Murcko scaffold
N-Benzylpyrimidin-2-amine scaffold
298 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 14
- Chemicals
- 298
- With full pages
- 28
Scaffold SMILES
c1ccc(CNc2ncccn2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 241 to 288 of 298 chemicals
![Ethyl 4-{[(4-methylpyrimidin-2-yl)amino]methyl}benzoate chemical structure, C15H17N3O2, CAS 2639423-09-7](/s/NOXCWDJFRZLLTD-UHFFFAOYSA-N.svg)
Ethyl 4-{[(4-methylpyrimidin-2-yl)amino]methyl}benzoate
CAS 2639423-09-7C15H17N3O2
![Methyl 3-{[(4,6-dimethylpyrimidin-2-yl)amino]methyl}benzoate chemical structure, C15H17N3O2, CAS 2639415-27-1](/s/DIPHVXVRJPVCJX-UHFFFAOYSA-N.svg)
Methyl 3-{[(4,6-dimethylpyrimidin-2-yl)amino]methyl}benzoate
CAS 2639415-27-1C15H17N3O2
![Ethyl 3-{[(4-methylpyrimidin-2-yl)amino]methyl}benzoate chemical structure, C15H17N3O2, CAS 2639412-62-5](/s/JLYSJEOAZNQPSS-UHFFFAOYSA-N.svg)
Ethyl 3-{[(4-methylpyrimidin-2-yl)amino]methyl}benzoate
CAS 2639412-62-5C15H17N3O2
Methyl 2-(benzylamino)-5-chloropyrimidine-4-carboxylate
CAS 2639419-41-1C13H12ClN3O2
tert-Butyl 2-(benzylamino)-5-chloropyrimidine-4-carboxylate
CAS 2639444-93-0C16H18ClN3O2
![tert-Butyl 3-{[(4,6-dimethylpyrimidin-2-yl)amino]methyl}benzoate chemical structure, C18H23N3O2, CAS 2639413-24-2](/s/ZPFYEIUACYPRCC-UHFFFAOYSA-N.svg)
tert-Butyl 3-{[(4,6-dimethylpyrimidin-2-yl)amino]methyl}benzoate
CAS 2639413-24-2C18H23N3O2
![tert-Butyl N-{2-[benzyl(5-bromopyrimidin-2-yl)amino]ethyl}carbamate chemical structure, C18H23BrN4O2, CAS 2680782-66-3](/s/BIPKZTFAPLQSMY-UHFFFAOYSA-N.svg)
tert-Butyl N-{2-[benzyl(5-bromopyrimidin-2-yl)amino]ethyl}carbamate
CAS 2680782-66-3C18H23BrN4O2
![3-{[N-(4,6-Dimethylpyrimidin-2-yl)-2,2,2-trifluoroacetamido]methyl}benzoic acid chemical structure, C16H14F3N3O3, CAS 2680828-53-7](/s/XJRKVKSHNIVGJR-UHFFFAOYSA-N.svg)
3-{[N-(4,6-Dimethylpyrimidin-2-yl)-2,2,2-trifluoroacetamido]methyl}benzoic acid
CAS 2680828-53-7C16H14F3N3O3
![3-{[2,2,2-Trifluoro-N-(4-methylpyrimidin-2-yl)acetamido]methyl}benzoic acid chemical structure, C15H12F3N3O3, CAS 2680903-58-4](/s/ORUVHQBSVAEOSI-UHFFFAOYSA-N.svg)
3-{[2,2,2-Trifluoro-N-(4-methylpyrimidin-2-yl)acetamido]methyl}benzoic acid
CAS 2680903-58-4C15H12F3N3O3
amino}methyl)benzoic acid chemical structure, C18H21N3O4, CAS 2680738-15-0](/s/TYGLDQRFMPODSX-UHFFFAOYSA-N.svg)
3-({[(tert-Butoxy)carbonyl](4-methylpyrimidin-2-yl)amino}methyl)benzoic acid
CAS 2680738-15-0C18H21N3O4
amino}methyl)benzoic acid chemical structure, C19H23N3O4, CAS 2680893-59-6](/s/IHZDAQNRQJSLJG-UHFFFAOYSA-N.svg)
3-({[(tert-Butoxy)carbonyl](4,6-dimethylpyrimidin-2-yl)amino}methyl)benzoic acid
CAS 2680893-59-6C19H23N3O4
![Methyl 2-{[(4-methylphenyl)methyl]amino}pyrimidine-4-carboxylate chemical structure, C14H15N3O2, CAS 2111095-10-2](/s/NLWYYBVONJVRHP-UHFFFAOYSA-N.svg)
Methyl 2-{[(4-methylphenyl)methyl]amino}pyrimidine-4-carboxylate
CAS 2111095-10-2C14H15N3O2
