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Murcko scaffold

N-Benzylpyrimidin-2-amine scaffold

298 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
298
With full pages
28
Scaffold SMILES

c1ccc(CNc2ncccn2)cc1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the N-Benzylpyrimidin-2-amine page
Murcko scaffold c1ccc(CNc2ncccn2)cc1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 97 to 144 of 298 chemicals

N-(3-Chlorobenzyl)-4-methylpyrimidin-2-amine chemical structure, C12H12ClN3, CAS 1341869-30-4
N-(3-Chlorobenzyl)-4-methylpyrimidin-2-amine
CAS 1341869-30-4C12H12ClN3
4-Methyl-N-(4-(trifluoromethyl)benzyl)pyrimidin-2-amine chemical structure, C13H12F3N3, CAS 1411273-15-8
4-Methyl-N-(4-(trifluoromethyl)benzyl)pyrimidin-2-amine
CAS 1411273-15-8C13H12F3N3
4-(((4-Methylpyrimidin-2-yl)amino)methyl)benzoic acid chemical structure, C13H13N3O2, CAS 1282240-09-8
4-(((4-Methylpyrimidin-2-yl)amino)methyl)benzoic acid
CAS 1282240-09-8C13H13N3O2
5-Methyl-N-(phenylmethyl)-2-pyrimidinamine chemical structure, C12H13N3, CAS 38373-53-4
5-Methyl-N-(phenylmethyl)-2-pyrimidinamine
CAS 38373-53-4C12H13N3
5-Bromo-N-(3,4-dimethoxybenzyl)pyrimidin-2-amine chemical structure, C13H14BrN3O2, CAS 1273687-35-6
5-Bromo-N-(3,4-dimethoxybenzyl)pyrimidin-2-amine
CAS 1273687-35-6C13H14BrN3O2
N-(2-Aminoethyl)-N-benzyl-5-bromopyrimidin-2-amine chemical structure, C13H15BrN4, CAS 1411360-50-3
N-(2-Aminoethyl)-N-benzyl-5-bromopyrimidin-2-amine
CAS 1411360-50-3C13H15BrN4
N-(2,4-Dimethoxybenzyl)-5-fluoropyrimidin-2-amine chemical structure, C13H14FN3O2, CAS 1354819-21-8
N-(2,4-Dimethoxybenzyl)-5-fluoropyrimidin-2-amine
CAS 1354819-21-8C13H14FN3O2
(5-Bromo-pyrimidin-2-yl)-(2-fluoro-5-trifluoromethyl-benzyl)-amine chemical structure, C12H8BrF4N3, CAS 945847-61-0
(5-Bromo-pyrimidin-2-yl)-(2-fluoro-5-trifluoromethyl-benzyl)-amine
CAS 945847-61-0C12H8BrF4N3
3-Methoxy-5-[[(5-methoxycarbonylpyrimidin-2-yl)amino]methyl]benzoic acid chemical structure, C15H15N3O5, CAS 1552310-77-6
3-Methoxy-5-[[(5-methoxycarbonylpyrimidin-2-yl)amino]methyl]benzoic acid
CAS 1552310-77-6C15H15N3O5
tert-Butyl (2-{[N-(5-cyano-2-{[2-(trifluoromethoxy)benzyl]amino}pyrimidin-4-yl)glycyl]amino}ethyl)carbamate chemical structure, C22H26F3N7O4, CAS 1214727-58-8
tert-Butyl (2-{[N-(5-cyano-2-{[2-(trifluoromethoxy)benzyl]amino}pyrimidin-4-yl)glycyl]amino}ethyl)carbamate
CAS 1214727-58-8C22H26F3N7O4
2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidine-5-carbonitrile chemical structure, C12H11N5O, CAS 920512-26-1
2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidine-5-carbonitrile
CAS 920512-26-1C12H11N5O
2-Amino-5-{[(5-methoxypyrimidin-2-yl)amino]methyl}phenol chemical structure, C12H14N4O2, CAS 920512-25-0
2-Amino-5-{[(5-methoxypyrimidin-2-yl)amino]methyl}phenol
CAS 920512-25-0C12H14N4O2
2-Amino-5-{[(4,6-dimethoxypyrimidin-2-yl)amino]methyl}phenol chemical structure, C13H16N4O3, CAS 920512-29-4
2-Amino-5-{[(4,6-dimethoxypyrimidin-2-yl)amino]methyl}phenol
CAS 920512-29-4C13H16N4O3
2-Amino-5-{[(5-bromopyrimidin-2-yl)amino]methyl}phenol chemical structure, C11H11BrN4O, CAS 920512-23-8
2-Amino-5-{[(5-bromopyrimidin-2-yl)amino]methyl}phenol
CAS 920512-23-8C11H11BrN4O
2-Amino-5-{[(5-chloropyrimidin-2-yl)amino]methyl}phenol chemical structure, C11H11ClN4O, CAS 920512-22-7
2-Amino-5-{[(5-chloropyrimidin-2-yl)amino]methyl}phenol
CAS 920512-22-7C11H11ClN4O
2-Amino-5-{[(pyrimidin-2-yl)amino]methyl}phenol chemical structure, C11H12N4O, CAS 920512-15-8
2-Amino-5-{[(pyrimidin-2-yl)amino]methyl}phenol
CAS 920512-15-8C11H12N4O
2-Amino-5-{[(4-methoxypyrimidin-2-yl)amino]methyl}phenol chemical structure, C12H14N4O2, CAS 920512-20-5
2-Amino-5-{[(4-methoxypyrimidin-2-yl)amino]methyl}phenol
CAS 920512-20-5C12H14N4O2
2-Amino-5-{[(5-methylpyrimidin-2-yl)amino]methyl}phenol chemical structure, C12H14N4O, CAS 920512-21-6
2-Amino-5-{[(5-methylpyrimidin-2-yl)amino]methyl}phenol
CAS 920512-21-6C12H14N4O
2-Amino-5-{[(4-methylpyrimidin-2-yl)amino]methyl}phenol chemical structure, C12H14N4O, CAS 920512-16-9
2-Amino-5-{[(4-methylpyrimidin-2-yl)amino]methyl}phenol
CAS 920512-16-9C12H14N4O
2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidin-5-ol chemical structure, C11H12N4O2, CAS 920512-24-9
2-{[(4-Amino-3-hydroxyphenyl)methyl]amino}pyrimidin-5-ol
CAS 920512-24-9C11H12N4O2
N-[(4-Methoxyphenyl)methyl]-N-methylpyrimidin-2-amine chemical structure, C13H15N3O, CAS 2877632-95-4
N-[(4-Methoxyphenyl)methyl]-N-methylpyrimidin-2-amine
CAS 2877632-95-4C13H15N3O
N-Benzyl-4,6-dichloro-N-methylpyrimidin-2-amine chemical structure, C12H11Cl2N3, CAS 1289029-54-4
N-Benzyl-4,6-dichloro-N-methylpyrimidin-2-amine
CAS 1289029-54-4C12H11Cl2N3
2-Amino-5-{[(4,6-dichloropyrimidin-2-yl)amino]methyl}phenol chemical structure, C11H10Cl2N4O, CAS 920512-27-2
2-Amino-5-{[(4,6-dichloropyrimidin-2-yl)amino]methyl}phenol
CAS 920512-27-2C11H10Cl2N4O
2-Amino-5-{[(4-bromopyrimidin-2-yl)amino]methyl}phenol chemical structure, C11H11BrN4O, CAS 920512-18-1
2-Amino-5-{[(4-bromopyrimidin-2-yl)amino]methyl}phenol
CAS 920512-18-1C11H11BrN4O