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Murcko scaffold

Naphthalen-2(1H)-one scaffold

56 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
56
With full pages
3
Scaffold SMILES

O=C1C=Cc2ccccc2C1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Naphthalen-2(1H)-one page
Murcko scaffold O=C1C=Cc2ccccc2C1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 56 chemicals

(1R)-1-Hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-2(1H)-naphthalenone chemical structure, C16H20O3, CAS 56362-72-2
(1R)-1-Hydroxy-7-methoxy-1,6-dimethyl-4-(1-methylethyl)-2(1H)-naphthalenone
CAS 56362-72-2C16H20O3
(1R)-1,7-Dihydroxy-1,6-dimethyl-4-(1-methylethyl)-2(1H)-naphthalenone chemical structure, C15H18O3, CAS 41653-72-9
(1R)-1,7-Dihydroxy-1,6-dimethyl-4-(1-methylethyl)-2(1H)-naphthalenone
CAS 41653-72-9C15H18O3
1-Hydroxy-7-methoxy-1,5-dimethyl-3-(propan-2-yl)naphthalen-2(1H)-one chemical structure, C16H20O3, CAS 60135-23-1
1-Hydroxy-7-methoxy-1,5-dimethyl-3-(propan-2-yl)naphthalen-2(1H)-one
CAS 60135-23-1C16H20O3
1-(Chloromethyl)-1-methylnaphthalen-2-one chemical structure, C12H11ClO, CAS 5452-44-8
1-(Chloromethyl)-1-methylnaphthalen-2-one
CAS 5452-44-8C12H11ClO
1-(Dichloromethyl)-1-methylnaphthalen-2-one chemical structure, C12H10Cl2O, CAS 6947-67-7
1-(Dichloromethyl)-1-methylnaphthalen-2-one
CAS 6947-67-7C12H10Cl2O
1-Hydroxy-1-methylnaphthalen-2(1H)-one chemical structure, C11H10O2, CAS 57565-12-5
1-Hydroxy-1-methylnaphthalen-2(1H)-one
CAS 57565-12-5C11H10O2
2(1H)-Naphthalenone, 3-bromo-1,1-dimethyl- chemical structure, C12H11BrO, CAS 105282-76-6
2(1H)-Naphthalenone, 3-bromo-1,1-dimethyl-
CAS 105282-76-6C12H11BrO
3-Hydroxy-1,1-dimethylnaphthalen-2-one chemical structure, C12H12O2, CAS 30013-78-6
3-Hydroxy-1,1-dimethylnaphthalen-2-one
CAS 30013-78-6C12H12O2
2(1H)-Naphthalenone, 4-methyl chemical structure, C11H10O, CAS 713072-64-1
2(1H)-Naphthalenone, 4-methyl
CAS 713072-64-1C11H10O
2(1H)-Naphthalenone, 1-methyl-1-(2-propynyl)- chemical structure, C14H12O, CAS 41389-92-8
2(1H)-Naphthalenone, 1-methyl-1-(2-propynyl)-
CAS 41389-92-8C14H12O
1,1-Difluoro-1H-naphthalene-2-one chemical structure, C10H6F2O, CAS 51417-64-2
1,1-Difluoro-1H-naphthalene-2-one
CAS 51417-64-2C10H6F2O
Sassafrin D chemical structure, C27H32O8, CAS 848948-44-7
Sassafrin D
CAS 848948-44-7C27H32O8
Naphthalen-2(1H)-one chemical structure, C10H8O, CAS 136156-72-4
Naphthalen-2(1H)-one
CAS 136156-72-4C10H8O
3-Hydroxynaphthalen-1(4H)-one chemical structure, C10H8O2, CAS 748103-97-1
3-Hydroxynaphthalen-1(4H)-one
CAS 748103-97-1C10H8O2
2(1H)-Naphthalenone, 1-(1,1-dimethylethyl)-3-hydroxy- chemical structure, C14H16O2, CAS 61601-22-7
2(1H)-Naphthalenone, 1-(1,1-dimethylethyl)-3-hydroxy-
CAS 61601-22-7C14H16O2
1-Ethyl-1-hydroperoxynaphthalen-2(1H)-one chemical structure, C12H12O3, CAS 62681-44-1
1-Ethyl-1-hydroperoxynaphthalen-2(1H)-one
CAS 62681-44-1C12H12O3
1,4-Dihydroxy-1-(propan-2-yl)naphthalen-2(1H)-one chemical structure, C13H14O3, CAS 64605-95-4
1,4-Dihydroxy-1-(propan-2-yl)naphthalen-2(1H)-one
CAS 64605-95-4C13H14O3
4-Hydroxy-1,1,8-trimethyl-3-nitronaphthalen-2(1H)-one chemical structure, C13H13NO4, CAS 63228-94-4
4-Hydroxy-1,1,8-trimethyl-3-nitronaphthalen-2(1H)-one
CAS 63228-94-4C13H13NO4
1,1-Dimethylnaphthalen-2(1H)-one chemical structure, C12H12O, CAS 23230-52-6
1,1-Dimethylnaphthalen-2(1H)-one
CAS 23230-52-6C12H12O
6-tert-Butyl-1,1-dichloronaphthalen-2(1H)-one chemical structure, C14H14Cl2O, CAS 86044-32-8
6-tert-Butyl-1,1-dichloronaphthalen-2(1H)-one
CAS 86044-32-8C14H14Cl2O
1,1,3-Trichloronaphthalen-2(1H)-one chemical structure, C10H5Cl3O, CAS 31337-01-6
1,1,3-Trichloronaphthalen-2(1H)-one
CAS 31337-01-6C10H5Cl3O
1,7-Dihydroxy-1,6-dimethyl-4-(propan-2-yl)-1,2-dihydronaphthalen-2-one chemical structure, C15H18O3, CAS 87900-51-4
1,7-Dihydroxy-1,6-dimethyl-4-(propan-2-yl)-1,2-dihydronaphthalen-2-one
CAS 87900-51-4C15H18O3
1-Fluoro-1-(trifluoromethyl)naphthalen-2(1H)-one chemical structure, C11H6F4O, CAS 63418-30-4
1-Fluoro-1-(trifluoromethyl)naphthalen-2(1H)-one
CAS 63418-30-4C11H6F4O
1-Hydroxy-1-propylnaphthalen-2(1H)-one chemical structure, C13H14O2, CAS 57565-26-1
1-Hydroxy-1-propylnaphthalen-2(1H)-one
CAS 57565-26-1C13H14O2