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Murcko scaffold

Ring system with 4 rings and 23 atoms

44 chemicals on CompoundList share this ring system.

Rings
4
Scaffold atoms
23
Chemicals
44
With full pages
3
Scaffold SMILES

c1ccc(CNc2ccnc3c(-c4ccccc4)cnn23)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc(CNc2ccnc3c(-c4ccccc4)cnn23)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 44 of 44 chemicals

N-Benzyl-3-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H17ClN4, CAS 896810-61-0
N-Benzyl-3-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896810-61-0C20H17ClN4
5-tert-Butyl-N-[(2,4-dichlorophenyl)methyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H22Cl2N4, CAS 896814-38-3
5-tert-Butyl-N-[(2,4-dichlorophenyl)methyl]-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896814-38-3C23H22Cl2N4
N-Benzyl-2-methyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H24N4, CAS 896816-14-1
N-Benzyl-2-methyl-3-phenyl-5-propylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 896816-14-1C23H24N4
N-Benzyl-5-tert-butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H26N4, CAS 849922-31-2
N-Benzyl-5-tert-butyl-2-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 849922-31-2C24H26N4
N-Benzyl-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H24N4, CAS 896826-82-7
N-Benzyl-2-methyl-3-phenyl-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896826-82-7C23H24N4
N-Benzyl-5-tert-butyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H24N4, CAS 900271-95-6
N-Benzyl-5-tert-butyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900271-95-6C23H24N4
N-Benzyl-5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H23ClN4, CAS 896072-39-2
N-Benzyl-5-tert-butyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896072-39-2C23H23ClN4
N-Benzyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H20N4, CAS 877801-13-3
N-Benzyl-2,5-dimethyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877801-13-3C21H20N4
N-Benzyl-3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H19ClN4, CAS 862487-97-6
N-Benzyl-3-(4-chlorophenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 862487-97-6C21H19ClN4
N-Benzyl-5-tert-butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H25ClN4, CAS 877790-93-7
N-Benzyl-5-tert-butyl-3-(4-chlorophenyl)-2-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877790-93-7C24H25ClN4
3-(4-Chlorophenyl)-2,5-dimethyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H21ClN4, CAS 877797-04-1
3-(4-Chlorophenyl)-2,5-dimethyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 877797-04-1C22H21ClN4
5-tert-Butyl-3-(4-chlorophenyl)-2-methyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C25H27ClN4, CAS 877799-38-7
5-tert-Butyl-3-(4-chlorophenyl)-2-methyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 877799-38-7C25H27ClN4
N-Benzyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H22N4O, CAS 879583-06-9
N-Benzyl-3-(2-methoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 879583-06-9C22H22N4O
2,5-Dimethyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C22H22N4, CAS 850825-39-7
2,5-Dimethyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 850825-39-7C22H22N4
5-tert-Butyl-2-methyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C25H28N4, CAS 850721-58-3
5-tert-Butyl-2-methyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 850721-58-3C25H28N4
N-Benzyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C20H18N4, CAS 877781-88-9
N-Benzyl-5-methyl-3-phenylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 877781-88-9C20H18N4
5-Methyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H20N4, CAS 877804-89-2
5-Methyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 877804-89-2C21H20N4
5-tert-Butyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H26N4, CAS 896811-08-8
5-tert-Butyl-3-phenyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896811-08-8C24H26N4
5-tert-Butyl-3-(4-chlorophenyl)-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H25ClN4, CAS 896835-11-3
5-tert-Butyl-3-(4-chlorophenyl)-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 896835-11-3C24H25ClN4
2-Methyl-3-phenyl-N-(1-phenylethyl)-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C24H26N4, CAS 899397-22-9
2-Methyl-3-phenyl-N-(1-phenylethyl)-5-(propan-2-yl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 899397-22-9C24H26N4
N-Benzyl-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H20N4O, CAS 902013-86-9
N-Benzyl-3-(2-methoxyphenyl)-5-methylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 902013-86-9C21H20N4O
3-(2-Methoxyphenyl)-2,5-dimethyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H24N4O, CAS 902047-54-5
3-(2-Methoxyphenyl)-2,5-dimethyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 902047-54-5C23H24N4O
N-Benzyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C23H24N4O2, CAS 900872-98-2
N-Benzyl-3-(3,4-dimethoxyphenyl)-2,5-dimethylpyrazolo[1,5-a]pyrimidin-7-amine
CAS 900872-98-2C23H24N4O2
3-(4-Chlorophenyl)-5-methyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine chemical structure, C21H19ClN4, CAS 900281-51-8
3-(4-Chlorophenyl)-5-methyl-N-(1-phenylethyl)pyrazolo[1,5-a]pyrimidin-7-amine
CAS 900281-51-8C21H19ClN4