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Murcko scaffold

2-Phenyl-1,4-dioxane scaffold

45 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
45
With full pages
4
Scaffold SMILES

c1ccc(C2COCCO2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 2-Phenyl-1,4-dioxane page
Murcko scaffold c1ccc(C2COCCO2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 45 of 45 chemicals

Ethyl 3-phenyl-1,4-dioxane-2-carboxylate chemical structure, C13H16O4, CAS 80378-34-3
Ethyl 3-phenyl-1,4-dioxane-2-carboxylate
CAS 80378-34-3C13H16O4
2-Phenyl-1,4-dioxane chemical structure, C10H12O2, CAS 827-53-2
2-Phenyl-1,4-dioxane
CAS 827-53-2C10H12O2
2-(4-Bromophenyl)-1,4-dioxane chemical structure, C10H11BrO2, CAS 1364462-27-0
2-(4-Bromophenyl)-1,4-dioxane
CAS 1364462-27-0C10H11BrO2
5-Phenyl-1,4-dioxane-2-carboxylic acid chemical structure, C11H12O4, CAS 1071506-65-4
5-Phenyl-1,4-dioxane-2-carboxylic acid
CAS 1071506-65-4C11H12O4
4-(1,4-Dioxan-2-yl)aniline chemical structure, C10H13NO2, CAS 1368639-20-6
4-(1,4-Dioxan-2-yl)aniline
CAS 1368639-20-6C10H13NO2
2-(1,4-Dioxan-2-yl)aniline chemical structure, C10H13NO2, CAS 1622835-62-4
2-(1,4-Dioxan-2-yl)aniline
CAS 1622835-62-4C10H13NO2
2-(2-Bromophenyl)-1,4-dioxane chemical structure, C10H11BrO2, CAS 1368634-19-8
2-(2-Bromophenyl)-1,4-dioxane
CAS 1368634-19-8C10H11BrO2
1-(2-Phenyl-1,4-dioxan-2-yl)methanamine chemical structure, C11H15NO2, CAS 2172050-03-0
1-(2-Phenyl-1,4-dioxan-2-yl)methanamine
CAS 2172050-03-0C11H15NO2
(3-Methyl-3-phenyl-1,4-dioxan-2-yl)methanol chemical structure, C12H16O3, CAS 61211-99-2
(3-Methyl-3-phenyl-1,4-dioxan-2-yl)methanol
CAS 61211-99-2C12H16O3
(5-Phenyl-1,4-dioxan-2-yl)methanol chemical structure, C11H14O3, CAS 1370636-85-3
(5-Phenyl-1,4-dioxan-2-yl)methanol
CAS 1370636-85-3C11H14O3
2-(3-Bromophenyl)-1,4-dioxane chemical structure, C10H11BrO2, CAS 1368749-74-9
2-(3-Bromophenyl)-1,4-dioxane
CAS 1368749-74-9C10H11BrO2
3-(1,4-Dioxan-2-yl)aniline chemical structure, C10H13NO2, CAS 1368907-13-4
3-(1,4-Dioxan-2-yl)aniline
CAS 1368907-13-4C10H13NO2
Methyl 3-phenyl-1,4-dioxane-2-carboxylate chemical structure, C12H14O4, CAS 201403-82-9
Methyl 3-phenyl-1,4-dioxane-2-carboxylate
CAS 201403-82-9C12H14O4
rel-(2R,5R)-5-Phenyl-1,4-dioxane-2-carboxylic acid chemical structure, C11H12O4, CAS 1071506-64-3
rel-(2R,5R)-5-Phenyl-1,4-dioxane-2-carboxylic acid
CAS 1071506-64-3C11H12O4
rac-(2R,3R)-3-Phenyl-1,4-dioxane-2-carboxylic acid chemical structure, C11H12O4, CAS 1955514-59-6
rac-(2R,3R)-3-Phenyl-1,4-dioxane-2-carboxylic acid
CAS 1955514-59-6C11H12O4
(2R,3S)-3-Phenyl-1,4-dioxane-2-carboxylic acid chemical structure, C11H12O4, CAS 2301929-65-5
(2R,3S)-3-Phenyl-1,4-dioxane-2-carboxylic acid
CAS 2301929-65-5C11H12O4
4-(1,4-Dioxan-2-yl)benzonitrile chemical structure, C11H11NO2, CAS 1476849-16-7
4-(1,4-Dioxan-2-yl)benzonitrile
CAS 1476849-16-7C11H11NO2
3-Phenyl-1,4-dioxane-2-carboxylic acid chemical structure, C11H12O4, CAS 1706443-88-0
3-Phenyl-1,4-dioxane-2-carboxylic acid
CAS 1706443-88-0C11H12O4
3-(4-Fluorophenyl)-1,4-dioxane-2-carboxylic acid chemical structure, C11H11FO4, CAS 1706452-95-0
3-(4-Fluorophenyl)-1,4-dioxane-2-carboxylic acid
CAS 1706452-95-0C11H11FO4
3-(2-Fluorophenyl)-1,4-dioxane-2-carboxylic acid chemical structure, C11H11FO4, CAS 1706457-10-4
3-(2-Fluorophenyl)-1,4-dioxane-2-carboxylic acid
CAS 1706457-10-4C11H11FO4
3-(3-Fluorophenyl)-1,4-dioxane-2-carboxylic acid chemical structure, C11H11FO4, CAS 1706443-91-5
3-(3-Fluorophenyl)-1,4-dioxane-2-carboxylic acid
CAS 1706443-91-5C11H11FO4
3-(4-Chlorophenyl)-1,4-dioxane-2-carboxylic acid chemical structure, C11H11ClO4, CAS 1706443-94-8
3-(4-Chlorophenyl)-1,4-dioxane-2-carboxylic acid
CAS 1706443-94-8C11H11ClO4
3-(p-Tolyl)-1,4-dioxane-2-carboxylic acid chemical structure, C12H14O4, CAS 1706443-98-2
3-(p-Tolyl)-1,4-dioxane-2-carboxylic acid
CAS 1706443-98-2C12H14O4
3-(4-Methoxyphenyl)-1,4-dioxane-2-carboxylic acid chemical structure, C12H14O5, CAS 1706462-96-5
3-(4-Methoxyphenyl)-1,4-dioxane-2-carboxylic acid
CAS 1706462-96-5C12H14O5