Murcko scaffold
3-(Benzyloxy)piperidine scaffold
75 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 75
- With full pages
- 2
Scaffold SMILES
c1ccc(COC2CCCNC2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 48 of 75 chemicals
Ethyl 4,4-dimethoxy-3-(phenylmethoxy)piperidine-1-carboxylate
CAS 84176-72-7C17H25NO5
![1-[3-(Benzyloxy)piperidino]-2,2,2-trifluoro-1-ethanone chemical structure, C14H16F3NO2, CAS 866010-38-0](/s/AKJKISFJMWAOMS-UHFFFAOYSA-N.svg)
1-[3-(Benzyloxy)piperidino]-2,2,2-trifluoro-1-ethanone
CAS 866010-38-0C14H16F3NO2
3-Benzyloxy-5-hydroxymethyl-piperidin-4-ol
CAS 220050-90-8C13H19NO3
tert-Butyl (2R,3S)-3-(benzyloxy)-2-(3-bromo-2-oxopropyl)piperidine-1-carboxylate
CAS 290315-11-6C20H28BrNO4
2-Piperidinemethanol, 6-dodecyl-3-(phenylmethoxy)-, (2S,3R,6R)-
CAS 849428-89-3C25H43NO2
3-(Benzyloxy)piperidine
CAS 37098-74-1C12H17NO
![3-[(2-Chlorophenyl)methoxy]piperidine chemical structure, C12H16ClNO, CAS 1121627-63-1](/s/HEUPZTSFCQZAAP-UHFFFAOYSA-N.svg)
3-[(2-Chlorophenyl)methoxy]piperidine
CAS 1121627-63-1C12H16ClNO
![3-{[(3,4-Difluorophenyl)methyl]oxy}piperidine chemical structure, C12H15F2NO, CAS 794464-07-6](/s/SGKRQQQXDMNSMA-UHFFFAOYSA-N.svg)
3-{[(3,4-Difluorophenyl)methyl]oxy}piperidine
CAS 794464-07-6C12H15F2NO
3-(Benzyloxy)piperidine hydrochloride
CAS 1185304-22-6C12H18ClNO
![3-[(2-Methoxybenzyl)oxy]piperidine chemical structure, C13H19NO2, CAS 946759-00-8](/s/SBSYXEBFPMSEJI-UHFFFAOYSA-N.svg)
3-[(2-Methoxybenzyl)oxy]piperidine
CAS 946759-00-8C13H19NO2
![3-[(2-Methylbenzyl)oxy]piperidine chemical structure, C13H19NO, CAS 946714-17-6](/s/NVDNJKGJBMROPH-UHFFFAOYSA-N.svg)
3-[(2-Methylbenzyl)oxy]piperidine
CAS 946714-17-6C13H19NO
![3-[(3-Methylbenzyl)oxy]piperidine chemical structure, C13H19NO, CAS 946680-96-2](/s/JYZWSPHMZXUAPY-UHFFFAOYSA-N.svg)
3-[(3-Methylbenzyl)oxy]piperidine
CAS 946680-96-2C13H19NO
![3-[(4-Fluorobenzyl)oxy]piperidine chemical structure, C12H16FNO, CAS 933736-19-7](/s/HHIHAEIWKSVRHP-UHFFFAOYSA-N.svg)
3-[(4-Fluorobenzyl)oxy]piperidine
CAS 933736-19-7C12H16FNO
![Piperidine, 3-[(2-methoxyphenyl)methoxy]-, hydrochloride (1:1) chemical structure, C13H20ClNO2, CAS 1185299-00-6](/s/BHNXWKXKISGWNK-UHFFFAOYSA-N.svg)
Piperidine, 3-[(2-methoxyphenyl)methoxy]-, hydrochloride (1:1)
CAS 1185299-00-6C13H20ClNO2
![3-[(3-Fluorobenzyl)oxy]piperidine hydrochloride chemical structure, C12H17ClFNO, CAS 1184997-21-4](/s/KGDQHYUELZKVIO-UHFFFAOYSA-N.svg)
3-[(3-Fluorobenzyl)oxy]piperidine hydrochloride
CAS 1184997-21-4C12H17ClFNO
![3-[(3-Chlorobenzyl)oxy]piperidine hydrochloride chemical structure, C12H17Cl2NO, CAS 1185301-25-0](/s/PBFIEAJKIOACMD-UHFFFAOYSA-N.svg)
3-[(3-Chlorobenzyl)oxy]piperidine hydrochloride
CAS 1185301-25-0C12H17Cl2NO
3-((4-Methylbenzyl)oxy)piperidine hydrochloride
CAS 1185301-39-6C13H20ClNO
![3-[[4-(Trifluoromethyl)phenyl]methoxy]-piperidine chemical structure, C13H16F3NO, CAS 1047081-66-2](/s/VTECVRVQVHCGEJ-UHFFFAOYSA-N.svg)
3-[[4-(Trifluoromethyl)phenyl]methoxy]-piperidine
CAS 1047081-66-2C13H16F3NO
3-((2-Chlorobenzyl)oxy)piperidine hydrochloride
CAS 1220017-44-6C12H17Cl2NO
![3-[(2-Fluorobenzyl)oxy]piperidine hydrochloride chemical structure, C12H17ClFNO, CAS 1220033-06-6](/s/RUIGIUGLTKCLPU-UHFFFAOYSA-N.svg)
