Murcko scaffold
Ring system with 3 rings and 15 atoms
106 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 15
- Chemicals
- 106
- With full pages
- 32
Scaffold SMILES
O=C(Nc1nc2ccccc2s1)C1CC1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 49 to 96 of 106 chemicals
![(Z)-N-(6-Acetamido-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C17H21N3O3S, CAS 865174-13-6](/s/FAEDZZJOVGYMRT-UHFFFAOYSA-N.svg)
(Z)-N-(6-Acetamido-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865174-13-6C17H21N3O3S
![N-[3-(2-Methoxyethyl)-6-methylsulfonyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide chemical structure, C15H18N2O4S2, CAS 864977-31-1](/s/UMJOARSVMBJJPP-UHFFFAOYSA-N.svg)
N-[3-(2-Methoxyethyl)-6-methylsulfonyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide
CAS 864977-31-1C15H18N2O4S2
![2-{[(4-Chloro-1,3-benzothiazol-2-yl)amino]carbonyl}cyclopropanecarboxylic acid chemical structure, C12H9ClN2O3S, CAS 866150-62-1](/s/BBLJDYIKFJXKLK-UHFFFAOYSA-N.svg)
2-{[(4-Chloro-1,3-benzothiazol-2-yl)amino]carbonyl}cyclopropanecarboxylic acid
CAS 866150-62-1C12H9ClN2O3S
N-(6-Fluoro-3-methyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide
CAS 477510-79-5C12H11FN2OS
![N-[3-(2-Methoxyethyl)-6-nitro-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide chemical structure, C14H15N3O4S, CAS 864976-76-1](/s/KPOQOEOOYXJZGP-UHFFFAOYSA-N.svg)
N-[3-(2-Methoxyethyl)-6-nitro-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide
CAS 864976-76-1C14H15N3O4S
![(Z)-N-(3-Allyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H13FN2OS, CAS 865248-77-7](/s/KJSPXHSSIALXPI-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-4-fluorobenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865248-77-7C14H13FN2OS
![(Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H15N3O3S2, CAS 865180-15-0](/s/PVNVQFYPVDDTBU-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-6-sulfamoylbenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865180-15-0C14H15N3O3S2
![(Z)-N-(6-Bromo-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H15BrN2O2S, CAS 1006287-66-6](/s/DNFGWLCKBVAZBN-UHFFFAOYSA-N.svg)
(Z)-N-(6-Bromo-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 1006287-66-6C14H15BrN2O2S
N-(4-Methoxy-6-nitro-1,3-benzothiazol-2-yl)cyclopropanecarboxamide
CAS 330189-57-6C12H11N3O4S
![Ethyl 2-[6-bromo-2-(cyclopropanecarbonylimino)-1,3-benzothiazol-3-yl]acetate chemical structure, C15H15BrN2O3S, CAS 865247-12-7](/s/MAZBZUWXFRKHTR-UHFFFAOYSA-N.svg)
Ethyl 2-[6-bromo-2-(cyclopropanecarbonylimino)-1,3-benzothiazol-3-yl]acetate
CAS 865247-12-7C15H15BrN2O3S
![(Z)-Ethyl 2-(2-((cyclopropanecarbonyl)imino)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C15H16N2O3S, CAS 865247-02-5](/s/NZBPFNSMWSJHHO-UHFFFAOYSA-N.svg)
(Z)-Ethyl 2-(2-((cyclopropanecarbonyl)imino)benzo[d]thiazol-3(2H)-yl)acetate
CAS 865247-02-5C15H16N2O3S
N-(6-Chloro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide
CAS 865181-20-0C14H11ClN2OS
N-(3-Prop-2-ynyl-6-sulfamoyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide
CAS 865182-40-7C14H13N3O3S2
![N-[3-(2-Ethoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide chemical structure, C16H20N2O2S, CAS 865162-15-8](/s/NTSLUZILYOHTIY-UHFFFAOYSA-N.svg)
N-[3-(2-Ethoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide
CAS 865162-15-8C16H20N2O2S
![N-[3-(2-Methoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide chemical structure, C15H18N2O2S, CAS 1006269-61-9](/s/VSZQMKAROZIUGE-UHFFFAOYSA-N.svg)
N-[3-(2-Methoxyethyl)-6-methyl-1,3-benzothiazol-2-ylidene]cyclopropanecarboxamide
CAS 1006269-61-9C15H18N2O2S
N-(6-Nitro-1,3-benzothiazol-2-yl)cyclopropanecarboxamide
CAS 401582-89-6C11H9N3O3S
![N-[6-(Dimethylsulfamoyl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide chemical structure, C13H15N3O3S2, CAS 923245-35-6](/s/CCSTWUIGPCZHNS-UHFFFAOYSA-N.svg)
