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Murcko scaffold

Ring system with 2 rings and 19 atoms

11 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
19
Chemicals
11
With full pages
3
Scaffold SMILES

O=C(CNCCc1ccccc1)Nc1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(CNCCc1ccccc1)Nc1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 11 of 11 chemicals

Ammonium, dimethylphenethyl((2,6-xylylcarbamoyl)methyl)-, bromide chemical structure, C20H27BrN2O, CAS 3039-08-5
Ammonium, dimethylphenethyl((2,6-xylylcarbamoyl)methyl)-, bromide
CAS 3039-08-5C20H27BrN2O
Ammonium, dimethylphenethyl((phenylcarbamoyl)methyl)-, bromide chemical structure, C18H23BrN2O, CAS 3131-75-7
Ammonium, dimethylphenethyl((phenylcarbamoyl)methyl)-, bromide
CAS 3131-75-7C18H23BrN2O
Acetamide, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-N-(m-trifluoromethylphenyl)- chemical structure, C19H18F6N2O, CAS 47594-08-1
Acetamide, 2-(alpha-methyl-m-trifluoromethylphenethylamino)-N-(m-trifluoromethylphenyl)-
CAS 47594-08-1C19H18F6N2O
N-(2,5-Dimethylphenyl)-2-[(methylsulfonyl)(2-phenylethyl)amino]acetamide chemical structure, C19H24N2O3S, CAS 675862-64-3
N-(2,5-Dimethylphenyl)-2-[(methylsulfonyl)(2-phenylethyl)amino]acetamide
CAS 675862-64-3C19H24N2O3S
N-(4-Bromo-2-fluorophenyl)-2-[(methylsulfonyl)(2-phenylethyl)amino]acetamide chemical structure, C17H18BrFN2O3S, CAS 675862-68-7
N-(4-Bromo-2-fluorophenyl)-2-[(methylsulfonyl)(2-phenylethyl)amino]acetamide
CAS 675862-68-7C17H18BrFN2O3S
N-[4-(Difluoromethoxy)phenyl]-2-[2-(4-methoxyphenyl)ethylamino]acetamide chemical structure, C18H20F2N2O3, CAS 1063646-65-0
N-[4-(Difluoromethoxy)phenyl]-2-[2-(4-methoxyphenyl)ethylamino]acetamide
CAS 1063646-65-0C18H20F2N2O3
2-[[2-(Dimethylamino)-2-phenylethyl]amino]-N-(4-propan-2-ylphenyl)acetamide chemical structure, C21H29N3O, CAS 744204-52-2
2-[[2-(Dimethylamino)-2-phenylethyl]amino]-N-(4-propan-2-ylphenyl)acetamide
CAS 744204-52-2C21H29N3O
4-{[N-(Methylsulfonyl)-N-(2-phenylethyl)glycyl]amino}benzamide chemical structure, C18H21N3O4S, CAS 769160-60-3
4-{[N-(Methylsulfonyl)-N-(2-phenylethyl)glycyl]amino}benzamide
CAS 769160-60-3C18H21N3O4S
N-[(2S)-1-(4-Carboxyanilino)-1-oxopropan-2-yl]-L-phenylalanine chemical structure, C19H20N2O5, CAS 84041-56-5
N-[(2S)-1-(4-Carboxyanilino)-1-oxopropan-2-yl]-L-phenylalanine
CAS 84041-56-5C19H20N2O5
2-(Methylphenethylamino)-propionanilide chemical structure, C18H22N2O, CAS 101785-07-3
2-(Methylphenethylamino)-propionanilide
CAS 101785-07-3C18H22N2O
2-[Methy(2-phenylethyl)amino]-N-[2-(trifluoromethyl)phenyl]acetamide chemical structure, C18H19F3N2O, CAS 926840-57-5
2-[Methy(2-phenylethyl)amino]-N-[2-(trifluoromethyl)phenyl]acetamide
CAS 926840-57-5C18H19F3N2O