3-[(2-Fluorobenzyl)oxy]piperidine hydrochloride
CAS 1220033-06-6C12H17ClFNO
![3-[(2-Fluorophenyl)methoxy]piperidine chemical structure, C12H16FNO, CAS 1046921-94-1](/s/ZKHPALXDIDQTKU-UHFFFAOYSA-N.svg)
3-[(2-Fluorophenyl)methoxy]piperidine
CAS 1046921-94-1C12H16FNO
![3-[(3-Bromobenzyl)oxy]piperidine hydrochloride chemical structure, C12H17BrClNO, CAS 1219977-35-1](/s/FOTLXMJVUFFECQ-UHFFFAOYSA-N.svg)
3-[(3-Bromobenzyl)oxy]piperidine hydrochloride
CAS 1219977-35-1C12H17BrClNO
![3-[(3-Bromophenyl)methoxy]piperidine chemical structure, C12H16BrNO, CAS 1121634-26-1](/s/YAAPIEFXFHVHJX-UHFFFAOYSA-N.svg)
3-[(3-Bromophenyl)methoxy]piperidine
CAS 1121634-26-1C12H16BrNO
![3-[(3-Methoxybenzyl)oxy]piperidine hydrochloride chemical structure, C13H20ClNO2, CAS 1220036-58-7](/s/QEBOZVKATFJDRP-UHFFFAOYSA-N.svg)
3-[(3-Methoxybenzyl)oxy]piperidine hydrochloride
CAS 1220036-58-7C13H20ClNO2
- 3-[(4-Bromobenzyl)oxy]piperidine hydrochloride1219976-73-4C12H17BrClNO
- 3-((4-Chlorobenzyl)oxy)piperidine hydrochloride1220033-10-2C12H17Cl2NO
- 3-[(4-Fluorobenzyl)oxy]piperidine hydrochloride1219980-98-9C12H17ClFNO
- 3-[(4-Iodobenzyl)oxy]piperidine hydrochloride1219977-04-4C12H17ClINO
- 3-[(4-Isopropylbenzyl)oxy]piperidine hydrochloride1220033-15-7C15H24ClNO
- 3-((4-Methoxybenzyl)oxy)piperidine hydrochloride1220036-79-2C13H20ClNO2
- 3-[(4-Methoxybenzyl)oxy]piperidine933716-40-6C13H19NO2
- (3R,5S)-5-(Benzyloxy)-1-(tert-butoxycarbonyl)piperidine-3-carboxylic acid1932816-18-6C18H25NO5
- 3-(2,4-Dichloro-benzyloxy)-piperidine hydrochloride1219980-92-3C12H16Cl3NO
- Methyl 2-[(3-piperidinyloxy)methyl]benzoate hydrochloride1220034-16-1C14H20ClNO3
- Methyl 4-[(3-piperidinyloxy)methyl]benzoate hydrochloride1220019-84-0C14H20ClNO3
- 3-[(2,4-Difluorobenzyl)oxy]piperidine hydrochloride1220020-22-3C12H16ClF2NO
- 3-[(2,6-Difluorobenzyl)oxy]piperidine hydrochloride1219977-12-4C12H16ClF2NO
- 3-[(3,5-Difluorobenzyl)oxy]piperidine hydrochloride1220020-26-7C12H16ClF2NO
- 3-[(3,5-Dimethoxybenzyl)oxy]piperidine hydrochloride1220034-38-7C14H22ClNO3
- 3-(2-Chloro-6-fluoro-benzyloxy)-piperidine hydrochloride1289386-44-2C12H16Cl2FNO
- 3-(2,5-Dichloro-benzyloxy)-piperidine hydrochloride1289386-64-6C12H16Cl3NO
- 3-(2,6-Dichloro-benzyloxy)-piperidine hydrochloride1289385-64-3C12H16Cl3NO
- 3-(3,4-Dichloro-benzyloxy)-piperidine hydrochloride1289387-61-6C12H16Cl3NO
- 3-(1-Phenylethoxy)piperidine1458744-02-9C13H19NO
- 3-[(3,4-Dimethoxyphenyl)methoxy]piperidine933758-58-8C14H21NO3
- 3-[(2,4,6-Trimethylphenyl)methoxy]piperidine1282845-43-5C15H23NO
- (3S)-3-[(2-Fluorophenyl)methoxy]piperidine1568182-78-4C12H16FNO
- 3-((2-Methylbenzyl)oxy)piperidine hydrochloride1289388-20-0C13H20ClNO
Related scaffolds
Same ring framework with different atoms or bond orders
O=C(Nc1ccccc1)c1ccccc11,973 chemicals
O=S(=O)(Nc1ccccc1)c1ccccc1978 chemicals
c1ccc(COc2ccccc2)cc1829 chemicals
c1ccc(N=Nc2ccccc2)cc1383 chemicals
C(=Nc1ccccc1)c1ccccc1379 chemicals
O=C(Oc1ccccc1)c1ccccc1309 chemicals
c1ccc(CNc2ccccc2)cc1309 chemicals
C(=Cc1ccccc1)c1ccccc1279 chemicals
c1ccc(CCc2ccccc2)cc1264 chemicals
O=C(Nc1ccccc1)c1cccnc1140 chemicals
O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals