/s/HGQVAQJYSRDGDC-UHFFFAOYSA-N.svg)
[2-(2,3-Dichlorophenyl)cyclopropyl]methanamine
CAS 1267449-93-3C10H11Cl2N
![[2-(3-Chlorophenyl)cyclopropyl]methanamine chemical structure, C10H12ClN, CAS 1225706-91-1](/s/KCIZHIBGICXAIM-UHFFFAOYSA-N.svg)
[2-(3-Chlorophenyl)cyclopropyl]methanamine
CAS 1225706-91-1C10H12ClN
![[2-(3-Fluorophenyl)cyclopropyl]methylamine chemical structure, C10H12FN, CAS 1267075-25-1](/s/ASHHTAGUESNAIP-UHFFFAOYSA-N.svg)
[2-(3-Fluorophenyl)cyclopropyl]methylamine
CAS 1267075-25-1C10H12FN
(2-(P-Tolyl)cyclopropyl)methanamine
CAS 1225498-94-1C11H15N
![[2-(2-Methylphenyl)cyclopropyl]methanamine chemical structure, C11H15N, CAS 1225478-58-9](/s/NIZRNCXPTRPDNO-UHFFFAOYSA-N.svg)
[2-(2-Methylphenyl)cyclopropyl]methanamine
CAS 1225478-58-9C11H15N
(2-(3-Methylphenyl)cyclopropyl)methylamine
CAS 1226323-76-7C11H15N
Cyclopropanemethanamine, 2-(2,4-difluorophenyl)-
CAS 1267351-42-7C10H11F2N
(2-(3,4-Dimethylphenyl)cyclopropyl)methanamine
CAS 1269531-02-3C12H17N
(2-(3-Methoxyphenyl)cyclopropyl)methanamine
CAS 1225499-45-5C11H15NO
![4-[2-(Aminomethyl)cyclopropyl]-N,N-diethylaniline chemical structure, C14H22N2, CAS 1267874-90-7](/s/IZPPELIVXYQZQR-UHFFFAOYSA-N.svg)
4-[2-(Aminomethyl)cyclopropyl]-N,N-diethylaniline
CAS 1267874-90-7C14H22N2
(2-(3,4-Dichlorophenyl)cyclopropyl)methanamine
CAS 1267240-40-3C10H11Cl2N
![[2-(2,4-Dichlorophenyl)cyclopropyl]methanamine chemical structure, C10H11Cl2N, CAS 1267595-94-7](/s/QQFQGKPYXWBPBJ-UHFFFAOYSA-N.svg)
[2-(2,4-Dichlorophenyl)cyclopropyl]methanamine
CAS 1267595-94-7C10H11Cl2N
![[2-(4-Chlorophenyl)cyclopropyl]methanamine chemical structure, C10H12ClN, CAS 1226195-39-6](/s/DIYMKPLIASICGD-UHFFFAOYSA-N.svg)
[2-(4-Chlorophenyl)cyclopropyl]methanamine
CAS 1226195-39-6C10H12ClN
![1-[2-(2,3-Dichlorophenyl)cyclopropyl]ethan-1-ol chemical structure, C11H12Cl2O, CAS 1269530-16-6](/s/MOEPTMHNKIILEJ-UHFFFAOYSA-N.svg)
1-[2-(2,3-Dichlorophenyl)cyclopropyl]ethan-1-ol
CAS 1269530-16-6C11H12Cl2O
![1-[2-(3,4-Dimethylphenyl)cyclopropyl]ethan-1-ol chemical structure, C13H18O, CAS 1269532-16-2](/s/QHYNQMYSKHTPDE-UHFFFAOYSA-N.svg)
1-[2-(3,4-Dimethylphenyl)cyclopropyl]ethan-1-ol
CAS 1269532-16-2C13H18O
![Cyclopropanemethanamine, 2-[4-(difluoromethoxy)phenyl]- chemical structure, C11H13F2NO, CAS 1278662-51-3](/s/YLAYUIMEMDLUBM-UHFFFAOYSA-N.svg)
Cyclopropanemethanamine, 2-[4-(difluoromethoxy)phenyl]-
CAS 1278662-51-3C11H13F2NO
![[2-(4-Fluorophenyl)cyclopropyl]methanol chemical structure, C10H11FO, CAS 1278662-25-1](/s/ODPZTCKFPWLUEV-UHFFFAOYSA-N.svg)
[2-(4-Fluorophenyl)cyclopropyl]methanol
CAS 1278662-25-1C10H11FO
![{2-[4-(Trifluoromethyl)phenyl]cyclopropyl}methylamine chemical structure, C11H12F3N, CAS 1267449-56-8](/s/YOWILGGJTLQJCW-UHFFFAOYSA-N.svg)
