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Murcko scaffold

6-Phenyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione scaffold

28 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
28
With full pages
5
Scaffold SMILES

O=C1c2cccnc2C(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 6-Phenyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione page
Murcko scaffold O=C1c2cccnc2C(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 28 of 28 chemicals

6-(4-Ethylphenyl)-5H-pyrrolo(3,4-b)pyridine-5,7-dione chemical structure, C15H12N2O2, CAS 126104-21-0
6-(4-Ethylphenyl)-5H-pyrrolo(3,4-b)pyridine-5,7-dione
CAS 126104-21-0C15H12N2O2
N-(2,6-Dimethylphenyl)-2,3-pyridinedicarboximide chemical structure, C15H12N2O2, CAS 115062-74-3
N-(2,6-Dimethylphenyl)-2,3-pyridinedicarboximide
CAS 115062-74-3C15H12N2O2
3-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)benzoic acid chemical structure, C14H8N2O4, CAS 294892-44-7
3-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)benzoic acid
CAS 294892-44-7C14H8N2O4
6-(3-Iodophenyl)pyrrolo[3,4-b]pyridine-5,7-dione chemical structure, C13H7IN2O2, CAS 364597-08-0
6-(3-Iodophenyl)pyrrolo[3,4-b]pyridine-5,7-dione
CAS 364597-08-0C13H7IN2O2
6-(4-Methoxyphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C14H10N2O3, CAS 37458-43-8
6-(4-Methoxyphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 37458-43-8C14H10N2O3
4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)benzoic acid chemical structure, C14H8N2O4, CAS 37458-42-7
4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)benzoic acid
CAS 37458-42-7C14H8N2O4
4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)phenyl acetate chemical structure, C15H10N2O4, CAS 383371-31-1
4-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)phenyl acetate
CAS 383371-31-1C15H10N2O4
6-(2-Methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C14H10N2O2, CAS 152751-78-5
6-(2-Methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 152751-78-5C14H10N2O2
6-(4-Fluorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H7FN2O2, CAS 37458-50-7
6-(4-Fluorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 37458-50-7C13H7FN2O2
5-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-2-methoxyphenyl acetate chemical structure, C16H12N2O5, CAS 354120-87-9
5-(5,7-Dioxo-5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-2-methoxyphenyl acetate
CAS 354120-87-9C16H12N2O5
6-(3-Acetylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C15H10N2O3, CAS 354120-96-0
6-(3-Acetylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 354120-96-0C15H10N2O3
6-Phenyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H8N2O2, CAS 6538-81-4
6-Phenyl-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 6538-81-4C13H8N2O2
6-(3-Methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C14H10N2O2, CAS 152751-77-4
6-(3-Methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 152751-77-4C14H10N2O2
6-(4-Chlorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H7ClN2O2, CAS 37458-38-1
6-(4-Chlorophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 37458-38-1C13H7ClN2O2
[3-(5,7-Dioxopyrrolo[3,4-b]pyridin-6-yl)phenyl] acetate chemical structure, C15H10N2O4, CAS 381709-11-1
[3-(5,7-Dioxopyrrolo[3,4-b]pyridin-6-yl)phenyl] acetate
CAS 381709-11-1C15H10N2O4
6-(4-Isopropylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C16H14N2O2, CAS 354120-85-7
6-(4-Isopropylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 354120-85-7C16H14N2O2
6-(2-Methoxy-5-nitrophenyl)pyrrolo[3,4-b]pyridine-5,7-dione chemical structure, C14H9N3O5, CAS 354120-86-8
6-(2-Methoxy-5-nitrophenyl)pyrrolo[3,4-b]pyridine-5,7-dione
CAS 354120-86-8C14H9N3O5
6-(4-Bromo-2-methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C14H9BrN2O2, CAS 354120-88-0
6-(4-Bromo-2-methylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 354120-88-0C14H9BrN2O2
6-(4-Iodophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H7IN2O2, CAS 384793-65-1
6-(4-Iodophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 384793-65-1C13H7IN2O2
6-(2-Iodophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H7IN2O2, CAS 692261-06-6
6-(2-Iodophenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 692261-06-6C13H7IN2O2
6-(2-Chloro-4-nitrophenyl)pyrrolo[3,4-b]pyridine-5,7-dione chemical structure, C13H6ClN3O4, CAS 633284-67-0
6-(2-Chloro-4-nitrophenyl)pyrrolo[3,4-b]pyridine-5,7-dione
CAS 633284-67-0C13H6ClN3O4
6-(4-Acetylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C15H10N2O3, CAS 139157-06-5
6-(4-Acetylphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 139157-06-5C15H10N2O3
5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 3-methyl-6-phenyl- chemical structure, C14H10N2O2, CAS 102267-93-6
5H-Pyrrolo[3,4-b]pyridine-5,7(6H)-dione, 3-methyl-6-phenyl-
CAS 102267-93-6C14H10N2O2
6-(4-Hydroxyphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione chemical structure, C13H8N2O3, CAS 115062-73-2
6-(4-Hydroxyphenyl)-5H-pyrrolo[3,4-b]pyridine-5,7(6H)-dione
CAS 115062-73-2C13H8N2O3