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Murcko scaffold

Ring system with 6 rings and 23 atoms

10 chemicals on CompoundList share this ring system.

Rings
6
Scaffold atoms
23
Chemicals
10
With full pages
3
Scaffold SMILES

C=C1CCC2C3Cc4cccc5c4C2(CCN3CC2CC2)C1O5

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold C=C1CCC2C3Cc4cccc5c4C2(CCN3CC2CC2)C1O5

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 10 of 10 chemicals

Nalmefene chemical structure, C21H25NO3, CAS 55096-26-9
Nalmefene
CAS 55096-26-9C21H25NO3
Nalmefene hydrochloride chemical structure, C21H26ClNO3, CAS 58895-64-0
Nalmefene hydrochloride
CAS 58895-64-0C21H26ClNO3
(4R,4aS,7aS,12bS)-3-(Cyclopropylmethyl)-9-methoxy-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-ol chemical structure, C22H27NO3, CAS 144265-45-2
(4R,4aS,7aS,12bS)-3-(Cyclopropylmethyl)-9-methoxy-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinolin-4a-ol
CAS 144265-45-2C22H27NO3
Nalmefene methiodide chemical structure, C22H28INO3, CAS 136440-71-6
Nalmefene methiodide
CAS 136440-71-6C22H28INO3
Nalmefene hydrochloride dihydrate chemical structure, C21H30ClNO5, CAS 1228646-70-5
Nalmefene hydrochloride dihydrate
CAS 1228646-70-5C21H30ClNO5
Nalmefene methiodide chemical structure, C22H28INO3
Nalmefene methiodide
C22H28INO3
Nalmefene impurity 23 chemical structure, C21H25NO3, CAS 131378-67-1
Nalmefene impurity 23
CAS 131378-67-1C21H25NO3
Nalmefene hydrochloride monohydrate chemical structure, C21H28ClNO4, CAS 1228646-72-7
Nalmefene hydrochloride monohydrate
CAS 1228646-72-7C21H28ClNO4
17-(Cyclopropylmethyl)-6-methylidene-5alpha-4,5-epoxymorphinan-3-ol chemical structure, C21H25NO2, CAS 663921-37-7
17-(Cyclopropylmethyl)-6-methylidene-5alpha-4,5-epoxymorphinan-3-ol
CAS 663921-37-7C21H25NO2
Naltrexone impurity 32 chemical structure, C21H25NO4, CAS 112242-15-6
Naltrexone impurity 32
CAS 112242-15-6C21H25NO4