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Murcko scaffold

Ring system with 3 rings and 21 atoms

16 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
16
With full pages
4
Scaffold SMILES

C(=Nn1cnnc1)c1ccc(OCc2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C(=Nn1cnnc1)c1ccc(OCc2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 16 of 16 chemicals

N-{(E)-[4-(benzyloxy)phenyl]methylidene}-4H-1,2,4-triazol-4-amine chemical structure, C16H14N4O, CAS 301203-29-2
N-{(E)-[4-(benzyloxy)phenyl]methylidene}-4H-1,2,4-triazol-4-amine
CAS 301203-29-2C16H14N4O
N-[(E)-{4-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C16H12ClFN4O, CAS 5674-92-0
N-[(E)-{4-[(2-Chloro-6-fluorobenzyl)oxy]phenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 5674-92-0C16H12ClFN4O
N-[(E)-{3-Bromo-4-[(2,4-dichlorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H13BrCl2N4O2, CAS 328960-89-0
N-[(E)-{3-Bromo-4-[(2,4-dichlorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 328960-89-0C17H13BrCl2N4O2
2-[[2-Iodo-6-methoxy-4-[(E)-1,2,4-triazol-4-yliminomethyl]phenoxy]methyl]benzonitrile chemical structure, C18H14IN5O2, CAS 347397-32-4
2-[[2-Iodo-6-methoxy-4-[(E)-1,2,4-triazol-4-yliminomethyl]phenoxy]methyl]benzonitrile
CAS 347397-32-4C18H14IN5O2
1-[4-[(2-Fluorophenyl)methoxy]phenyl]-N-(1,2,4-triazol-4-yl)methanimine chemical structure, C16H13FN4O, CAS 301348-45-8
1-[4-[(2-Fluorophenyl)methoxy]phenyl]-N-(1,2,4-triazol-4-yl)methanimine
CAS 301348-45-8C16H13FN4O
3-({2-Methoxy-4-[(E)-(4H-1,2,4-triazol-4-ylimino)methyl]phenoxy}methyl)benzoic acid chemical structure, C18H16N4O4, CAS 428837-56-3
3-({2-Methoxy-4-[(E)-(4H-1,2,4-triazol-4-ylimino)methyl]phenoxy}methyl)benzoic acid
CAS 428837-56-3C18H16N4O4
N-{3-Methoxy-4-[(4-methylbenzyl)oxy]benzylidene}-4H-1,2,4-triazol-4-amine chemical structure, C18H18N4O2, CAS 311798-38-6
N-{3-Methoxy-4-[(4-methylbenzyl)oxy]benzylidene}-4H-1,2,4-triazol-4-amine
CAS 311798-38-6C18H18N4O2
1-[4-[(4-Fluorophenyl)methoxy]phenyl]-N-(1,2,4-triazol-4-yl)methanimine chemical structure, C16H13FN4O, CAS 301348-48-1
1-[4-[(4-Fluorophenyl)methoxy]phenyl]-N-(1,2,4-triazol-4-yl)methanimine
CAS 301348-48-1C16H13FN4O
N-[(E)-{4-[(2-Fluorobenzyl)oxy]-3-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H15FN4O2, CAS 301807-76-1
N-[(E)-{4-[(2-Fluorobenzyl)oxy]-3-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 301807-76-1C17H15FN4O2
4-[[2-Methoxy-4-[(E)-1,2,4-triazol-4-yliminomethyl]phenoxy]methyl]benzoic acid chemical structure, C18H16N4O4, CAS 681005-56-1
4-[[2-Methoxy-4-[(E)-1,2,4-triazol-4-yliminomethyl]phenoxy]methyl]benzoic acid
CAS 681005-56-1C18H16N4O4
N-[(E)-{3-Chloro-4-[(2-fluorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H14ClFN4O2, CAS 302823-83-2
N-[(E)-{3-Chloro-4-[(2-fluorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 302823-83-2C17H14ClFN4O2
N-{(E)-[4-(benzyloxy)-2-bromo-5-methoxyphenyl]methylidene}-4H-1,2,4-triazol-4-amine chemical structure, C17H15BrN4O2, CAS 393127-26-9
N-{(E)-[4-(benzyloxy)-2-bromo-5-methoxyphenyl]methylidene}-4H-1,2,4-triazol-4-amine
CAS 393127-26-9C17H15BrN4O2
N-[(E)-{2-Bromo-4-[(4-chlorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H14BrClN4O2, CAS 393127-21-4
N-[(E)-{2-Bromo-4-[(4-chlorobenzyl)oxy]-5-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 393127-21-4C17H14BrClN4O2
N-[(E)-{3-Methoxy-4-[(4-nitrobenzyl)oxy]phenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H15N5O4, CAS 690671-25-1
N-[(E)-{3-Methoxy-4-[(4-nitrobenzyl)oxy]phenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 690671-25-1C17H15N5O4
N-[(E)-{4-[(2-Chlorobenzyl)oxy]-3-ethoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C18H17ClN4O2, CAS 302565-25-9
N-[(E)-{4-[(2-Chlorobenzyl)oxy]-3-ethoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 302565-25-9C18H17ClN4O2
N-[(E)-{4-[(2-Chlorobenzyl)oxy]-3-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine chemical structure, C17H15ClN4O2, CAS 301811-47-2
N-[(E)-{4-[(2-Chlorobenzyl)oxy]-3-methoxyphenyl}methylidene]-4H-1,2,4-triazol-4-amine
CAS 301811-47-2C17H15ClN4O2