Murcko scaffold
Cyclopropylbenzene scaffold
19,216 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 9
- Chemicals
- 19,216
- With full pages
- 778
Scaffold SMILES
c1ccc(C2CC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 193 to 240 of 19,216 chemicals
4-Bromo-1-cyclopropyl-2-nitrobenzene
CAS 5133-36-8C9H8BrNO2
1-(2,4-Dichlorophenyl)cyclopropanecarboxylic acid
CAS 84604-70-6C10H8Cl2O2
(1S,2R)-2-Phenylcyclopropanecarboxylic acid
CAS 23020-18-0C10H10O2
1-(4-Cyclopropyl-3-nitrophenyl)ethanone
CAS 39773-69-8C11H11NO3
Tranylcypromine hydrazide, cis-
CAS 17364-52-2C10H12N2O
rel-(1R,2R)-2-Phenylcyclopropanecarboxylic acid hydrazide
C10H12N2O
trans-2-Phenylcyclopropanecarboxylic hydrazide
CAS 14561-40-1C10H12N2O
2-Phenyl-1-cyclopropanecarboxylic acid, (1R-cis)-
CAS 48126-51-8C10H10O2
2-Phenyl-1-cyclopropanecarboxylic acid, (1S-trans)-
CAS 23020-15-7C10H10O2
Ethyl (1S,2S)-2-phenylcyclopropane-1-carboxylate
CAS 34702-96-0C12H14O2
Ethyl (1R,2S)-2-phenylcyclopropane-1-carboxylate
CAS 946-38-3C12H14O2
rac-Ethyl (1R,2R)-2-(4-methoxyphenyl)cyclopropane-1-carboxylate
CAS 207279-34-3C13H16O3
trans-Ethyl 2-(4-methoxyphenyl)cyclopropanecarboxylate
CAS 6142-64-9C13H16O3
RefChem:313934
CAS 67478-53-9C13H16O3
![Cyclopropanecarboxylic acid, 2-[4-(1,1-dimethylethyl)phenyl]-, trans- chemical structure, C14H18O2, CAS 105393-30-4](/s/ANPQFLQUUUWDQU-NWDGAFQWSA-N.svg)
Cyclopropanecarboxylic acid, 2-[4-(1,1-dimethylethyl)phenyl]-, trans-
CAS 105393-30-4C14H18O2
(1R,2R)-2-(4-Methylphenyl)cyclopropane-1-carbohydrazide
CAS 2173998-97-3C11H14N2O
2-Cyclopropylbenzoic acid
CAS 3158-74-5C10H10O2
3-Cyclopropyl-4-nitrobenzoic acid
CAS 368433-86-7C10H9NO4
1-Cyclopropyl-4,5-dimethoxy-2-nitrobenzene
CAS 714210-44-3C11H13NO4
1-(2,4-Dichlorophenyl)cyclopropanecarbonitrile
CAS 71463-55-3C10H7Cl2N
![Rac-1-[(1r,2r)-2-(4-chlorophenyl)cyclopropyl]ethan-1-one chemical structure, C11H11ClO, CAS 30625-63-9](/s/UBHKMDYUOAVGAN-QWRGUYRKSA-N.svg)
Rac-1-[(1r,2r)-2-(4-chlorophenyl)cyclopropyl]ethan-1-one
CAS 30625-63-9C11H11ClO
rac-1-((1R,2R)-2-(4-Methoxyphenyl)cyclopropyl)ethan-1-one
CAS 30625-68-4C12H14O2
![1-[(1R,2R)-2-(4-Fluorophenyl)cyclopropyl]ethanone chemical structure, C11H11FO, CAS 1218071-65-8](/s/SESKHXRAACJREI-QWRGUYRKSA-N.svg)
1-[(1R,2R)-2-(4-Fluorophenyl)cyclopropyl]ethanone
CAS 1218071-65-8C11H11FO
1-(1-Methylcyclopropyl)-4-nitrobenzene
CAS 40088-88-8C10H11NO2
