Murcko scaffold
Ring system with 6 rings and 23 atoms
47 chemicals on CompoundList share this ring system.
- Rings
- 6
- Scaffold atoms
- 23
- Chemicals
- 47
- With full pages
- 13
Scaffold SMILES
O=C1CCC2C3Cc4cccc5c4C2(CCN3CC2CC2)C1O5
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 47 of 47 chemicals
Naltrexone
CAS 16590-41-3C20H23NO4
Conorfone
CAS 72060-05-0C23H29NO3
Methylnaltrexone bromide
CAS 73232-52-7C21H26BrNO4
Methylnaltrexone
CAS 83387-25-1C21H26NO4+
3-Desoxynaltrexone
CAS 152659-61-5C20H23NO3
Naltrexone hydrochloride
CAS 16676-29-2C20H24ClNO4
3-Methoxynaltrexone
CAS 16617-07-5C21H25NO4
Naltrexone 14-acetate
CAS 121962-99-0C22H25NO5
Naltrexone 3-acetate
CAS 111129-14-7C22H25NO5
14-(Bromoacetamido)-7,8-dihydro-N-(cyclopropylmethy)normorphinone
CAS 151061-15-3C22H25BrN2O4
Conorphone hydrochloride
CAS 70865-14-4C23H30ClNO3
3-Desoxy-3-carboxamidonaltrexone
CAS 421552-35-4C21H24N2O4
Morphinan-6-one, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-, (5alpha)-, mixt. with 1-(3-chlorophenyl)-2-((1,1-dimethylethyl)amino)-1-propanone
CAS 1201668-08-7C33H41ClN2O5
(+)-Naltrexone
CAS 91464-13-0C20H23NO4
Naltrexone N-oxide
CAS 112269-62-2C20H23NO5
(5a)-17-(Cyclopropylmethyl)-14-hydroxy-6-oxo-4,5-epoxymorphinan-3-yl trifluoromethanesulfonate
CAS 205375-23-1C21H22F3NO6S
Naltrexone impurity 79
CAS 207732-98-7C21H22N2O3
Methylnaltrexone bromide, (17S)-
CAS 916045-21-1C21H26BrNO4
Methylnaltrexone, (17S)-
CAS 916045-22-2C21H26NO4+
![Methylnaltrexone [VANDF] chemical structure, C21H26NO4+, CAS 916055-93-1](/s/JVLBPIPGETUEET-WIXLDOGYSA-O.svg)
Methylnaltrexone [VANDF]
CAS 916055-93-1C21H26NO4+
Naltrexone hydrochloride dihydrate
CAS 850808-02-5C20H28ClNO6
14-Chloroacetylnaltrexone
CAS 82975-76-6C22H24ClNO5
N,O-Dimethyl-naltrexone bromide
CAS 1005410-37-6C22H28BrNO4
Naltrexone methiodide
CAS 73232-53-8C21H26INO4
- Naltrexone-d31261080-26-5C20H23NO4
- (5alpha)-17-(Cyclopropylmethyl)-14-hydroxy-6-oxo-4,5-epoxymorphinan-3-yl 2-methylpropanoate861238-38-2C24H29NO5
- 17-(Cyclopropylmethyl)-14-hydroxy-6-oxo-5alpha-4,5-epoxymorphinan-3-yl 3-methylbutanoate861238-36-0C25H31NO5
- Morphine/naltrexone850636-73-6C54H63N3O14S
- Naltrexone benzoate152659-56-8C27H29NO6
- 10-Hydroxy naltrexone methyl ether96445-12-4C21H25NO5
- 8beta-hydroxy naltrexone2139257-33-1C20H23NO5
- (5alpha)-17-(Cyclopropylmethyl)-3,10,14-trihydroxy-4,5-epoxymorphinan-6-one604767-82-0C20H23NO5
- O-Isobutyryl N-methyl naltrexone iodide1048360-09-3C25H32INO5
- Naltrexone-d42070009-29-7C20H23NO4
- SequestOx850636-71-4C38H46Cl2N2O8
- Morphine sulfate, naltrexone hydrochloride1131418-84-2C54H64ClN3O14S
- Methylnaltrexone D3 (bromide)1131456-47-7C21H26BrNO4
- 2-Hydroxy-3-methoxynaltrexone67829-18-9C21H25NO5
- 1 suppliers10alpha-hydroxy naltrexone2397651-97-5C20H23NO5
- 2-Chloro-10alpha-hydroxynaltrexone (>85%)619331-76-9C20H22ClNO5
- (5|A)-17-(Cyclopropylmethyl)-4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-6-oxomorphinanium Iodide1360001-83-7C22H28INO4
- (5a,17S)-3-(Acetyloxy)-17-(cyclopropylmethyl)-4,5-epoxy-14-hydroxy-17-methyl-6-oxomorphinanium Bromide1252784-80-7C23H28BrNO5
- N-Methyl naltrexone sulfate1067643-19-9C21H25NO7S
- Naltrexone-O-ethyl Carbonate836602-51-8C23H27NO6
- (+)-Naltrexone hydrochloride114274-32-7C20H24ClNO4
- Morphinanium, 17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxy-17-methyl-6-oxo-, inner salt, hydrate (1:3), (5I+/-)-1013912-21-4C21H31NO7
- 7-Dihydroxy Methylnaltrexone Bromide DISCONTINUED1005410-42-3C21H26BrNO6
Related scaffolds
Same ring framework with different atoms or bond orders
