CompoundList
Sign in
Murcko scaffold

Ring system with 2 rings and 14 atoms

67 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
67
With full pages
14
Scaffold SMILES

O=c1cnnc(Nc2ccccc2)[nH]1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=c1cnnc(Nc2ccccc2)[nH]1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 67 chemicals

4-Amino-6-methyl-3-(phenylamino)-1,2,4-triazin-5(4H)-one chemical structure, C10H11N5O, CAS 77126-84-2
4-Amino-6-methyl-3-(phenylamino)-1,2,4-triazin-5(4H)-one
CAS 77126-84-2C10H11N5O
4-Amino-3-(4-chloroanilino)-6-methyl-4,5-dihydro-1,2,4-triazin-5-one chemical structure, C10H10ClN5O, CAS 22285-10-5
4-Amino-3-(4-chloroanilino)-6-methyl-4,5-dihydro-1,2,4-triazin-5-one
CAS 22285-10-5C10H10ClN5O
4-Amino-3-(4-methoxyanilino)-6-methyl-4,5-dihydro-1,2,4-triazin-5-one chemical structure, C11H13N5O2, CAS 96546-24-6
4-Amino-3-(4-methoxyanilino)-6-methyl-4,5-dihydro-1,2,4-triazin-5-one
CAS 96546-24-6C11H13N5O2
4-Amino-6-tert-butyl-3-(4-methylanilino)-1,2,4-triazin-5-one chemical structure, C14H19N5O, CAS 326003-98-9
4-Amino-6-tert-butyl-3-(4-methylanilino)-1,2,4-triazin-5-one
CAS 326003-98-9C14H19N5O
Methyl 4-((4-amino-6-(tert-butyl)-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)amino)benzoate chemical structure, C15H19N5O3, CAS 540771-15-1
Methyl 4-((4-amino-6-(tert-butyl)-5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)amino)benzoate
CAS 540771-15-1C15H19N5O3
6-tert-Butyl-3-[(4-nitrophenyl)amino]-1,2,4-triazin-5(4H)-one chemical structure, C13H15N5O3, CAS 898650-62-9
6-tert-Butyl-3-[(4-nitrophenyl)amino]-1,2,4-triazin-5(4H)-one
CAS 898650-62-9C13H15N5O3
3-((3,4-Dimethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O3, CAS 879639-89-1
3-((3,4-Dimethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one
CAS 879639-89-1C12H14N4O3
6-Methyl-3-(phenylamino)-1,2,4-triazin-5-ol chemical structure, C10H10N4O, CAS 6520-37-2
6-Methyl-3-(phenylamino)-1,2,4-triazin-5-ol
CAS 6520-37-2C10H10N4O
6-Methyl-3-[(2-methylphenyl)amino]-1,2,4-triazin-5(4H)-one chemical structure, C11H12N4O, CAS 453579-20-9
6-Methyl-3-[(2-methylphenyl)amino]-1,2,4-triazin-5(4H)-one
CAS 453579-20-9C11H12N4O
6-Methyl-3-[(3-methylphenyl)amino]-1,2,4-triazin-5-ol chemical structure, C11H12N4O, CAS 385373-13-7
6-Methyl-3-[(3-methylphenyl)amino]-1,2,4-triazin-5-ol
CAS 385373-13-7C11H12N4O
3-((2,5-Dimethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O3, CAS 450375-83-4
3-((2,5-Dimethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one
CAS 450375-83-4C12H14N4O3
3-(2,4-Dimethoxyanilino)-6-methyl-2H-1,2,4-triazin-5-one chemical structure, C12H14N4O3, CAS 443097-50-5
3-(2,4-Dimethoxyanilino)-6-methyl-2H-1,2,4-triazin-5-one
CAS 443097-50-5C12H14N4O3
3-[(4-Fluorophenyl)amino]-6-methyl-1,2,4-triazin-5-ol chemical structure, C10H9FN4O, CAS 443097-53-8
3-[(4-Fluorophenyl)amino]-6-methyl-1,2,4-triazin-5-ol
CAS 443097-53-8C10H9FN4O
6-Methyl-3-[(4-methylphenyl)amino]-1,2,4-triazin-5-ol chemical structure, C11H12N4O, CAS 77316-73-5
6-Methyl-3-[(4-methylphenyl)amino]-1,2,4-triazin-5-ol
CAS 77316-73-5C11H12N4O
6-(tert-Butyl)-3-[(4-chlorophenyl)amino]-1,2,4-triazin-5-ol chemical structure, C13H15ClN4O, CAS 443097-57-2
6-(tert-Butyl)-3-[(4-chlorophenyl)amino]-1,2,4-triazin-5-ol
CAS 443097-57-2C13H15ClN4O
3-(4-Isopropylanilino)-6-methyl-1,2,4-triazin-5(4H)-one chemical structure, C13H16N4O, CAS 450375-79-8
3-(4-Isopropylanilino)-6-methyl-1,2,4-triazin-5(4H)-one
CAS 450375-79-8C13H16N4O
3-((4-Butylphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one chemical structure, C14H18N4O, CAS 450375-80-1
3-((4-Butylphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one
CAS 450375-80-1C14H18N4O
3-((2-Ethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one chemical structure, C12H14N4O2, CAS 450375-72-1
3-((2-Ethoxyphenyl)amino)-6-methyl-1,2,4-triazin-5(4H)-one
CAS 450375-72-1C12H14N4O2
3-[(4-Methoxyphenyl)amino]-1,2,4-triazin-5-ol chemical structure, C10H10N4O2, CAS 535981-37-4
3-[(4-Methoxyphenyl)amino]-1,2,4-triazin-5-ol
CAS 535981-37-4C10H10N4O2
3-[(2-Methoxyphenyl)amino]-1,2,4-triazin-5-ol chemical structure, C10H10N4O2, CAS 535981-29-4
3-[(2-Methoxyphenyl)amino]-1,2,4-triazin-5-ol
CAS 535981-29-4C10H10N4O2
3-[(2-Hydroxyphenyl)amino]-1,2,4-triazin-5(4H)-one chemical structure, C9H8N4O2, CAS 857492-03-6
3-[(2-Hydroxyphenyl)amino]-1,2,4-triazin-5(4H)-one
CAS 857492-03-6C9H8N4O2
3-[(4-Ethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol chemical structure, C12H14N4O, CAS 443097-44-7
3-[(4-Ethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol
CAS 443097-44-7C12H14N4O
3-[(2,3-Dimethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol chemical structure, C12H14N4O, CAS 443097-46-9
3-[(2,3-Dimethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol
CAS 443097-46-9C12H14N4O
3-[(3,4-Dimethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol chemical structure, C12H14N4O, CAS 450375-75-4
3-[(3,4-Dimethylphenyl)amino]-6-methyl-1,2,4-triazin-5-ol
CAS 450375-75-4C12H14N4O