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Murcko scaffold

Ring system with 3 rings and 18 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
7
With full pages
3
Scaffold SMILES

O=c1[nH]c(=O)n(C2CCCO2)cc1-c1ccco1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1[nH]c(=O)n(C2CCCO2)cc1-c1ccco1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

5-Furan-2-yl-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione chemical structure, C13H14N2O6, CAS 92233-50-6
5-Furan-2-yl-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
CAS 92233-50-6C13H14N2O6
5-(2-Furyl)-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione chemical structure, C13H14N2O6, CAS 127235-62-5
5-(2-Furyl)-1-[(2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione
CAS 127235-62-5C13H14N2O6
5-(5-Bromo-furan-2-yl)-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione chemical structure, C13H13BrN2O6, CAS 134333-69-0
5-(5-Bromo-furan-2-yl)-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
CAS 134333-69-0C13H13BrN2O6
5-(5-Chloro-furan-2-yl)-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione chemical structure, C13H13ClN2O6, CAS 134333-71-4
5-(5-Chloro-furan-2-yl)-1-(4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione
CAS 134333-71-4C13H13ClN2O6
5-(Furan-2-yl)-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione chemical structure, C13H14N2O6
5-(Furan-2-yl)-1-[4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
C13H14N2O6
5-(Furan-2-yl)-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione chemical structure, C13H14N2O6
5-(Furan-2-yl)-1-[(2R,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
C13H14N2O6
5'-(Furan-2-yl)-2'-O-methyluridine chemical structure, C14H16N2O7, CAS 2095417-32-4
5'-(Furan-2-yl)-2'-O-methyluridine
CAS 2095417-32-4C14H16N2O7