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Murcko scaffold

Ring system with 4 rings and 23 atoms

44 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
44
With full pages
1
Scaffold SMILES

c1ccc(CSc2ncnc3c2nnn3-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CSc2ncnc3c2nnn3-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

7-(Benzylthio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C18H15N5OS, CAS 863500-72-5
7-(Benzylthio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863500-72-5C18H15N5OS
3-(4-Fluorophenyl)-7-[[4-(trifluoromethyl)phenyl]methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C18H11F4N5S, CAS 863460-50-8
3-(4-Fluorophenyl)-7-[[4-(trifluoromethyl)phenyl]methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-50-8C18H11F4N5S
7-(Benzylthio)-3-(p-tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C18H15N5S, CAS 863459-70-5
7-(Benzylthio)-3-(p-tolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863459-70-5C18H15N5S
7-[(4-Bromophenyl)methylsulfanyl]-3-(4-methylphenyl)triazolo[4,5-d]pyrimidine chemical structure, C18H14BrN5S, CAS 863459-73-8
7-[(4-Bromophenyl)methylsulfanyl]-3-(4-methylphenyl)triazolo[4,5-d]pyrimidine
CAS 863459-73-8C18H14BrN5S
7-(Benzylthio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C17H12FN5S, CAS 863460-38-2
7-(Benzylthio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863460-38-2C17H12FN5S
3-(4-Fluorophenyl)-7-[(3-fluorophenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C17H11F2N5S, CAS 863460-39-3
3-(4-Fluorophenyl)-7-[(3-fluorophenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-39-3C17H11F2N5S
7-((4-Fluorobenzyl)thio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C17H11F2N5S, CAS 863460-40-6
7-((4-Fluorobenzyl)thio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863460-40-6C17H11F2N5S
3-(4-Fluorophenyl)-7-[(2-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C18H14FN5S, CAS 863460-43-9
3-(4-Fluorophenyl)-7-[(2-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-43-9C18H14FN5S
7-[(4-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine chemical structure, C17H11ClFN5S, CAS 863460-36-0
7-[(4-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine
CAS 863460-36-0C17H11ClFN5S
3-(4-Fluorophenyl)-7-[(3-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C18H14FN5S, CAS 863460-45-1
3-(4-Fluorophenyl)-7-[(3-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-45-1C18H14FN5S
7-[(2-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine chemical structure, C17H11ClFN5S, CAS 863460-46-2
7-[(2-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine
CAS 863460-46-2C17H11ClFN5S
7-[(2,5-Dimethylphenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine chemical structure, C19H16FN5S, CAS 863460-47-3
7-[(2,5-Dimethylphenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine
CAS 863460-47-3C19H16FN5S
3-(4-Fluorophenyl)-7-[(4-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C18H14FN5S, CAS 863460-48-4
3-(4-Fluorophenyl)-7-[(4-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-48-4C18H14FN5S
3-(4-Fluorophenyl)-7-[[3-(trifluoromethyl)phenyl]methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C18H11F4N5S, CAS 863460-49-5
3-(4-Fluorophenyl)-7-[[3-(trifluoromethyl)phenyl]methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863460-49-5C18H11F4N5S
7-((2-Fluorobenzyl)thio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C17H11F2N5S, CAS 863460-52-0
7-((2-Fluorobenzyl)thio)-3-(4-fluorophenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863460-52-0C17H11F2N5S
7-[(3-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine chemical structure, C17H11ClFN5S, CAS 863460-53-1
7-[(3-Chlorophenyl)methylsulfanyl]-3-(4-fluorophenyl)triazolo[4,5-d]pyrimidine
CAS 863460-53-1C17H11ClFN5S
7-((3-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C18H14FN5OS, CAS 863500-73-6
7-((3-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863500-73-6C18H14FN5OS
7-((4-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C18H14FN5OS, CAS 863500-74-7
7-((4-Fluorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863500-74-7C18H14FN5OS
3-(4-Methoxyphenyl)-7-((2-methylbenzyl)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C19H17N5OS, CAS 863500-77-0
3-(4-Methoxyphenyl)-7-((2-methylbenzyl)thio)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863500-77-0C19H17N5OS
7-[(4-Chlorophenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine chemical structure, C18H14ClN5OS, CAS 863500-78-1
7-[(4-Chlorophenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine
CAS 863500-78-1C18H14ClN5OS
7-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine chemical structure, C18H13ClFN5OS, CAS 863500-79-2
7-[(2-Chloro-6-fluorophenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine
CAS 863500-79-2C18H13ClFN5OS
3-(4-Methoxyphenyl)-7-[(3-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine chemical structure, C19H17N5OS, CAS 863500-80-5
3-(4-Methoxyphenyl)-7-[(3-methylphenyl)methylsulfanyl]triazolo[4,5-d]pyrimidine
CAS 863500-80-5C19H17N5OS
7-((2-Chlorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine chemical structure, C18H14ClN5OS, CAS 863500-81-6
7-((2-Chlorobenzyl)thio)-3-(4-methoxyphenyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine
CAS 863500-81-6C18H14ClN5OS
7-[(2,5-Dimethylphenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine chemical structure, C20H19N5OS, CAS 863500-82-7
7-[(2,5-Dimethylphenyl)methylsulfanyl]-3-(4-methoxyphenyl)triazolo[4,5-d]pyrimidine
CAS 863500-82-7C20H19N5OS