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Murcko scaffold

Pyridine, 2,6-bis(4,5-dihydro-2-oxazolyl)- scaffold

60 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
60
With full pages
6
Scaffold SMILES

c1cc(C2=NCCO2)nc(C2=NCCO2)c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Pyridine, 2,6-bis(4,5-dihydro-2-oxazolyl)- page
Murcko scaffold c1cc(C2=NCCO2)nc(C2=NCCO2)c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 60 chemicals

2,6-Bis(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine chemical structure, C15H19N3O2, CAS 131864-69-2
2,6-Bis(4,4-dimethyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine
CAS 131864-69-2C15H19N3O2
2,6-Bis(4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C17H23N3O2, CAS 861642-68-4
2,6-Bis(4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 861642-68-4C17H23N3O2
(S,S)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine chemical structure, C17H23N3O2, CAS 118949-61-4
(S,S)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine
CAS 118949-61-4C17H23N3O2
(R,R)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine chemical structure, C17H23N3O2, CAS 131864-67-0
(R,R)-2,6-Bis(4-isopropyl-2-oxazolin-2-yl)pyridine
CAS 131864-67-0C17H23N3O2
2,6-Bis(4S)(4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine chemical structure, C19H27N3O2, CAS 118949-63-6
2,6-Bis(4S)(4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl)pyridine
CAS 118949-63-6C19H27N3O2
2,6-Bis((R)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C19H27N3O2, CAS 185346-17-2
2,6-Bis((R)-4-(tert-butyl)-4,5-dihydrooxazol-2-yl)pyridine
CAS 185346-17-2C19H27N3O2
4-tert-Butyl-2-[6-(4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl)pyridin-2-yl]-4,5-dihydro-1,3-oxazole chemical structure, C19H27N3O2, CAS 667908-21-6
4-tert-Butyl-2-[6-(4-tert-butyl-4,5-dihydro-1,3-oxazol-2-yl)pyridin-2-yl]-4,5-dihydro-1,3-oxazole
CAS 667908-21-6C19H27N3O2
Pyridine, 2,6-bis(4,5-dihydro-2-oxazolyl)- chemical structure, C11H11N3O2, CAS 165125-95-1
Pyridine, 2,6-bis(4,5-dihydro-2-oxazolyl)-
CAS 165125-95-1C11H11N3O2
((4R,4'R)-Pyridine-2,6-diylbis(4,5-dihydrooxazole-2,4-diyl))dimethanol chemical structure, C13H15N3O4
((4R,4'R)-Pyridine-2,6-diylbis(4,5-dihydrooxazole-2,4-diyl))dimethanol
C13H15N3O4
2,6-Bis((S)-5,5-diethyl-4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C25H39N3O2, CAS 162213-04-9
2,6-Bis((S)-5,5-diethyl-4-isopropyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 162213-04-9C25H39N3O2
2,6-Bis((4S)-4-(sec-butyl)-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C19H27N3O2, CAS 827623-38-1
2,6-Bis((4S)-4-(sec-butyl)-4,5-dihydrooxazol-2-yl)pyridine
CAS 827623-38-1C19H27N3O2
2,6-Bis((R)-4-ethyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C15H19N3O2, CAS 131864-68-1
2,6-Bis((R)-4-ethyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 131864-68-1C15H19N3O2
2-[4-Chloro-6-(4,5-dihydro-1,3-oxazol-2-yl)-2-pyridinyl]-4,5-dihydro-1,3-oxazole chemical structure, C11H10ClN3O2, CAS 600727-92-2
2-[4-Chloro-6-(4,5-dihydro-1,3-oxazol-2-yl)-2-pyridinyl]-4,5-dihydro-1,3-oxazole
CAS 600727-92-2C11H10ClN3O2
2,6-Bis(4,5-dihydro-1,3-oxazol-2-yl)-4-methoxypyridine chemical structure, C12H13N3O3, CAS 600727-94-4
2,6-Bis(4,5-dihydro-1,3-oxazol-2-yl)-4-methoxypyridine
CAS 600727-94-4C12H13N3O3
(4S,4'S)-2,2'-(4-Bromopyridine-2,6-diyl)bis(4-isopropyl-4,5-dihydrooxazole) chemical structure, C17H22BrN3O2, CAS 477351-96-5
(4S,4'S)-2,2'-(4-Bromopyridine-2,6-diyl)bis(4-isopropyl-4,5-dihydrooxazole)
CAS 477351-96-5C17H22BrN3O2
((4R,4'S)-PYridine-2,6-diylbis(4,5-dihydrooxazole-2,4-diyl))dimethanol chemical structure, C13H15N3O4, CAS 1193725-65-3
((4R,4'S)-PYridine-2,6-diylbis(4,5-dihydrooxazole-2,4-diyl))dimethanol
CAS 1193725-65-3C13H15N3O4
2,6-Bis(4-ethyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C15H19N3O2, CAS 182684-46-4
2,6-Bis(4-ethyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 182684-46-4C15H19N3O2
2,6-Bis((S)-4-methyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C13H15N3O2, CAS 189014-95-7
2,6-Bis((S)-4-methyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 189014-95-7C13H15N3O2
(4S,4'S)-2,2'-(4-Chloropyridine-2,6-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) chemical structure, C19H26ClN3O2, CAS 825613-46-5
(4S,4'S)-2,2'-(4-Chloropyridine-2,6-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)
CAS 825613-46-5C19H26ClN3O2
(4S,4'S)-2,2'-(4-Bromopyridine-2,6-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) chemical structure, C19H26BrN3O2, CAS 1130593-57-5
(4S,4'S)-2,2'-(4-Bromopyridine-2,6-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)
CAS 1130593-57-5C19H26BrN3O2
4-((2,6-Bis(4,4-dimethyl-4,5-dihydrooxazol-2-yl)pyridin-4-yl)oxy)butan-1-ol chemical structure, C19H27N3O4, CAS 1254959-95-9
4-((2,6-Bis(4,4-dimethyl-4,5-dihydrooxazol-2-yl)pyridin-4-yl)oxy)butan-1-ol
CAS 1254959-95-9C19H27N3O4
3-((2,6-Bis(4,4-dimethyl-4,5-dihydrooxazol-2-yl)pyridin-4-yl)oxy)propan-1-ol chemical structure, C18H25N3O4, CAS 1303995-55-2
3-((2,6-Bis(4,4-dimethyl-4,5-dihydrooxazol-2-yl)pyridin-4-yl)oxy)propan-1-ol
CAS 1303995-55-2C18H25N3O4
2,6-Bis(4-(sec-butyl)-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C19H27N3O2, CAS 178151-11-6
2,6-Bis(4-(sec-butyl)-4,5-dihydrooxazol-2-yl)pyridine
CAS 178151-11-6C19H27N3O2
2,6-Bis((R)-5-methyl-4,5-dihydrooxazol-2-yl)pyridine chemical structure, C13H15N3O2, CAS 1038922-08-5
2,6-Bis((R)-5-methyl-4,5-dihydrooxazol-2-yl)pyridine
CAS 1038922-08-5C13H15N3O2