Murcko scaffold
N-(5-Oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide scaffold
23 chemicals on CompoundList share this ring system.
- Rings
- 4
- Scaffold atoms
- 25
- Chemicals
- 23
- With full pages
- 6
Scaffold SMILES
O=C(Cc1ccccc1)Nc1c2c(nn1-c1ccccc1)CS(=O)C2
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 23 of 23 chemicals
![N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(3,4-dimethoxyphenyl)acetamide chemical structure, C21H20ClN3O4S, CAS 958701-91-2](/s/UXGADKXXKJNJSS-UHFFFAOYSA-N.svg)
N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(3,4-dimethoxyphenyl)acetamide
CAS 958701-91-2C21H20ClN3O4S
![2-(3,4-Dimethoxyphenyl)-N-[2-(4-fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C21H20FN3O4S, CAS 958702-00-6](/s/QAIGOEGJGULXFM-UHFFFAOYSA-N.svg)
2-(3,4-Dimethoxyphenyl)-N-[2-(4-fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 958702-00-6C21H20FN3O4S
![2-(3,4-Dimethoxyphenyl)-N-[2-(4-methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C22H23N3O5S, CAS 1007194-00-4](/s/VMPZBSDSWMHNDM-UHFFFAOYSA-N.svg)
2-(3,4-Dimethoxyphenyl)-N-[2-(4-methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 1007194-00-4C22H23N3O5S
![2-(3,4-Dimethoxyphenyl)-N-(2-(2,3-dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C23H25N3O4S, CAS 958710-82-2](/s/KFSPDGPRJGSWSO-UHFFFAOYSA-N.svg)
2-(3,4-Dimethoxyphenyl)-N-(2-(2,3-dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 958710-82-2C23H25N3O4S
![N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-fluorophenyl)acetamide chemical structure, C19H15ClFN3O2S, CAS 958711-00-7](/s/NMJOTNGXUKGPMC-UHFFFAOYSA-N.svg)
N-[2-(3-Chlorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-fluorophenyl)acetamide
CAS 958711-00-7C19H15ClFN3O2S
![2-(4-Fluorophenyl)-N-[2-(4-methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide chemical structure, C20H18FN3O3S, CAS 1009784-87-5](/s/NPQKRQXXWKJMDN-UHFFFAOYSA-N.svg)
2-(4-Fluorophenyl)-N-[2-(4-methoxyphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide
CAS 1009784-87-5C20H18FN3O3S
![N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(4-fluorophenyl)acetamide chemical structure, C21H20FN3O2S, CAS 958711-03-0](/s/LUYJIZYIPQYEDY-UHFFFAOYSA-N.svg)
N-(2-(2,3-Dimethylphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(4-fluorophenyl)acetamide
CAS 958711-03-0C21H20FN3O2S
![2-(4-Fluorophenyl)-N-(5-oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C20H18FN3O2S, CAS 958711-08-5](/s/KVNZXQJMTRJLDZ-UHFFFAOYSA-N.svg)
2-(4-Fluorophenyl)-N-(5-oxido-2-(o-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 958711-08-5C20H18FN3O2S
![N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide chemical structure, C20H18ClN3O2S, CAS 958703-28-1](/s/KOCKMRPXMNNRLR-UHFFFAOYSA-N.svg)
N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide
CAS 958703-28-1C20H18ClN3O2S
![N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(3-methylphenyl)acetamide chemical structure, C20H18FN3O2S, CAS 1008921-15-0](/s/NVGQLCGGLYRMMM-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(3-methylphenyl)acetamide
CAS 1008921-15-0C20H18FN3O2S
![N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide chemical structure, C21H21N3O3S, CAS 958702-42-6](/s/KALSBYDLQMQEHS-UHFFFAOYSA-N.svg)
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide
CAS 958702-42-6C21H21N3O3S