{2-[4-(Trifluoromethyl)phenyl]cyclopropyl}methylamine
CAS 1267449-56-8C11H12F3N
![[2-(3-Trifluoromethyl-phenyl)-cyclopropyl]-methanol chemical structure, C11H11F3O, CAS 1188541-93-6](/s/CUHAGPDZUGMJIR-UHFFFAOYSA-N.svg)
[2-(3-Trifluoromethyl-phenyl)-cyclopropyl]-methanol
CAS 1188541-93-6C11H11F3O
![{2-[3-(Trifluoromethyl)phenyl]cyclopropyl}methylamine chemical structure, C11H12F3N, CAS 1278662-29-5](/s/HMVDYILQOBDJFR-UHFFFAOYSA-N.svg)
{2-[3-(Trifluoromethyl)phenyl]cyclopropyl}methylamine
CAS 1278662-29-5C11H12F3N
2-(4-Hydroxy-3,5-dimethoxyphenyl)cyclopropane-1-carboxylic acid
CAS 1269527-53-8C12H14O5
2-(4-(Diethylamino)phenyl)cyclopropane-1-carboxylic acid
CAS 1267874-87-2C14H19NO2
- 4-(2-Aminocyclopropyl)-N,N-diethylaniline1267392-08-4C13H20N2
- 1-Amino-2-(2-methoxyphenyl)cyclopropanecarboxylic acid1269534-93-1C11H13NO3
- 1-Amino-2-(2-chloro-6-fluorophenyl)cyclopropanecarboxylic acid1269534-80-6C10H9ClFNO2
- 1-Phenylcyclopropane-1-carboximidamide1029476-06-9C10H12N2
- 2-Phenylcyclopropane-1-sulfonyl chloride927636-13-3C9H9ClO2S
- 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methyl-N-(propan-2-yl)propanamide1324089-08-8C16H21Cl2NO2
- 2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methyl-N-(2-methylpropyl)propanamide1324097-73-5C17H23Cl2NO2
- Ethyl 2-(4-hydroxyphenyl)cyclopropane-1-carboxylate865867-85-2C12H14O3
- (3-Cyclopropylphenyl)methanamine852877-59-9C10H13N
- 1-(2,4,5-Trifluorophenyl)cyclopropane-1-carbonitrile1260649-95-3C10H6F3N
- 1-(2,4,6-Trifluorophenyl)cyclopropane-1-carbonitrile1260763-21-0C10H6F3N
- 1-(2,5-Dimethoxyphenyl)cyclopropane-1-carbonitrile1260850-98-3C12H13NO2
- 1-(2-Chloro-4-fluorophenyl)cyclopropanecarbonitrile1260650-46-1C10H7ClFN
- 1-(3,4,5-Trifluorophenyl)cyclopropane-1-carbonitrile1260794-33-9C10H6F3N
- 1-(3,5-Difluorophenyl)cyclopropanecarbonitrile1205642-06-3C10H7F2N
- 1-(4-Chlorophenyl)cyclopropane-1-carboximidamide763909-14-4C10H11ClN2
- 1-(4-Fluoro-3-(trifluoromethyl)phenyl)cyclopropanecarbonitrile1260874-03-0C11H7F4N
- (2-(Trifluoromethyl)cyclopropyl)benzene1822956-84-2C10H9F3
- 1-(2-Bromo-4-chlorophenyl)cyclopropylamine1204580-93-7C9H9BrClN
- 1-(Bromomethyl)-2-cyclopropylbenzene1260801-90-8C10H11Br
- 1-(Bromomethyl)-3-cyclopropylbenzene1260850-05-2C10H11Br
- 1-Cyclopropyl-2-fluorobenzene1260887-59-9C9H9F
- 1-Cyclopropyl-3-iodobenzene1260852-26-3C9H9I
- 1-(4-(Trifluoromethyl)phenyl)cyclopropanamine474709-86-9C10H10F3N
Related scaffolds
Same ring framework with different atoms or bond orders
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C1CC(C2CC2)CCO111 chemicals![Scaffold O=c1ccnc(C2CC2)[nH]1](/scaffold/HADXIKCWXJVQEO-UHFFFAOYSA-N/structure.svg)
O=c1ccnc(C2CC2)[nH]111 chemicals