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Murcko scaffold

2-(3-Thienyl)-1,3-dioxolane scaffold

34 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
10
Chemicals
34
With full pages
4
Scaffold SMILES

c1cc(C2OCCO2)cs1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-(3-Thienyl)-1,3-dioxolane page
Murcko scaffold c1cc(C2OCCO2)cs1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 34 of 34 chemicals

2-(3-Thienyl)-1,3-dioxolane chemical structure, C7H8O2S, CAS 13250-82-3
2-(3-Thienyl)-1,3-dioxolane
CAS 13250-82-3C7H8O2S
3-(1,3-Dioxolan-2-yl)thiophene-2-sulfonyl chloride chemical structure, C7H7ClO4S2, CAS 103011-38-7
3-(1,3-Dioxolan-2-yl)thiophene-2-sulfonyl chloride
CAS 103011-38-7C7H7ClO4S2
3-(1,3-Dioxolan-2-yl)thiophene-2-carbaldehyde chemical structure, C8H8O3S, CAS 13250-83-4
3-(1,3-Dioxolan-2-yl)thiophene-2-carbaldehyde
CAS 13250-83-4C8H8O3S
Thiophene, 2,3-dibromo-4-(1,3-dioxolan-2-yl)- chemical structure, C7H6Br2O2S, CAS 61200-57-5
Thiophene, 2,3-dibromo-4-(1,3-dioxolan-2-yl)-
CAS 61200-57-5C7H6Br2O2S
2-Methyl-2-(thiophen-3-yl)-1,3-dioxolane chemical structure, C8H10O2S, CAS 13657-89-1
2-Methyl-2-(thiophen-3-yl)-1,3-dioxolane
CAS 13657-89-1C8H10O2S
3-(1,3-Dioxolan-2-yl)thiophene-2-sulfonamide chemical structure, C7H9NO4S2, CAS 103011-39-8
3-(1,3-Dioxolan-2-yl)thiophene-2-sulfonamide
CAS 103011-39-8C7H9NO4S2
4-(1,3-Dioxolan-2-yl)thiophene-2-sulfonamide chemical structure, C7H9NO4S2, CAS 210827-40-0
4-(1,3-Dioxolan-2-yl)thiophene-2-sulfonamide
CAS 210827-40-0C7H9NO4S2
3-(1,3-Dioxolan-2-yl)-N-(1-methylethyl)-2-thiophenesulfonamide chemical structure, C10H15NO4S2, CAS 286958-38-1
3-(1,3-Dioxolan-2-yl)-N-(1-methylethyl)-2-thiophenesulfonamide
CAS 286958-38-1C10H15NO4S2
2-(5-Bromothiophen-3-yl)-1,3-dioxolane chemical structure, C7H7BrO2S, CAS 79757-69-0
2-(5-Bromothiophen-3-yl)-1,3-dioxolane
CAS 79757-69-0C7H7BrO2S
3-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid chemical structure, C8H8O4S, CAS 934570-44-2
3-(1,3-Dioxolan-2-yl)thiophene-2-carboxylic acid
CAS 934570-44-2C8H8O4S
3-(2-Dioxolanyl)-N-(2-hydroxyethyl)thiophene-2-sulfonamide chemical structure, C9H13NO5S2, CAS 198774-54-8
3-(2-Dioxolanyl)-N-(2-hydroxyethyl)thiophene-2-sulfonamide
CAS 198774-54-8C9H13NO5S2
[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiophen-2-yl]-methanol chemical structure, C9H12O3S, CAS 1161776-28-8
[4-(2-Methyl-[1,3]dioxolan-2-yl)-thiophen-2-yl]-methanol
CAS 1161776-28-8C9H12O3S
2-(5-Chloromethyl-thiophen-3-yl)-2-methyl-[1,3]dioxolane chemical structure, C9H11ClO2S, CAS 1161776-31-3
2-(5-Chloromethyl-thiophen-3-yl)-2-methyl-[1,3]dioxolane
CAS 1161776-31-3C9H11ClO2S
2-{2-[2-(Methanesulfinyl)-2-(methylsulfanyl)ethenyl]thiophen-3-yl}-1,3-dioxolane chemical structure, C11H14O3S3, CAS 61336-55-8
2-{2-[2-(Methanesulfinyl)-2-(methylsulfanyl)ethenyl]thiophen-3-yl}-1,3-dioxolane
CAS 61336-55-8C11H14O3S3
4-[2-(Thiophen-3-yl)-1,3-dioxolan-2-yl]butanenitrile chemical structure, C11H13NO2S, CAS 88098-49-1
4-[2-(Thiophen-3-yl)-1,3-dioxolan-2-yl]butanenitrile
CAS 88098-49-1C11H13NO2S
4-(Chloromethyl)-2-(thiophen-3-yl)-1,3-dioxolane chemical structure, C8H9ClO2S, CAS 1556649-68-3
4-(Chloromethyl)-2-(thiophen-3-yl)-1,3-dioxolane
CAS 1556649-68-3C8H9ClO2S
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-sulfonyl chloride chemical structure, C7H6BrClO4S2, CAS 2059949-40-3
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-sulfonyl chloride
CAS 2059949-40-3C7H6BrClO4S2
[5-Bromo-4-(1,3-dioxolan-2-yl)thiophen-2-yl]methanamine chemical structure, C8H10BrNO2S, CAS 2060060-79-7
[5-Bromo-4-(1,3-dioxolan-2-yl)thiophen-2-yl]methanamine
CAS 2060060-79-7C8H10BrNO2S
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-sulfonamide chemical structure, C7H8BrNO4S2, CAS 2059954-55-9
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-sulfonamide
CAS 2059954-55-9C7H8BrNO4S2
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-carbaldehyde chemical structure, C8H7BrO3S, CAS 2060053-47-4
5-Bromo-4-(1,3-dioxolan-2-yl)thiophene-2-carbaldehyde
CAS 2060053-47-4C8H7BrO3S
4-(1,3-Dioxolan-2-yl)-2,5-dimethylthiophene-3-carbaldehyde chemical structure, C10H12O3S, CAS 2172017-84-2
4-(1,3-Dioxolan-2-yl)-2,5-dimethylthiophene-3-carbaldehyde
CAS 2172017-84-2C10H12O3S
1-[4-(2-Methyl-1,3-dioxolan-2-yl)-3-thienyl]ethanone chemical structure, C10H12O3S, CAS 1072933-67-5
1-[4-(2-Methyl-1,3-dioxolan-2-yl)-3-thienyl]ethanone
CAS 1072933-67-5C10H12O3S
4-(1,3-Dioxolan-2-yl)thiophene-2-sulfonyl chloride chemical structure, C7H7ClO4S2, CAS 2287341-78-8
4-(1,3-Dioxolan-2-yl)thiophene-2-sulfonyl chloride
CAS 2287341-78-8C7H7ClO4S2
4-(1,3-Dioxolan-2-yl)thiophene-3-carbaldehyde chemical structure, C8H8O3S, CAS 78071-38-2
4-(1,3-Dioxolan-2-yl)thiophene-3-carbaldehyde
CAS 78071-38-2C8H8O3S