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Murcko scaffold

N-Phenylglutarimide scaffold

32 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
32
With full pages
5
Scaffold SMILES

O=C1CCCC(=O)N1c1ccccc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Phenylglutarimide page
Murcko scaffold O=C1CCCC(=O)N1c1ccccc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 32 of 32 chemicals

1-(3,5-Dichlorophenyl)-2,6-piperidinedione chemical structure, C11H9Cl2NO2, CAS 32809-21-5
1-(3,5-Dichlorophenyl)-2,6-piperidinedione
CAS 32809-21-5C11H9Cl2NO2
N-Phenylglutarimide chemical structure, C11H11NO2, CAS 5768-13-8
N-Phenylglutarimide
CAS 5768-13-8C11H11NO2
1-(4-Hydroxyphenyl)piperidine-2,6-dione chemical structure, C11H11NO3, CAS 423737-09-1
1-(4-Hydroxyphenyl)piperidine-2,6-dione
CAS 423737-09-1C11H11NO3
4-(2,6-Dioxopiperidin-1-yl)benzoic acid chemical structure, C12H11NO4, CAS 147916-40-3
4-(2,6-Dioxopiperidin-1-yl)benzoic acid
CAS 147916-40-3C12H11NO4
4-Methyl-1-(4-methylphenyl)piperidine-2,6-dione chemical structure, C13H15NO2, CAS 883022-85-3
4-Methyl-1-(4-methylphenyl)piperidine-2,6-dione
CAS 883022-85-3C13H15NO2
1-(2,4-Difluorophenyl)-4-methylpiperidine-2,6-dione chemical structure, C12H11F2NO2, CAS 883023-06-1
1-(2,4-Difluorophenyl)-4-methylpiperidine-2,6-dione
CAS 883023-06-1C12H11F2NO2
N-(4-Chlorophenyl)glutarimide chemical structure, C11H10ClNO2, CAS 81305-70-6
N-(4-Chlorophenyl)glutarimide
CAS 81305-70-6C11H10ClNO2
Ethyl 4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate chemical structure, C16H19NO4, CAS 279692-23-8
Ethyl 4-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate
CAS 279692-23-8C16H19NO4
1-(4-Methoxyphenyl)piperidine-2,6-dione chemical structure, C12H13NO3, CAS 138480-41-8
1-(4-Methoxyphenyl)piperidine-2,6-dione
CAS 138480-41-8C12H13NO3
1-(4-Iodophenyl)-2,6-piperidinedione chemical structure, C11H10INO2, CAS 200706-81-6
1-(4-Iodophenyl)-2,6-piperidinedione
CAS 200706-81-6C11H10INO2
1-(3-Nitrophenyl)piperidine-2,6-dione chemical structure, C11H10N2O4, CAS 81305-71-7
1-(3-Nitrophenyl)piperidine-2,6-dione
CAS 81305-71-7C11H10N2O4
N-(P-Tolyl)glutarimide chemical structure, C12H13NO2, CAS 81305-69-3
N-(P-Tolyl)glutarimide
CAS 81305-69-3C12H13NO2
1-(3-Chlorophenyl)azaperhydroine-2,6-dione chemical structure, C11H10ClNO2, CAS 392720-92-2
1-(3-Chlorophenyl)azaperhydroine-2,6-dione
CAS 392720-92-2C11H10ClNO2
1-(4-Aminophenyl)piperidine-2,6-dione chemical structure, C11H12N2O2, CAS 444003-01-4
1-(4-Aminophenyl)piperidine-2,6-dione
CAS 444003-01-4C11H12N2O2
1-(4-Nitrophenyl)piperidine-2,6-dione chemical structure, C11H10N2O4, CAS 139776-02-6
1-(4-Nitrophenyl)piperidine-2,6-dione
CAS 139776-02-6C11H10N2O4
N-[3-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N'-methylurea chemical structure, C15H19N3O3, CAS 88011-48-7
N-[3-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N'-methylurea
CAS 88011-48-7C15H19N3O3
N-[3-(3,3-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N'-methylurea chemical structure, C15H19N3O3, CAS 88011-50-1
N-[3-(3,3-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N'-methylurea
CAS 88011-50-1C15H19N3O3
N'-[3-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N,N-dimethylurea chemical structure, C16H21N3O3, CAS 88011-52-3
N'-[3-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)phenyl]-N,N-dimethylurea
CAS 88011-52-3C16H21N3O3
3-(2,6-Dioxopiperidin-1-yl)benzoic acid chemical structure, C12H11NO4, CAS 140213-08-7
3-(2,6-Dioxopiperidin-1-yl)benzoic acid
CAS 140213-08-7C12H11NO4
5-(2,6-Dioxopiperidin-1-yl)-2-methoxybenzenesulfonyl chloride chemical structure, C12H12ClNO5S, CAS 927999-81-3
5-(2,6-Dioxopiperidin-1-yl)-2-methoxybenzenesulfonyl chloride
CAS 927999-81-3C12H12ClNO5S
4-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)benzoic acid chemical structure, C14H15NO4, CAS 946699-70-3
4-(4,4-Dimethyl-2,6-dioxopiperidin-1-yl)benzoic acid
CAS 946699-70-3C14H15NO4
1-(3-Aminophenyl)-4,4-dimethylpiperidine-2,6-dione chemical structure, C13H16N2O2, CAS 88011-47-6
1-(3-Aminophenyl)-4,4-dimethylpiperidine-2,6-dione
CAS 88011-47-6C13H16N2O2
Ethyl 3-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate chemical structure, C16H19NO4, CAS 952183-63-0
Ethyl 3-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate
CAS 952183-63-0C16H19NO4
Methyl 3-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate chemical structure, C15H17NO4, CAS 1034736-87-2
Methyl 3-(4,4-dimethyl-2,6-dioxopiperidin-1-yl)benzoate
CAS 1034736-87-2C15H17NO4