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Murcko scaffold

2,3,4,5-Tetrahydro-1H-1,4-benzodiazepin-5-one scaffold

72 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
72
With full pages
6
Scaffold SMILES

O=C1NCCNc2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2,3,4,5-Tetrahydro-1H-1,4-benzodiazepin-5-one page
Murcko scaffold O=C1NCCNc2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 72 chemicals

3-Methoxy-3-methyl-2,4-dihydro-1H-1,4-benzodiazepin-5-one chemical structure, C11H14N2O2, CAS 27545-03-5
3-Methoxy-3-methyl-2,4-dihydro-1H-1,4-benzodiazepin-5-one
CAS 27545-03-5C11H14N2O2
7,9-Dinitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one chemical structure, C9H8N4O5, CAS 115846-71-4
7,9-Dinitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one
CAS 115846-71-4C9H8N4O5
9-Nitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one chemical structure, C9H9N3O3, CAS 328546-65-2
9-Nitro-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one
CAS 328546-65-2C9H9N3O3
9-Amino-1,2,3,4-tetrahydro-1,4-benzodiazepin-5-one chemical structure, C9H11N3O, CAS 328546-66-3
9-Amino-1,2,3,4-tetrahydro-1,4-benzodiazepin-5-one
CAS 328546-66-3C9H11N3O
3-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C10H12N2O, CAS 27545-05-7
3-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 27545-05-7C10H12N2O
7-Bromo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C9H9BrN2O, CAS 455885-78-6
7-Bromo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 455885-78-6C9H9BrN2O
9-Iodo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C9H9IN2O, CAS 328546-79-8
9-Iodo-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 328546-79-8C9H9IN2O
1-Methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one chemical structure, C10H12N2O, CAS 14359-73-0
1-Methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one
CAS 14359-73-0C10H12N2O
7,9-Dichloro-1-methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one chemical structure, C10H10Cl2N2O, CAS 62675-32-5
7,9-Dichloro-1-methyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one
CAS 62675-32-5C10H10Cl2N2O
2,3,4,5-Tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C9H10N2O, CAS 28544-83-4
2,3,4,5-Tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 28544-83-4C9H10N2O
9-Amino-7-fluoro-1,2,3,4-tetrahydro-5H-benzo[e][1,4]diazepin-5-one chemical structure, C9H10FN3O, CAS 328546-75-4
9-Amino-7-fluoro-1,2,3,4-tetrahydro-5H-benzo[e][1,4]diazepin-5-one
CAS 328546-75-4C9H10FN3O
7-Amino-1-methyl-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one chemical structure, C10H13N3O, CAS 1022972-87-7
7-Amino-1-methyl-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one
CAS 1022972-87-7C10H13N3O
8-Amino-1,4-dimethyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C11H15N3O, CAS 1022972-39-9
8-Amino-1,4-dimethyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 1022972-39-9C11H15N3O
8-Amino-1-methyl-3,4-dihydro-2H-1,4-benzodiazepin-5-one chemical structure, C10H13N3O, CAS 1022972-53-7
8-Amino-1-methyl-3,4-dihydro-2H-1,4-benzodiazepin-5-one
CAS 1022972-53-7C10H13N3O
1,2,3,4-Tetrahydro-1-methyl-8-nitro-5H-1,4-benzodiazepin-5-one chemical structure, C10H11N3O3, CAS 1022972-50-4
1,2,3,4-Tetrahydro-1-methyl-8-nitro-5H-1,4-benzodiazepin-5-one
CAS 1022972-50-4C10H11N3O3
8-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one chemical structure, C9H9BrN2O, CAS 1379324-91-0
8-Bromo-3,4-dihydro-1H-benzo[e][1,4]diazepin-5(2H)-one
CAS 1379324-91-0C9H9BrN2O
8-Amino-4-methyl-2,3-dihydro-1H-1,4-benzodiazepin-5-one chemical structure, C10H13N3O, CAS 1022972-31-1
8-Amino-4-methyl-2,3-dihydro-1H-1,4-benzodiazepin-5-one
CAS 1022972-31-1C10H13N3O
9-Amino-1,4-dimethyl-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one chemical structure, C11H15N3O, CAS 1022974-51-1
9-Amino-1,4-dimethyl-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one
CAS 1022974-51-1C11H15N3O
7-Amino-1,2,3,4-tetrahydro-1,4-benzodiazepin-5-one chemical structure, C9H11N3O, CAS 2247690-40-8
7-Amino-1,2,3,4-tetrahydro-1,4-benzodiazepin-5-one
CAS 2247690-40-8C9H11N3O
8-Amino-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one chemical structure, C9H11N3O, CAS 1022972-17-3
8-Amino-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one
CAS 1022972-17-3C9H11N3O
6-Amino-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one chemical structure, C9H11N3O, CAS 1022963-40-1
6-Amino-1,2,3,4-tetrahydro-benzo[e][1,4]diazepin-5-one
CAS 1022963-40-1C9H11N3O
1,4,8-Trimethyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one chemical structure, C12H16N2O, CAS 500734-49-6
1,4,8-Trimethyl-1,2,3,4-tetrahydro-5H-1,4-benzodiazepin-5-one
CAS 500734-49-6C12H16N2O
8-Fluoro-3-methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C10H11FN2O, CAS 1427381-04-1
8-Fluoro-3-methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 1427381-04-1C10H11FN2O
6-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one chemical structure, C10H12N2O, CAS 1427379-64-3
6-Methyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepin-5-one
CAS 1427379-64-3C10H12N2O