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Murcko scaffold

1-Phenyl-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine scaffold

9 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
9
With full pages
4
Scaffold SMILES

c1ccc(-n2ncc3c(NCc4ccccn4)ncnc32)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1-Phenyl-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine page
Murcko scaffold c1ccc(-n2ncc3c(NCc4ccccn4)ncnc32)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 9 of 9 chemicals

1-(4-Chlorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C17H13ClN6, CAS 393821-36-8
1-(4-Chlorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393821-36-8C17H13ClN6
1-(3-Methylphenyl)-N-(2-pyridinylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine chemical structure, C18H16N6, CAS 393820-44-5
1-(3-Methylphenyl)-N-(2-pyridinylmethyl)-4-pyrazolo[3,4-d]pyrimidinamine
CAS 393820-44-5C18H16N6
1-(2,4-Dimethylphenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H18N6, CAS 393822-77-0
1-(2,4-Dimethylphenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393822-77-0C19H18N6
1-Phenyl-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C17H14N6, CAS 393820-03-6
1-Phenyl-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-03-6C17H14N6
1-(3,4-Dichlorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C17H12Cl2N6, CAS 872621-73-3
1-(3,4-Dichlorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 872621-73-3C17H12Cl2N6
1-(3,4-Difluorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C17H12F2N6, CAS 920485-34-3
1-(3,4-Difluorophenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 920485-34-3C17H12F2N6
[1-(3-Chloro-4-methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-pyridylmethyl)ami ne chemical structure, C18H15ClN6, CAS 890895-70-2
[1-(3-Chloro-4-methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-pyridylmethyl)ami ne
CAS 890895-70-2C18H15ClN6
1-(3,4-Dimethylphenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H18N6, CAS 872623-10-4
1-(3,4-Dimethylphenyl)-N-(pyridin-2-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 872623-10-4C19H18N6
[1-(2-Methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-pyridylmethyl)amine chemical structure, C18H16N6, CAS 1207047-32-2
[1-(2-Methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl](2-pyridylmethyl)amine
CAS 1207047-32-2C18H16N6