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Murcko scaffold

Ring system with 5 rings and 30 atoms

4 chemicals on CompoundList share this ring system.

Rings
5
Scaffold atoms
30
Chemicals
4
With full pages
1
Scaffold SMILES

c1ccc(CN2C(c3ccccc3)=NC(c3ccccc3)C2c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CN2C(c3ccccc3)=NC(c3ccccc3)C2c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 4 of 4 chemicals

(4S,5S)-1-Benzyl-2,4,5-triphenyl-4,5-dihydro-1H-imidazole chemical structure, C28H24N2, CAS 920515-99-7
(4S,5S)-1-Benzyl-2,4,5-triphenyl-4,5-dihydro-1H-imidazole
CAS 920515-99-7C28H24N2
rac-Ethyl (4R,5R)-5-(4-aminophenyl)-1-benzyl-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate chemical structure, C32H31N3O3, CAS 2271197-82-9
rac-Ethyl (4R,5R)-5-(4-aminophenyl)-1-benzyl-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate
CAS 2271197-82-9C32H31N3O3
1H-Imidazole-4-carboxylic acid, 4,5-dihydro-5-[4-(methylsulfonyl)phenyl]-2,4-diphenyl-1-(phenylmethyl)-, ethyl ester, (4R,5R)-rel- chemical structure, C32H30N2O4S, CAS 1446350-42-0
1H-Imidazole-4-carboxylic acid, 4,5-dihydro-5-[4-(methylsulfonyl)phenyl]-2,4-diphenyl-1-(phenylmethyl)-, ethyl ester, (4R,5R)-rel-
CAS 1446350-42-0C32H30N2O4S
Ethyl (4S,5S)-4-(4-aminophenyl)-3-benzyl-2-(4-methoxyphenyl)-5-phenyl-4H-imidazole-5-carboxylate chemical structure, C32H31N3O3, CAS 1446350-49-7
Ethyl (4S,5S)-4-(4-aminophenyl)-3-benzyl-2-(4-methoxyphenyl)-5-phenyl-4H-imidazole-5-carboxylate
CAS 1446350-49-7C32H31N3O3