![N-(5-Oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide chemical structure, C19H17N3O2S, CAS 957624-87-2](/s/VLPAXNBLNFAYER-UHFFFAOYSA-N.svg)
N-(5-Oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide
CAS 957624-87-2C19H17N3O2S
![2-(4-Methoxyphenyl)-N-(5-oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C21H21N3O3S, CAS 1009235-32-8](/s/SUGODOAZCCPQKL-UHFFFAOYSA-N.svg)
2-(4-Methoxyphenyl)-N-(5-oxido-2-(p-tolyl)-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 1009235-32-8C21H21N3O3S
![N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(4-methoxyphenyl)acetamide chemical structure, C20H18ClN3O3S, CAS 958976-82-4](/s/JVTDSBKNECFBRS-UHFFFAOYSA-N.svg)
N-(2-(3-Chlorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(4-methoxyphenyl)acetamide
CAS 958976-82-4C20H18ClN3O3S
![N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-methoxyphenyl)acetamide chemical structure, C20H18FN3O3S, CAS 1008475-29-3](/s/QVQSEJBHNCVPJO-UHFFFAOYSA-N.svg)
N-[2-(4-Fluorophenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-methoxyphenyl)acetamide
CAS 1008475-29-3C20H18FN3O3S
![2-(4-Methoxyphenyl)-N-(2-(4-methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C21H21N3O4S, CAS 1007193-49-8](/s/ZVAYIISWALHSIW-UHFFFAOYSA-N.svg)
2-(4-Methoxyphenyl)-N-(2-(4-methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 1007193-49-8C21H21N3O4S
![N-[2-(2,3-Dimethylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-methoxyphenyl)acetamide chemical structure, C22H23N3O3S, CAS 958976-81-3](/s/NSYNHLYYWBQJMB-UHFFFAOYSA-N.svg)
N-[2-(2,3-Dimethylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-(4-methoxyphenyl)acetamide
CAS 958976-81-3C22H23N3O3S
![N-(2-(4-Fluorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide chemical structure, C19H16FN3O2S, CAS 1008475-27-1](/s/FMOAFZHUBDTMNP-UHFFFAOYSA-N.svg)
N-(2-(4-Fluorophenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide
CAS 1008475-27-1C19H16FN3O2S
![N-(5-Oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide chemical structure, C20H19N3O2S, CAS 1008437-69-1](/s/OSHVJNDIIXUWEZ-UHFFFAOYSA-N.svg)
N-(5-Oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-(m-tolyl)acetamide
CAS 1008437-69-1C20H19N3O2S
![N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-phenylacetamide chemical structure, C20H19N3O2S, CAS 1019099-96-7](/s/QSAVWEMBWBDLRC-UHFFFAOYSA-N.svg)
N-[2-(4-Methylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]-2-phenylacetamide
CAS 1019099-96-7C20H19N3O2S
![2-(4-Fluorophenyl)-N-(5-oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C19H16FN3O2S, CAS 1020478-03-8](/s/RUGIWWURSMESIZ-UHFFFAOYSA-N.svg)
2-(4-Fluorophenyl)-N-(5-oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 1020478-03-8C19H16FN3O2S
![2-(4-Methoxyphenyl)-N-(5-oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide chemical structure, C20H19N3O3S, CAS 1009517-61-6](/s/LAVLGUCCLXMTQT-UHFFFAOYSA-N.svg)
2-(4-Methoxyphenyl)-N-(5-oxido-2-phenyl-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)acetamide
CAS 1009517-61-6C20H19N3O3S
![N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide chemical structure, C20H19N3O3S, CAS 1008919-92-3](/s/SQZSGQCMNKPECQ-UHFFFAOYSA-N.svg)
N-(2-(4-Methoxyphenyl)-5-oxido-4,6-dihydro-2H-thieno[3,4-c]pyrazol-3-yl)-2-phenylacetamide
CAS 1008919-92-3C20H19N3O3S
Related scaffolds
Same ring framework with different atoms or bond orders
