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Murcko scaffold

5-Benzoylpyrimidine scaffold

84 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
84
With full pages
3
Scaffold SMILES

O=C(c1ccccc1)c1cncnc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 5-Benzoylpyrimidine page
Murcko scaffold O=C(c1ccccc1)c1cncnc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 84 chemicals

(2,4-Diethoxypyrimidin-5-yl)(phenyl)methanone chemical structure, C15H16N2O3, CAS 92580-28-4
(2,4-Diethoxypyrimidin-5-yl)(phenyl)methanone
CAS 92580-28-4C15H16N2O3
(2,4-Diethoxypyrimidin-5-yl)(4-fluorophenyl)methanone chemical structure, C15H15FN2O3, CAS 1543-17-5
(2,4-Diethoxypyrimidin-5-yl)(4-fluorophenyl)methanone
CAS 1543-17-5C15H15FN2O3
(2,4-Diethoxypyrimidin-5-yl)-(4-methylphenyl)methanone chemical structure, C16H18N2O3, CAS 93019-73-9
(2,4-Diethoxypyrimidin-5-yl)-(4-methylphenyl)methanone
CAS 93019-73-9C16H18N2O3
Methanone, (2-amino-5-pyrimidinyl)(2-hydroxyphenyl)- chemical structure, C11H9N3O2, CAS 64469-20-1
Methanone, (2-amino-5-pyrimidinyl)(2-hydroxyphenyl)-
CAS 64469-20-1C11H9N3O2
Methanone, (2-hydroxyphenyl)(2-methyl-5-pyrimidinyl)- chemical structure, C12H10N2O2, CAS 64469-21-2
Methanone, (2-hydroxyphenyl)(2-methyl-5-pyrimidinyl)-
CAS 64469-21-2C12H10N2O2
2-(5-Pyrimidinylcarbonyl)benzoic acid chemical structure, C12H8N2O3, CAS 153078-02-5
2-(5-Pyrimidinylcarbonyl)benzoic acid
CAS 153078-02-5C12H8N2O3
(4-Amino-2-(ethylthio)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone chemical structure, C14H13F2N3O2S, CAS 741713-37-1
(4-Amino-2-(ethylthio)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone
CAS 741713-37-1C14H13F2N3O2S
[4-Amino-2-(ethylthio)-5-pyrimidinyl](3-fluorophenyl)methanone chemical structure, C13H12FN3OS, CAS 741712-37-8
[4-Amino-2-(ethylthio)-5-pyrimidinyl](3-fluorophenyl)methanone
CAS 741712-37-8C13H12FN3OS
(4-Amino-2-ethanesulfonyl-pyrimidin-5-yl)-(3-fluoro-phenyl)-methanone chemical structure, C13H12FN3O3S, CAS 741712-38-9
(4-Amino-2-ethanesulfonyl-pyrimidin-5-yl)-(3-fluoro-phenyl)-methanone
CAS 741712-38-9C13H12FN3O3S
(4-Amino-2-(ethylsulfonyl)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone chemical structure, C14H13F2N3O4S, CAS 741713-38-2
(4-Amino-2-(ethylsulfonyl)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone
CAS 741713-38-2C14H13F2N3O4S
(2-Hydroxyphenyl)-pyrimidin-5-yl-methanone chemical structure, C11H8N2O2, CAS 59496-85-4
(2-Hydroxyphenyl)-pyrimidin-5-yl-methanone
CAS 59496-85-4C11H8N2O2
4-Pyrimidinecarboxylic acid, 2-amino-5-benzoyl-, methyl ester chemical structure, C13H11N3O3, CAS 62328-08-9
4-Pyrimidinecarboxylic acid, 2-amino-5-benzoyl-, methyl ester
CAS 62328-08-9C13H11N3O3
(2,4-Dimethylpyrimidin-5-yl)(2-hydroxyphenyl)methanone chemical structure, C13H12N2O2, CAS 31964-96-2
(2,4-Dimethylpyrimidin-5-yl)(2-hydroxyphenyl)methanone
CAS 31964-96-2C13H12N2O2
5-Benzoylpyrimidine chemical structure, C11H8N2O, CAS 92674-40-3
5-Benzoylpyrimidine
CAS 92674-40-3C11H8N2O
(2-Aminopyrimidin-5-yl)(2-hydroxy-4-methylphenyl)methanone chemical structure, C12H11N3O2, CAS 95664-45-2
(2-Aminopyrimidin-5-yl)(2-hydroxy-4-methylphenyl)methanone
CAS 95664-45-2C12H11N3O2
5-Benzoyl-2-(methylthio)-4-pyrimidinecarboxylic acid chemical structure, C13H10N2O3S, CAS 111252-99-4
5-Benzoyl-2-(methylthio)-4-pyrimidinecarboxylic acid
CAS 111252-99-4C13H10N2O3S
[2-(Methylthio)-5-pyrimidinyl]phenylmethanone chemical structure, C12H10N2OS, CAS 110099-97-3
[2-(Methylthio)-5-pyrimidinyl]phenylmethanone
CAS 110099-97-3C12H10N2OS
(4-Methoxyphenyl)(2-(methylthio)-5-pyrimidinyl)methanone chemical structure, C13H12N2O2S, CAS 111253-05-5
(4-Methoxyphenyl)(2-(methylthio)-5-pyrimidinyl)methanone
CAS 111253-05-5C13H12N2O2S
(4-Chlorophenyl)(pyrimidin-5-yl)methanone chemical structure, C11H7ClN2O, CAS 103686-55-1
(4-Chlorophenyl)(pyrimidin-5-yl)methanone
CAS 103686-55-1C11H7ClN2O
(2-Chloro-5-pyrimidinyl)phenylmethanone chemical structure, C11H7ClN2O, CAS 110100-02-2
(2-Chloro-5-pyrimidinyl)phenylmethanone
CAS 110100-02-2C11H7ClN2O
5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine chemical structure, C14H16N4O4, CAS 30806-86-1
5-(3,4,5-Trimethoxybenzoyl)-2,4-pyrimidinediamine
CAS 30806-86-1C14H16N4O4
Methanone,(2,4-dichlorophenyl)-5-pyrimidinyl- chemical structure, C11H6Cl2N2O, CAS 108025-04-3
Methanone,(2,4-dichlorophenyl)-5-pyrimidinyl-
CAS 108025-04-3C11H6Cl2N2O
(2,4-Dichloropyrimidin-5-yl)(phenyl)methanone chemical structure, C11H6Cl2N2O, CAS 871254-59-0
(2,4-Dichloropyrimidin-5-yl)(phenyl)methanone
CAS 871254-59-0C11H6Cl2N2O
Methanone,5-pyrimidinyl[3-(trifluoromethyl)phenyl]- chemical structure, C12H7F3N2O, CAS 174813-00-4
Methanone,5-pyrimidinyl[3-(trifluoromethyl)phenyl]-
CAS 174813-00-4C12H7F3N2O