- ((1R,2R)-2-Phenylcyclopropyl)methanol936-98-1C10H12O
- 1-(4-Cyclopropylphenyl)propan-1-one30170-62-8C12H14O
- 11 suppliersTranylcypromine hydrochloride1986-47-6C9H12ClN
- 1-(4-Chlorophenyl)-1-cyclopropanemethanol80866-81-5C10H11ClO
- 1-[4-(2,2-Dichlorocyclopropyl)phenyl]ethan-1-one40641-93-8C11H10Cl2O
- 1 suppliers(1R,2R)-N-Boc-1-amino-2-phenylcyclopropanecarboxylic acid180322-86-5C15H19NO4
- 1 suppliersrac-(1R,2S)-1-(((tert-Butoxy)carbonyl)amino)-2-phenylcyclopropane-1-carboxylic acid99200-89-2C15H19NO4
- 1-Phenyl-cyclopropanecarbonyl chloride63201-02-5C10H9ClO
- Diethyl 2-(4-chlorophenyl)cyclopropane-1,1-dicarboxylate74444-83-0C15H17ClO4
- 1-[2-(4-Chlorophenyl)cyclopropyl]-1-ethanone54064-34-5C11H11ClO
- 1-[2-(4-Propan-2-ylphenyl)cyclopropyl]ethanone303986-67-6C14H18O
- (2S)-Ethyl 2-phenylcyclopropanecarboxylate1315055-85-6C12H14O2
- 1-(2,2-Dibromo-1-methylcyclopropyl)-4-methoxybenzene52178-73-1C11H12Br2O
- 1-(2,2-Dichlorocyclopropyl)-4-methoxybenzene38365-53-6C10H10Cl2O
- Benzene, 1-chloro-4-(2,2-dichlorocyclopropyl)-33489-96-2C9H7Cl3
- Methyl 2,2-dichloro-alpha-(dichloromethylene)-1-phenylcyclopropanepropanoate83249-03-0C14H12Cl4O2
- 1-(4-Fluorophenyl)cyclopropanecarbonitrile97009-67-1C10H8FN
- Ethanethiol, 2-((2-phenylcyclopropyl)methylamino)-, hydrogen sulfate (ester) (E)-78128-72-0C12H17NO3S2
- Cyclopropanecarboxamide, 2-((acetylamino)methyl)-N,N-diethyl-1-phenyl-, cis-105310-24-5C17H24N2O2
- 2-(Aminomethyl)-1-phenylcyclopropane-1-carboxylic acid--hydrogen chloride (1/1)105310-28-9C11H14ClNO2
- Cyclopropanecarboxylic acid, 2-(aminomethyl)-1-phenyl-, cis-69160-57-2C11H13NO2
- Cyclopropanecarboxylic acid, 2-((dimethylamino)methyl)-1-phenyl-, ethyl ester, hydrochloride, trans-105310-33-6C15H22ClNO2
- Cyclopropanecarboxamide, 2-(aminomethyl)-1-phenyl-, monohydrochloride, cis-105310-34-7C11H15ClN2O
- Cyclopropanecarboxamide, 2-(aminomethyl)-N,N-dihexyl-1-phenyl-, cis-, ethanedioate (1:1)105310-96-1C25H40N2O5
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(C2CO2)cc1108 chemicals
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c1ccc(C2N=N2)cc135 chemicals
c1cc(C2CC2)ncn126 chemicals
c1cc(C2CC2)ccn124 chemicals
C1CNCC(C2CC2)C115 chemicals
C1CC(C2CC2)CCN115 chemicals
C1CCC(C2CC2)CC115 chemicals
C1CC(C2CC2)CCO111 chemicals![Scaffold O=c1ccnc(C2CC2)[nH]1](/scaffold/HADXIKCWXJVQEO-UHFFFAOYSA-N/structure.svg)
O=c1ccnc(C2CC2)[nH]111 chemicals