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Murcko scaffold

Ring system with 4 rings and 21 atoms

199 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
21
Chemicals
199
With full pages
25
Scaffold SMILES

O=C(OCC1c2ccccc2-c2ccccc21)N1CCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(OCC1c2ccccc2-c2ccccc21)N1CCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 199 chemicals

(S)-N-Fmoc-azetidine-2-carboxylic acid chemical structure, C19H17NO4, CAS 136552-06-2
(S)-N-Fmoc-azetidine-2-carboxylic acid
CAS 136552-06-2C19H17NO4
1-Fmoc-azetidine-3-carboxylic acid chemical structure, C19H17NO4, CAS 193693-64-0
1-Fmoc-azetidine-3-carboxylic acid
CAS 193693-64-0C19H17NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid chemical structure, C19H17NO4, CAS 184763-07-3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid
CAS 184763-07-3C19H17NO4
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidine-2-carboxylic acid chemical structure, C19H17NO4, CAS 374791-02-3
(R)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidine-2-carboxylic acid
CAS 374791-02-3C19H17NO4
(9H-Fluoren-9-yl)methyl 3-hydroxyazetidine-1-carboxylate chemical structure, C18H17NO3, CAS 886510-13-0
(9H-Fluoren-9-yl)methyl 3-hydroxyazetidine-1-carboxylate
CAS 886510-13-0C18H17NO3
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidin-3-yl)acetic acid chemical structure, C20H19NO4, CAS 959236-89-6
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidin-3-yl)acetic acid
CAS 959236-89-6C20H19NO4
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-methylazetidine-1-carboxylate chemical structure, C19H19NO3, CAS 1494538-81-6
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-methylazetidine-1-carboxylate
CAS 1494538-81-6C19H19NO3
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-propylazetidine-1-carboxylate chemical structure, C21H23NO3, CAS 1491515-41-3
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-propylazetidine-1-carboxylate
CAS 1491515-41-3C21H23NO3
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-(propan-2-yl)azetidine-1-carboxylate chemical structure, C21H23NO3, CAS 1463517-61-4
(9H-Fluoren-9-yl)methyl 3-hydroxy-3-(propan-2-yl)azetidine-1-carboxylate
CAS 1463517-61-4C21H23NO3
(9H-Fluoren-9-yl)methyl 3-ethyl-3-hydroxyazetidine-1-carboxylate chemical structure, C20H21NO3, CAS 1495139-98-4
(9H-Fluoren-9-yl)methyl 3-ethyl-3-hydroxyazetidine-1-carboxylate
CAS 1495139-98-4C20H21NO3
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)azetidine-1-carboxylate chemical structure, C19H19NO3, CAS 1493611-41-8
(9H-Fluoren-9-yl)methyl 3-(hydroxymethyl)azetidine-1-carboxylate
CAS 1493611-41-8C19H19NO3
1-(9H-Fluoren-9-ylmethyl) 3-methyl azetidine-1,3-dicarboxylate chemical structure, C20H19NO4, CAS 1820604-93-0
1-(9H-Fluoren-9-ylmethyl) 3-methyl azetidine-1,3-dicarboxylate
CAS 1820604-93-0C20H19NO4
1-(9H-Fluoren-9-ylmethyl) 2-methyl (2S)-azetidine-1,2-dicarboxylate chemical structure, C20H19NO4, CAS 1820575-03-8
1-(9H-Fluoren-9-ylmethyl) 2-methyl (2S)-azetidine-1,2-dicarboxylate
CAS 1820575-03-8C20H19NO4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)azetidine-1-carboxylate chemical structure, C19H19NO3, CAS 1823615-42-4
(9H-Fluoren-9-yl)methyl 2-(hydroxymethyl)azetidine-1-carboxylate
CAS 1823615-42-4C19H19NO3
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidin-2-yl)acetic acid chemical structure, C20H19NO4, CAS 2138138-02-8
2-(1-(((9H-Fluoren-9-yl)methoxy)carbonyl)azetidin-2-yl)acetic acid
CAS 2138138-02-8C20H19NO4
(S)-1-Fmoc-2-methylazetidine-2-carboxylic Acid chemical structure, C20H19NO4, CAS 1384745-40-7
(S)-1-Fmoc-2-methylazetidine-2-carboxylic Acid
CAS 1384745-40-7C20H19NO4
(2R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-2-methyl-azetidine-2-carboxylic acid chemical structure, C20H19NO4, CAS 1384745-43-0
(2R)-1-(9H-Fluoren-9-ylmethoxycarbonyl)-2-methyl-azetidine-2-carboxylic acid
CAS 1384745-43-0C20H19NO4
2-((1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-methylazetidin-3-yl)oxy)acetic acid chemical structure, C21H21NO5, CAS 1592739-14-4
2-((1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-3-methylazetidin-3-yl)oxy)acetic acid
CAS 1592739-14-4C21H21NO5
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)propanoic acid chemical structure, C21H21NO4, CAS 1594944-87-2
2-(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)propanoic acid
CAS 1594944-87-2C21H21NO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-fluoroazetidine-3-carboxylic acid chemical structure, C19H16FNO4, CAS 1934789-60-2
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-fluoroazetidine-3-carboxylic acid
CAS 1934789-60-2C19H16FNO4
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-hydroxyazetidine-3-carboxylic acid chemical structure, C19H17NO5, CAS 2044773-70-6
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-hydroxyazetidine-3-carboxylic acid
CAS 2044773-70-6C19H17NO5
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)oxy]acetic acid chemical structure, C20H19NO5, CAS 2094394-76-8
2-[(1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}azetidin-3-yl)oxy]acetic acid
CAS 2094394-76-8C20H19NO5
(9H-Fluoren-9-yl)methyl 3-formylazetidine-1-carboxylate chemical structure, C19H17NO3, CAS 1823481-56-6
(9H-Fluoren-9-yl)methyl 3-formylazetidine-1-carboxylate
CAS 1823481-56-6C19H17NO3
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methylazetidine-3-carboxylic acid chemical structure, C20H19NO4, CAS 1935170-13-0
1-{[(9H-Fluoren-9-yl)methoxy]carbonyl}-3-methylazetidine-3-carboxylic acid
CAS 1935170-13-0C20H19NO4