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Murcko scaffold

Ring system with 4 rings and 26 atoms

12 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
26
Chemicals
12
With full pages
5
Scaffold SMILES

O=C(Nc1ccccc1)c1ccc2c(c1)C(=O)N(Cc1ccco1)C2=O

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1ccccc1)c1ccc2c(c1)C(=O)N(Cc1ccco1)C2=O

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 12 of 12 chemicals

4-[[2-(Furan-2-ylmethyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acid chemical structure, C21H14N2O6, CAS 666710-85-6
4-[[2-(Furan-2-ylmethyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acid
CAS 666710-85-6C21H14N2O6
N-(2-Chlorophenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C20H13ClN2O4, CAS 666711-13-3
N-(2-Chlorophenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide
CAS 666711-13-3C20H13ClN2O4
2-(2-Furylmethyl)-N-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolinecarboxamide chemical structure, C20H14N2O5, CAS 666710-86-7
2-(2-Furylmethyl)-N-(4-hydroxyphenyl)-1,3-dioxo-5-isoindolinecarboxamide
CAS 666710-86-7C20H14N2O5
5-Bromo-2-({[2-(furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid chemical structure, C21H13BrN2O6, CAS 712322-75-3
5-Bromo-2-({[2-(furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoic acid
CAS 712322-75-3C21H13BrN2O6
N-(5-Chloro-2-hydroxyphenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C20H13ClN2O5, CAS 712323-83-6
N-(5-Chloro-2-hydroxyphenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide
CAS 712323-83-6C20H13ClN2O5
N-(2-Ethoxyphenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C22H18N2O5, CAS 712326-09-5
N-(2-Ethoxyphenyl)-2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carboxamide
CAS 712326-09-5C22H18N2O5
2-(Furan-2-ylmethyl)-N-(2-hydroxy-5-methylphenyl)-1,3-dioxoisoindole-5-carboxamide chemical structure, C21H16N2O5, CAS 712333-78-3
2-(Furan-2-ylmethyl)-N-(2-hydroxy-5-methylphenyl)-1,3-dioxoisoindole-5-carboxamide
CAS 712333-78-3C21H16N2O5
2-({[2-(2-Furylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)-5-hydroxybenzoic acid chemical structure, C21H14N2O7, CAS 712335-73-4
2-({[2-(2-Furylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)-5-hydroxybenzoic acid
CAS 712335-73-4C21H14N2O7
5-Chloro-2-[[2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acid chemical structure, C21H13ClN2O6, CAS 712338-35-7
5-Chloro-2-[[2-(furan-2-ylmethyl)-1,3-dioxoisoindole-5-carbonyl]amino]benzoic acid
CAS 712338-35-7C21H13ClN2O6
2-({[2-(Furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)-4,5-dimethoxybenzoic acid chemical structure, C23H18N2O8, CAS 712344-17-7
2-({[2-(Furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)-4,5-dimethoxybenzoic acid
CAS 712344-17-7C23H18N2O8
5-({[2-(Furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzene-1,3-dicarboxylic acid chemical structure, C22H14N2O8, CAS 709009-68-7
5-({[2-(Furan-2-ylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzene-1,3-dicarboxylic acid
CAS 709009-68-7C22H14N2O8
Methyl 2-({[2-(2-furylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoate chemical structure, C22H16N2O6, CAS 832118-96-4
Methyl 2-({[2-(2-furylmethyl)-1,3-dioxo-2,3-dihydro-1H-isoindol-5-yl]carbonyl}amino)benzoate
CAS 832118-96-4C22H16N2O6