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Murcko scaffold

Ring system with 3 rings and 21 atoms

19 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
19
With full pages
9
Scaffold SMILES

O=C(CSc1nncc2ccccc12)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CSc1nncc2ccccc12)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 19 of 19 chemicals

N-(2,4-Dichlorophenyl)-2-[(4-methyl-1-phthalazinyl)sulfanyl]acetamide chemical structure, C17H13Cl2N3OS, CAS 337925-50-5
N-(2,4-Dichlorophenyl)-2-[(4-methyl-1-phthalazinyl)sulfanyl]acetamide
CAS 337925-50-5C17H13Cl2N3OS
N-(3-Hydroxyphenyl)-2-phthalazin-1-ylsulfanylacetamide chemical structure, C16H13N3O2S, CAS 710287-50-6
N-(3-Hydroxyphenyl)-2-phthalazin-1-ylsulfanylacetamide
CAS 710287-50-6C16H13N3O2S
Benzoic acid, 4-[2-(phthalazin-1-ylsulfanyl)acetylamino]-, methyl ester chemical structure, C18H15N3O3S, CAS 674364-15-9
Benzoic acid, 4-[2-(phthalazin-1-ylsulfanyl)acetylamino]-, methyl ester
CAS 674364-15-9C18H15N3O3S
N-(2,5-Dimethoxyphenyl)-2-phthalazin-1-ylsulfanylacetamide chemical structure, C18H17N3O3S, CAS 674306-75-3
N-(2,5-Dimethoxyphenyl)-2-phthalazin-1-ylsulfanylacetamide
CAS 674306-75-3C18H17N3O3S
2-(Phthalazin-1-ylsulfanyl)-N-p-tolyl-acetamide chemical structure, C17H15N3OS, CAS 696647-50-4
2-(Phthalazin-1-ylsulfanyl)-N-p-tolyl-acetamide
CAS 696647-50-4C17H15N3OS
N-(2,4-Dimethyl-6-nitrophenyl)-2-phthalazin-1-ylsulfanylacetamide chemical structure, C18H16N4O3S, CAS 697239-43-3
N-(2,4-Dimethyl-6-nitrophenyl)-2-phthalazin-1-ylsulfanylacetamide
CAS 697239-43-3C18H16N4O3S
N-(4-Methoxy-2-nitrophenyl)-2-phthalazin-1-ylsulfanylacetamide chemical structure, C17H14N4O4S, CAS 697239-44-4
N-(4-Methoxy-2-nitrophenyl)-2-phthalazin-1-ylsulfanylacetamide
CAS 697239-44-4C17H14N4O4S
N-(4-Hydroxyphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide chemical structure, C17H15N3O2S, CAS 309726-13-4
N-(4-Hydroxyphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide
CAS 309726-13-4C17H15N3O2S
N-(4-Methylphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide chemical structure, C18H17N3OS, CAS 354539-86-9
N-(4-Methylphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide
CAS 354539-86-9C18H17N3OS
N-(2-Methylphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide chemical structure, C18H17N3OS, CAS 354539-87-0
N-(2-Methylphenyl)-2-(4-methylphthalazin-1-yl)sulfanylacetamide
CAS 354539-87-0C18H17N3OS
Methyl 4-[[2-[(4-methyl-1-phthalazinyl)thio]acetyl]amino]benzoate chemical structure, C19H17N3O3S, CAS 350680-08-9
Methyl 4-[[2-[(4-methyl-1-phthalazinyl)thio]acetyl]amino]benzoate
CAS 350680-08-9C19H17N3O3S
N-(4-Fluorophenyl)-2-phthalazin-1-ylsulfanylacetamide chemical structure, C16H12FN3OS, CAS 727670-73-7
N-(4-Fluorophenyl)-2-phthalazin-1-ylsulfanylacetamide
CAS 727670-73-7C16H12FN3OS
2-[(4-Methylphthalazin-1-yl)sulfanyl]-N-phenylacetamide chemical structure, C17H15N3OS, CAS 330836-37-8
2-[(4-Methylphthalazin-1-yl)sulfanyl]-N-phenylacetamide
CAS 330836-37-8C17H15N3OS
N-(3,4-Dichlorophenyl)-2-[(4-methylphthalazin-1-yl)sulfanyl]acetamide chemical structure, C17H13Cl2N3OS, CAS 372495-81-3
N-(3,4-Dichlorophenyl)-2-[(4-methylphthalazin-1-yl)sulfanyl]acetamide
CAS 372495-81-3C17H13Cl2N3OS
N-(2-Ethoxyphenyl)-2-(phthalazin-1-ylsulfanyl)acetamide chemical structure, C18H17N3O2S, CAS 710287-31-3
N-(2-Ethoxyphenyl)-2-(phthalazin-1-ylsulfanyl)acetamide
CAS 710287-31-3C18H17N3O2S
N-(2,4-Dimethoxyphenyl)-2-(4-methylphthalazinylthio)acetamide chemical structure, C19H19N3O3S, CAS 923107-71-5
N-(2,4-Dimethoxyphenyl)-2-(4-methylphthalazinylthio)acetamide
CAS 923107-71-5C19H19N3O3S
Methyl 4,5-dimethoxy-2-[2-(4-methylphthalazinylthio)acetylamino]benzoate chemical structure, C21H21N3O5S, CAS 923235-14-7
Methyl 4,5-dimethoxy-2-[2-(4-methylphthalazinylthio)acetylamino]benzoate
CAS 923235-14-7C21H21N3O5S
N-(2,5-Dimethylphenyl)-2-(phthalazin-1-ylsulfanyl)acetamide chemical structure, C18H17N3OS, CAS 924861-26-7
N-(2,5-Dimethylphenyl)-2-(phthalazin-1-ylsulfanyl)acetamide
CAS 924861-26-7C18H17N3OS
N-(2-Ethoxyphenyl)-2-[(4-methylphthalazin-1-yl)sulfanyl]acetamide chemical structure, C19H19N3O2S, CAS 1440249-14-8
N-(2-Ethoxyphenyl)-2-[(4-methylphthalazin-1-yl)sulfanyl]acetamide
CAS 1440249-14-8C19H19N3O2S