N-[6-(Dimethylsulfamoyl)-1,3-benzothiazol-2-yl]cyclopropanecarboxamide
CAS 923245-35-6C13H15N3O3S2
![(Z)-Ethyl 2-(2-((cyclopropanecarbonyl)imino)-6-(methylsulfonyl)benzo[d]thiazol-3(2H)-yl)acetate chemical structure, C16H18N2O5S2, CAS 865247-41-2](/s/SHNBGKVWLFRUNB-UHFFFAOYSA-N.svg)
(Z)-Ethyl 2-(2-((cyclopropanecarbonyl)imino)-6-(methylsulfonyl)benzo[d]thiazol-3(2H)-yl)acetate
CAS 865247-41-2C16H18N2O5S2
![(Z)-N-(3-(Prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H12N2OS, CAS 865181-07-3](/s/RVWBBCRMRMKHRA-UHFFFAOYSA-N.svg)
(Z)-N-(3-(Prop-2-yn-1-yl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865181-07-3C14H12N2OS
AG-H-09706
CAS 77414-54-1C11H9ClN2OS
![(Z)-N-(3-(2-Ethoxyethyl)-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C16H20N2O4S2, CAS 865173-69-9](/s/QYRCRRZJKIBHQC-UHFFFAOYSA-N.svg)
(Z)-N-(3-(2-Ethoxyethyl)-6-(methylsulfonyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865173-69-9C16H20N2O4S2
![(Z)-N-(6-Fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H15FN2O2S, CAS 1006015-07-1](/s/MWEUYRYOFJSWHM-UHFFFAOYSA-N.svg)
(Z)-N-(6-Fluoro-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 1006015-07-1C14H15FN2O2S
Methyl 2-(cyclopropanecarbonylamino)-1,3-benzothiazole-6-carboxylate
CAS 864860-55-9C13H12N2O3S
![(Z)-N-(3-Allyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide chemical structure, C14H13FN2OS, CAS 865175-35-5](/s/ZXERCEPXFWETCE-UHFFFAOYSA-N.svg)
(Z)-N-(3-Allyl-6-fluorobenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide
CAS 865175-35-5C14H13FN2OS
- N-(4-Fluoro-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide865248-94-8C14H11FN2OS
- N-(3-Methyl-6-methylsulfonyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide683237-33-4C13H14N2O3S2
- N-(4-Methoxy-1,3-benzothiazol-2-yl)cyclopropanecarboxamide77414-55-2C12H12N2O2S
- (Z)-N-(3-Allyl-6-ethoxybenzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide865180-73-0C16H18N2O2S
- N-(4-Methoxy-3-methyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide441291-16-3C13H14N2O2S
- (Z)-N-(6-Ethoxy-3-(2-methoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide865161-92-8C16H20N2O3S
- N-(4,5-Dimethyl-1,3-benzothiazol-2-yl)cyclopropanecarboxamide864860-81-1C13H14N2OS
- (Z)-N-(6-Chloro-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide865162-57-8C15H17ClN2O2S
- (Z)-Ethyl 2-((cyclopropanecarbonyl)imino)-3-(2-ethoxy-2-oxoethyl)-2,3-dihydrobenzo[d]thiazole-6-carboxylate865246-89-5C18H20N2O5S
- N-(6-Bromo-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide865181-38-0C14H11BrN2OS
- Methyl 2-[2-(cyclopropanecarbonylimino)-5,7-dimethyl-1,3-benzothiazol-3-yl]acetate1321658-17-6C16H18N2O3S
- N-(4-Bromo-3-methyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide1321815-12-6C12H11BrN2OS
- Ethyl 2-[2-(cyclopropanecarbonylimino)-5,7-dimethyl-1,3-benzothiazol-3-yl]acetate1321833-87-7C17H20N2O3S
- N-(4,5-Dichloro-1,3-benzothiazol-2-yl)cyclopropanecarboxamide897618-09-6C11H8Cl2N2OS
- N-(5-Chloro-4-methyl-1,3-benzothiazol-2-yl)cyclopropanecarboxamide912768-16-2C12H11ClN2OS
- N-(4,7-Dichloro-1,3-benzothiazol-2-yl)cyclopropanecarboxamide912768-23-1C11H8Cl2N2OS
- N-(4,7-Dimethyl-1,3-benzothiazol-2-yl)cyclopropanecarboxamide912768-30-0C13H14N2OS
- N-(5,7-Dimethyl-1,3-benzothiazol-2-yl)cyclopropanecarboxamide912768-40-2C13H14N2OS
- N-(4-Fluoro-1,3-benzothiazol-2-yl)cyclopropanecarboxamide907974-10-1C11H9FN2OS
- N-(4-Ethyl-1,3-benzothiazol-2-yl)cyclopropanecarboxamide32895-07-1C13H14N2OS
- N-(4-Bromo-1,3-benzothiazol-2-yl)cyclopropanecarboxamide892846-79-6C11H9BrN2OS
- N-(5,6-Dimethoxy-3-methyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide895434-20-5C14H16N2O3S
- N-(3-Ethyl-5,6-dimethoxy-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide895434-60-3C15H18N2O3S
- N-(4-Methoxy-7-methyl-3-propyl-1,3-benzothiazol-2-ylidene)cyclopropanecarboxamide898372-93-5C16H20N2O2S
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