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Murcko scaffold

Ring system with 4 rings and 23 atoms

47 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
47
With full pages
5
Scaffold SMILES

c1ccc(CNc2ncnc3c2cnn3-c2ccccc2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNc2ncnc3c2cnn3-c2ccccc2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 47 of 47 chemicals

N-Benzyl-1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C18H14ClN5, CAS 101716-06-7
N-Benzyl-1-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 101716-06-7C18H14ClN5
n-Benzyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H17N5, CAS 5401-50-3
n-Benzyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 5401-50-3C19H17N5
N-Benzyl-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H17N5O, CAS 393784-34-4
N-Benzyl-1-(4-methoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393784-34-4C19H17N5O
[1-(2,4-Dimethylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl]benzylamine chemical structure, C20H19N5, CAS 393784-36-6
[1-(2,4-Dimethylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl]benzylamine
CAS 393784-36-6C20H19N5
N-(3-Chlorobenzyl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16ClN5, CAS 393784-61-7
N-(3-Chlorobenzyl)-1-(m-tolyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393784-61-7C19H16ClN5
N-(2-Chlorobenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C18H14ClN5, CAS 393820-06-9
N-(2-Chlorobenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-06-9C18H14ClN5
N-(4-Methoxybenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H17N5O, CAS 393820-11-6
N-(4-Methoxybenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-11-6C19H17N5O
N-[(4-Methoxyphenyl)methyl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H19N5O, CAS 393820-66-1
N-[(4-Methoxyphenyl)methyl]-1-(3-methylphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-66-1C20H19N5O
[(2-Methoxyphenyl)methyl][1-(3-methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl]amin e chemical structure, C20H19N5O, CAS 393820-82-1
[(2-Methoxyphenyl)methyl][1-(3-methylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl]amin e
CAS 393820-82-1C20H19N5O
N-[(4-Fluorophenyl)methyl]-1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16FN5, CAS 393820-85-4
N-[(4-Fluorophenyl)methyl]-1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-85-4C19H16FN5
N-[(4-Fluorophenyl)methyl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16FN5O, CAS 393822-57-6
N-[(4-Fluorophenyl)methyl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393822-57-6C19H16FN5O
1-(4-Chlorophenyl)-N-[(4-methoxyphenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16ClN5O, CAS 393821-54-0
1-(4-Chlorophenyl)-N-[(4-methoxyphenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393821-54-0C19H16ClN5O
N-(2-Chlorobenzyl)-1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H18ClN5, CAS 393822-81-6
N-(2-Chlorobenzyl)-1-(2,4-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393822-81-6C20H18ClN5
N-[(2-Chlorophenyl)methyl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16ClN5O, CAS 393822-34-9
N-[(2-Chlorophenyl)methyl]-1-(4-methoxyphenyl)pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393822-34-9C19H16ClN5O
1-(4-Chlorophenyl)-N-(2-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16ClN5O, CAS 393821-64-2
1-(4-Chlorophenyl)-N-(2-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393821-64-2C19H16ClN5O
[1-(2,4-Dimethylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl][(2-methoxyphenyl)methyl] amine chemical structure, C21H21N5O, CAS 393822-92-9
[1-(2,4-Dimethylphenyl)pyrazolo[4,5-e]pyrimidin-4-yl][(2-methoxyphenyl)methyl] amine
CAS 393822-92-9C21H21N5O
1-(2,4-Dimethylphenyl)-N-[(4-methoxyphenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C21H21N5O, CAS 393822-86-1
1-(2,4-Dimethylphenyl)-N-[(4-methoxyphenyl)methyl]pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393822-86-1C21H21N5O
N-Benzyl-N-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H19N5, CAS 393844-95-6
N-Benzyl-N-methyl-1-(3-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393844-95-6C20H19N5
N-(2-Methoxybenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H17N5O, CAS 393820-16-1
N-(2-Methoxybenzyl)-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 393820-16-1C19H17N5O
N-(4-Fluorobenzyl)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C18H13F2N5, CAS 890896-18-1
N-(4-Fluorobenzyl)-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890896-18-1C18H13F2N5
N-Benzyl-N-ethyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H18FN5, CAS 890882-12-9
N-Benzyl-N-ethyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890882-12-9C20H18FN5
N-Benzyl-1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H16ClN5, CAS 890895-60-0
N-Benzyl-1-(3-chloro-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890895-60-0C19H16ClN5
1-(5-Chloro-2-methylphenyl)-N-(4-fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C19H15ClFN5, CAS 890937-22-1
1-(5-Chloro-2-methylphenyl)-N-(4-fluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890937-22-1C19H15ClFN5
1-(5-Chloro-2-methylphenyl)-N-(4-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine chemical structure, C20H18ClN5O, CAS 890937-61-8
1-(5-Chloro-2-methylphenyl)-N-(4-methoxybenzyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
CAS 890937-61-8C20H18ClN5O