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Murcko scaffold

Ring system with 4 rings and 27 atoms

58 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
27
Chemicals
58
With full pages
7
Scaffold SMILES

O=c1c2ccccc2ncn1-c1ccc(NS(=O)(=O)c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1c2ccccc2ncn1-c1ccc(NS(=O)(=O)c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 58 chemicals

3-Methyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C22H19N3O3S, CAS 898455-55-5
3-Methyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898455-55-5C22H19N3O3S
4-Methyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C22H19N3O3S, CAS 898455-58-8
4-Methyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898455-58-8C22H19N3O3S
3,4-Dimethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H21N3O3S, CAS 898455-61-3
3,4-Dimethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898455-61-3C23H21N3O3S
2,4-Dimethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H21N3O3S, CAS 898455-64-6
2,4-Dimethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898455-64-6C23H21N3O3S
3-Fluoro-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C21H16FN3O3S, CAS 898438-69-2
3-Fluoro-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898438-69-2C21H16FN3O3S
4-Fluoro-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C21H16FN3O3S, CAS 898438-71-6
4-Fluoro-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898438-71-6C21H16FN3O3S
N-[2-Methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C22H19N3O3S, CAS 898420-65-0
N-[2-Methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898420-65-0C22H19N3O3S
3-Methyl-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H21N3O3S, CAS 898420-67-2
3-Methyl-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898420-67-2C23H21N3O3S
4-Methyl-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H21N3O3S, CAS 898420-69-4
4-Methyl-N-[2-methyl-4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898420-69-4C23H21N3O3S
4-Ethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide chemical structure, C23H21N3O3S, CAS 898455-97-5
4-Ethyl-N-[4-(2-methyl-4-oxoquinazolin-3-yl)phenyl]benzenesulfonamide
CAS 898455-97-5C23H21N3O3S
2,5-Difluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide chemical structure, C21H15F2N3O3S, CAS 898438-74-9
2,5-Difluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide
CAS 898438-74-9C21H15F2N3O3S
2,5-Difluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C22H17F2N3O3S, CAS 898456-15-0
2,5-Difluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898456-15-0C22H17F2N3O3S
2,4-Difluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide chemical structure, C21H15F2N3O3S, CAS 898438-98-7
2,4-Difluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide
CAS 898438-98-7C21H15F2N3O3S
2,4-Difluoro-N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide chemical structure, C22H17F2N3O3S, CAS 898456-41-2
2,4-Difluoro-N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide
CAS 898456-41-2C22H17F2N3O3S
3,4-Dimethyl-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C24H23N3O3S, CAS 898420-71-8
3,4-Dimethyl-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898420-71-8C24H23N3O3S
2,4-Dimethyl-N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide chemical structure, C24H23N3O3S, CAS 898420-73-0
2,4-Dimethyl-N-[2-methyl-4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide
CAS 898420-73-0C24H23N3O3S
2,4,5-Trimethyl-N-(4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C24H23N3O3S, CAS 898455-67-9
2,4,5-Trimethyl-N-(4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898455-67-9C24H23N3O3S
2,4,6-Trimethyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide chemical structure, C24H23N3O3S, CAS 898428-96-1
2,4,6-Trimethyl-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]benzene-1-sulfonamide
CAS 898428-96-1C24H23N3O3S
3-Fluoro-4-methoxy-N-(4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C22H18FN3O4S, CAS 898455-88-4
3-Fluoro-4-methoxy-N-(4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898455-88-4C22H18FN3O4S
3-Fluoro-4-methoxy-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C23H20FN3O4S, CAS 898420-91-2
3-Fluoro-4-methoxy-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898420-91-2C23H20FN3O4S
3-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C22H18FN3O3S, CAS 898456-09-2
3-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898456-09-2C22H18FN3O3S
4-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide chemical structure, C22H18FN3O3S, CAS 898456-12-7
4-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)benzenesulfonamide
CAS 898456-12-7C22H18FN3O3S
4-Fluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-(trifluoromethyl)benzene-1-sulfonamide chemical structure, C22H15F4N3O3S, CAS 898438-76-1
4-Fluoro-N-[4-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)phenyl]-3-(trifluoromethyl)benzene-1-sulfonamide
CAS 898438-76-1C22H15F4N3O3S
4-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzenesulfonamide chemical structure, C23H17F4N3O3S, CAS 898456-18-3
4-Fluoro-N-(2-methyl-4-(2-methyl-4-oxoquinazolin-3(4H)-yl)phenyl)-3-(trifluoromethyl)benzenesulfonamide
CAS 898456-18-3C23H17F4N3O3S