Murcko scaffold
N-Benzyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide scaffold
36 chemicals on CompoundList share this ring system.
- Rings
- 3
- Scaffold atoms
- 20
- Chemicals
- 36
- With full pages
- 4
Scaffold SMILES
O=C(NCc1ccccc1)c1cnc2sccn2c1=O
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 36 of 36 chemicals
![5-Oxo-N-(1-phenylethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O2S, CAS 851943-57-2](/s/LHZCTNBXNKETEJ-UHFFFAOYSA-N.svg)
5-Oxo-N-(1-phenylethyl)-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-57-2C15H13N3O2S
![N-(4-Fluorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12FN3O2S, CAS 851944-71-3](/s/QEMIGZSAMUWDOT-UHFFFAOYSA-N.svg)
N-(4-Fluorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-71-3C15H12FN3O2S
![N-Benzyl-N-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O2S, CAS 851943-42-5](/s/UXBJPVFYWXTSQB-UHFFFAOYSA-N.svg)
N-Benzyl-N-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-42-5C15H13N3O2S
![N-(2-Chlorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12ClN3O2S, CAS 851944-70-2](/s/CLBNIMBTCCNZAI-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-70-2C15H12ClN3O2S
![N-(2-Methoxybenzyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O3S, CAS 851943-54-9](/s/DYNSEBNHXXBQNJ-UHFFFAOYSA-N.svg)
N-(2-Methoxybenzyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-54-9C15H13N3O3S
![N-(4-Methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O3S, CAS 851944-72-4](/s/DJSBVFAHYRLMOM-UHFFFAOYSA-N.svg)
N-(4-Methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-72-4C16H15N3O3S
![N-Benzyl-N,3-dimethyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O2S, CAS 851944-67-7](/s/FZWPEOHHENJMMM-UHFFFAOYSA-N.svg)
N-Benzyl-N,3-dimethyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-67-7C16H15N3O2S
![N-[(4-Methylphenyl)methyl]-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O2S, CAS 851943-55-0](/s/OCVNFITZABIEAU-UHFFFAOYSA-N.svg)
N-[(4-Methylphenyl)methyl]-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-55-0C15H13N3O2S
![N-(2-Methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O3S, CAS 851944-73-5](/s/OWJREXUPZWIPMF-UHFFFAOYSA-N.svg)
N-(2-Methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-73-5C16H15N3O3S
![N-(4-Chlorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12ClN3O2S, CAS 851944-77-9](/s/DHAOBEPEDBDIBK-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-77-9C15H12ClN3O2S
![N-(2-Chlorobenzyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C14H10ClN3O2S, CAS 851943-51-6](/s/JZAWGEQEUZZZLE-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-51-6C14H10ClN3O2S
![N-Benzyl-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O2S, CAS 851944-69-9](/s/WJYZEDREPQDBTG-UHFFFAOYSA-N.svg)
N-Benzyl-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-69-9C15H13N3O2S
![N-Benzyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C14H11N3O2S, CAS 851943-50-5](/s/WSMICNGEIUVPHR-UHFFFAOYSA-N.svg)
N-Benzyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851943-50-5C14H11N3O2S
![3-Methyl-5-oxo-N-(1-phenylethyl)-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O2S, CAS 851944-75-7](/s/NMZMGSFXGCZTEL-UHFFFAOYSA-N.svg)
3-Methyl-5-oxo-N-(1-phenylethyl)-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 851944-75-7C16H15N3O2S
![N-Benzyl-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H13N3O2S, CAS 896336-34-8](/s/GVGLFERMURVBEH-UHFFFAOYSA-N.svg)
N-Benzyl-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-34-8C15H13N3O2S
![N-(2-Chlorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12ClN3O2S, CAS 896336-42-8](/s/MTMVHJXMXYYDIY-UHFFFAOYSA-N.svg)
N-(2-Chlorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-42-8C15H12ClN3O2S
![N-(4-Fluorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12FN3O2S, CAS 896336-50-8](/s/VGZZHXQOXRHHRX-UHFFFAOYSA-N.svg)
N-(4-Fluorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-50-8C15H12FN3O2S
![N-(4-Methoxybenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O3S, CAS 896336-57-5](/s/WIQYNRBMZIGJNC-UHFFFAOYSA-N.svg)
N-(4-Methoxybenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-57-5C16H15N3O3S
![N-[(2-Methoxyphenyl)methyl]-2-methyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O3S, CAS 896336-65-5](/s/DBDDQBDGDWWPKI-UHFFFAOYSA-N.svg)
N-[(2-Methoxyphenyl)methyl]-2-methyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-65-5C16H15N3O3S
![2-Methyl-N-(4-methylbenzyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O2S, CAS 896336-73-5](/s/ORGXTMKTJONCJJ-UHFFFAOYSA-N.svg)
2-Methyl-N-(4-methylbenzyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-73-5C16H15N3O2S
![N-(4-Chlorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C15H12ClN3O2S, CAS 896337-04-5](/s/QPJLEUTUJLCHAY-UHFFFAOYSA-N.svg)
N-(4-Chlorobenzyl)-2-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896337-04-5C15H12ClN3O2S
![2-Methyl-5-oxo-N-(1-phenylethyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C16H15N3O2S, CAS 896336-88-2](/s/MHADLBAZQRQWIL-UHFFFAOYSA-N.svg)
2-Methyl-5-oxo-N-(1-phenylethyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 896336-88-2C16H15N3O2S
![N-(3,4-Dimethoxybenzyl)-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C17H17N3O4S, CAS 1031994-82-7](/s/FARUISROWFOGAZ-UHFFFAOYSA-N.svg)
N-(3,4-Dimethoxybenzyl)-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 1031994-82-7C17H17N3O4S
![N-Benzyl-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide chemical structure, C14H11N3O3S, CAS 898457-68-6](/s/JWCYWIPAZUMMPF-UHFFFAOYSA-N.svg)
N-Benzyl-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide
CAS 898457-68-6C14H11N3O3S
- N-(2-Chlorobenzyl)-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898412-28-7C14H10ClN3O3S
- N-(4-Fluorobenzyl)-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898431-58-8C14H10FN3O3S
- 7-Hydroxy-N-(4-methoxybenzyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898457-69-7C15H13N3O4S
- 7-Hydroxy-N-(4-methylbenzyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898412-29-8C15H13N3O3S
- 7-Hydroxy-5-oxo-N-(1-phenylethyl)-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898457-70-0C15H13N3O3S
- N-(4-Chlorobenzyl)-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898412-30-1C14H10ClN3O3S
- 7-Hydroxy-N-(3-methoxybenzyl)-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898457-74-4C15H13N3O4S
- N-(2,6-Difluorobenzyl)-7-hydroxy-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898431-64-6C14H9F2N3O3S
- N-[(4-Fluorophenyl)methyl]-7-hydroxy-3-methyl-5-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxamide898431-71-5C15H12FN3O3S
- 7-Hydroxy-N-(4-methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898457-82-4C16H15N3O4S
- 7-Hydroxy-N-(3-methoxybenzyl)-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide906159-11-3C16H15N3O4S
- N-(2,6-Difluorobenzyl)-7-hydroxy-3-methyl-5-oxo-5H-thiazolo[3,2-a]pyrimidine-6-carboxamide898431-75-9C15H11F2N3O3S
Related scaffolds
Same ring framework with different atoms or bond orders
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