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Murcko scaffold

1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one scaffold

113 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
113
With full pages
2
Scaffold SMILES

O=c1[nH]c2ccccc2n1C1CCN(Cc2ccccc2)CC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,3-Dihydro-1-[1-(phenylmethyl)-4-piperidinyl]-2H-benzimidazol-2-one page
Murcko scaffold O=c1[nH]c2ccccc2n1C1CCN(Cc2ccccc2)CC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 113 of 113 chemicals

1-(1-(4-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H22ClN3O, CAS 521177-51-5
1-(1-(4-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 521177-51-5C20H22ClN3O
1-(1-(3,4-Dihydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H21N3O3, CAS 687978-00-3
1-(1-(3,4-Dihydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 687978-00-3C19H21N3O3
5-Chloro-1-(1-(4-hydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H20ClN3O2, CAS 2575731-79-0
5-Chloro-1-(1-(4-hydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 2575731-79-0C19H20ClN3O2
1-(1-(4-Methoxybenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C21H25N3O2, CAS 521177-94-6
1-(1-(4-Methoxybenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 521177-94-6C21H25N3O2
1-(1-(3-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H22ClN3O, CAS 521177-77-5
1-(1-(3-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 521177-77-5C20H22ClN3O
1-(1-Benzylpiperidin-4-yl)-4,6-dimethyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C21H25N3O, CAS 942220-48-6
1-(1-Benzylpiperidin-4-yl)-4,6-dimethyl-1H-benzo[d]imidazol-2(3H)-one
CAS 942220-48-6C21H25N3O
1-(1-Benzylpiperidin-4-yl)-6-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H23N3O, CAS 849427-13-0
1-(1-Benzylpiperidin-4-yl)-6-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 849427-13-0C20H23N3O
1-(1-Benzylpiperidin-4-yl)-5-nitro-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H20N4O3, CAS 337909-89-4
1-(1-Benzylpiperidin-4-yl)-5-nitro-1H-benzo[d]imidazol-2(3H)-one
CAS 337909-89-4C19H20N4O3
1-(1-Benzylpiperidin-4-yl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H23N3O2, CAS 231962-45-1
1-(1-Benzylpiperidin-4-yl)-5-methoxy-1H-benzo[d]imidazol-2(3H)-one
CAS 231962-45-1C20H23N3O2
5-Chloro-1-(1-(2-methylbenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H22ClN3O, CAS 2575731-82-5
5-Chloro-1-(1-(2-methylbenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 2575731-82-5C20H22ClN3O
1-(1-(2-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H22ClN3O, CAS 521177-73-1
1-(1-(2-Chlorobenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 521177-73-1C20H22ClN3O
5-Chloro-1-(1-(2-hydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C19H20ClN3O2, CAS 2575731-81-4
5-Chloro-1-(1-(2-hydroxybenzyl)piperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
CAS 2575731-81-4C19H20ClN3O2
1-(1-(2-Methoxybenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one chemical structure, C21H25N3O2, CAS 521177-59-3
1-(1-(2-Methoxybenzyl)piperidin-4-yl)-3-methyl-1H-benzo[d]imidazol-2(3H)-one
CAS 521177-59-3C21H25N3O2
1-(1-Benzylpiperidin-4-yl)-3-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C20H23N3O2, CAS 740021-45-8
1-(1-Benzylpiperidin-4-yl)-3-(hydroxymethyl)-1H-benzo[d]imidazol-2(3H)-one
CAS 740021-45-8C20H23N3O2
1-(1-Benzylpiperidin-4-yl)-3-(methoxymethyl)-1H-benzo[d]imidazol-2(3H)-one chemical structure, C21H25N3O2, CAS 802557-72-8
1-(1-Benzylpiperidin-4-yl)-3-(methoxymethyl)-1H-benzo[d]imidazol-2(3H)-one
CAS 802557-72-8C21H25N3O2
Orb3238149 chemical structure, C19H19Cl2N3O, CAS 2575731-77-8
Orb3238149
CAS 2575731-77-8C19H19Cl2N3O
Orb3238150 chemical structure, C24H29ClN4O, CAS 92281-62-4
Orb3238150
CAS 92281-62-4C24H29ClN4O