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Murcko scaffold

Ring system with 4 rings and 26 atoms

29 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
29
With full pages
1
Scaffold SMILES

O=C(Nc1ccc(-c2cc3ccccc3oc2=O)cc1)c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccc(-c2cc3ccccc3oc2=O)cc1)c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 29 of 29 chemicals

3,5-Dimethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C25H21NO5, CAS 328975-55-9
3,5-Dimethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 328975-55-9C25H21NO5
3,4,5-Trimethoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C25H21NO6, CAS 329197-81-1
3,4,5-Trimethoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 329197-81-1C25H21NO6
N-[3-Chloro-4-(2-oxochromen-3-yl)phenyl]-4-methoxy-3-nitrobenzamide chemical structure, C23H15ClN2O6, CAS 765926-28-1
N-[3-Chloro-4-(2-oxochromen-3-yl)phenyl]-4-methoxy-3-nitrobenzamide
CAS 765926-28-1C23H15ClN2O6
N-[3-Chloro-4-(2-oxochromen-3-yl)phenyl]-4-nitrobenzamide chemical structure, C22H13ClN2O5, CAS 827005-58-3
N-[3-Chloro-4-(2-oxochromen-3-yl)phenyl]-4-nitrobenzamide
CAS 827005-58-3C22H13ClN2O5
3-Fluoro-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C22H14FNO3, CAS 425656-27-5
3-Fluoro-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 425656-27-5C22H14FNO3
2,4-Dimethyl-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C24H19NO3, CAS 672331-28-1
2,4-Dimethyl-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 672331-28-1C24H19NO3
3-Methyl-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H17NO3, CAS 313551-96-1
3-Methyl-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 313551-96-1C23H17NO3
N-[3-Methoxy-4-(2-oxochromen-3-yl)phenyl]-3-nitrobenzamide chemical structure, C23H16N2O6, CAS 378772-30-6
N-[3-Methoxy-4-(2-oxochromen-3-yl)phenyl]-3-nitrobenzamide
CAS 378772-30-6C23H16N2O6
4-Ethoxy-N-[4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide chemical structure, C24H19NO4, CAS 5662-45-3
4-Ethoxy-N-[4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide
CAS 5662-45-3C24H19NO4
2-Fluoro-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H16FNO3, CAS 347323-67-5
2-Fluoro-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 347323-67-5C23H16FNO3
3,4-Dichloro-N-[4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide chemical structure, C22H13Cl2NO3, CAS 352663-61-7
3,4-Dichloro-N-[4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide
CAS 352663-61-7C22H13Cl2NO3
3-Butoxy-N-[3-methoxy-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide chemical structure, C27H25NO5, CAS 425645-49-4
3-Butoxy-N-[3-methoxy-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide
CAS 425645-49-4C27H25NO5
3-Chloro-4-ethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C25H20ClNO4, CAS 313699-49-9
3-Chloro-4-ethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 313699-49-9C25H20ClNO4
3-Methoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H17NO4, CAS 313402-19-6
3-Methoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 313402-19-6C23H17NO4
3-Bromo-4-methoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H16BrNO4, CAS 765926-65-6
3-Bromo-4-methoxy-N-[4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 765926-65-6C23H16BrNO4
4-Cyano-2-fluoro-N-[3-methoxy-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C24H15FN2O4, CAS 838816-43-6
4-Cyano-2-fluoro-N-[3-methoxy-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 838816-43-6C24H15FN2O4
2-Bromo-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H16BrNO3, CAS 347336-72-5
2-Bromo-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 347336-72-5C23H16BrNO3
2-Iodo-N-[3-methyl-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide chemical structure, C23H16INO3, CAS 5762-70-9
2-Iodo-N-[3-methyl-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide
CAS 5762-70-9C23H16INO3
N-[4-(2-Oxochromen-3-yl)phenyl]-3-propoxybenzamide chemical structure, C25H21NO4, CAS 388084-69-3
N-[4-(2-Oxochromen-3-yl)phenyl]-3-propoxybenzamide
CAS 388084-69-3C25H21NO4
3-Bromo-4-methoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C24H18BrNO4, CAS 329196-90-9
3-Bromo-4-methoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 329196-90-9C24H18BrNO4
3-Bromo-N-[3-methyl-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide chemical structure, C23H16BrNO3, CAS 328252-55-7
3-Bromo-N-[3-methyl-4-(2-oxo-2H-chromen-3-yl)phenyl]benzamide
CAS 328252-55-7C23H16BrNO3
2,3,4,5,6-Pentafluoro-N-[3-methoxy-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C23H12F5NO4, CAS 768287-21-4
2,3,4,5,6-Pentafluoro-N-[3-methoxy-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 768287-21-4C23H12F5NO4
3,4,5-Trimethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide chemical structure, C26H23NO6, CAS 832108-23-3
3,4,5-Trimethoxy-N-[3-methyl-4-(2-oxochromen-3-yl)phenyl]benzamide
CAS 832108-23-3C26H23NO6
N-[3-Methyl-4-(2-oxochromen-3-yl)phenyl]-3-nitrobenzamide chemical structure, C23H16N2O5, CAS 329196-91-0
N-[3-Methyl-4-(2-oxochromen-3-yl)phenyl]-3-nitrobenzamide
CAS 329196-91-0C23H16N2O5