![Methyl 2-{[(4-fluorophenyl)methyl]amino}pyrimidine-4-carboxylate chemical structure, C13H12FN3O2, CAS 2105653-84-5](/s/SXSPBXUISXKTKE-UHFFFAOYSA-N.svg)
Methyl 2-{[(4-fluorophenyl)methyl]amino}pyrimidine-4-carboxylate
CAS 2105653-84-5C13H12FN3O2
![Methyl 2-{[(4-chlorophenyl)methyl]amino}pyrimidine-4-carboxylate chemical structure, C13H12ClN3O2, CAS 2110094-71-6](/s/XSRGQLOLNLDHDR-UHFFFAOYSA-N.svg)
Methyl 2-{[(4-chlorophenyl)methyl]amino}pyrimidine-4-carboxylate
CAS 2110094-71-6C13H12ClN3O2
![Methyl 2-{[(2-chlorophenyl)methyl]amino}pyrimidine-4-carboxylate chemical structure, C13H12ClN3O2, CAS 2109945-21-1](/s/VMKYUVBFAUEWDY-UHFFFAOYSA-N.svg)
Methyl 2-{[(2-chlorophenyl)methyl]amino}pyrimidine-4-carboxylate
CAS 2109945-21-1C13H12ClN3O2
![Methyl 2-[(1-phenylethyl)amino]pyrimidine-4-carboxylate chemical structure, C14H15N3O2, CAS 2443966-01-4](/s/FEUDPXFXNKEAHL-UHFFFAOYSA-N.svg)
Methyl 2-[(1-phenylethyl)amino]pyrimidine-4-carboxylate
CAS 2443966-01-4C14H15N3O2
![Methyl 2-[benzyl(methyl)amino]pyrimidine-4-carboxylate chemical structure, C14H15N3O2, CAS 2437032-48-7](/s/SBRBEVHKFBFMTA-UHFFFAOYSA-N.svg)
Methyl 2-[benzyl(methyl)amino]pyrimidine-4-carboxylate
CAS 2437032-48-7C14H15N3O2
![Methyl 2-{[(2-fluorophenyl)methyl]amino}pyrimidine-4-carboxylate chemical structure, C13H12FN3O2, CAS 2443966-11-6](/s/WQWXHEPDMVJHGA-UHFFFAOYSA-N.svg)
Methyl 2-{[(2-fluorophenyl)methyl]amino}pyrimidine-4-carboxylate
CAS 2443966-11-6C13H12FN3O2
Ethyl 2-(benzylamino)pyrimidine-4-carboxylate
CAS 2106828-37-7C14H15N3O2
![(2-{[(4-Methoxyphenyl)methyl]amino}pyrimidin-4-yl)methanol chemical structure, C13H15N3O2, CAS 2436594-25-9](/s/VUZDEWMBXBKAFN-UHFFFAOYSA-N.svg)
(2-{[(4-Methoxyphenyl)methyl]amino}pyrimidin-4-yl)methanol
CAS 2436594-25-9C13H15N3O2
![(2-{[(4-Methylphenyl)methyl]amino}pyrimidin-4-yl)methanol chemical structure, C13H15N3O, CAS 2444613-67-4](/s/VWPKZEIDTFWRHB-UHFFFAOYSA-N.svg)
(2-{[(4-Methylphenyl)methyl]amino}pyrimidin-4-yl)methanol
CAS 2444613-67-4C13H15N3O
![(2-{[(4-Fluorophenyl)methyl]amino}pyrimidin-4-yl)methanol chemical structure, C12H12FN3O, CAS 2436383-00-3](/s/ZYAABHIPAXWVIM-UHFFFAOYSA-N.svg)
(2-{[(4-Fluorophenyl)methyl]amino}pyrimidin-4-yl)methanol
CAS 2436383-00-3C12H12FN3O
![(2-{[(4-Chlorophenyl)methyl]amino}pyrimidin-4-yl)methanol chemical structure, C12H12ClN3O, CAS 2436594-39-5](/s/KOOYTKQOBALKKX-UHFFFAOYSA-N.svg)
(2-{[(4-Chlorophenyl)methyl]amino}pyrimidin-4-yl)methanol
CAS 2436594-39-5C12H12ClN3O
![(2-{[(2-Methoxyphenyl)methyl]amino}pyrimidin-4-yl)methanol chemical structure, C13H15N3O2, CAS 2438928-98-2](/s/CKSUNYCBHOCBPF-UHFFFAOYSA-N.svg)
(2-{[(2-Methoxyphenyl)methyl]amino}pyrimidin-4-yl)methanol
CAS 2438928-98-2C13H15N3O2
- (2-{[(2-Chlorophenyl)methyl]amino}pyrimidin-4-yl)methanol2438044-83-6C12H12ClN3O
- (2-{[(3-Methoxyphenyl)methyl]amino}pyrimidin-4-yl)methanol2436522-84-6C13H15N3O2
- {2-[(1-Phenylethyl)amino]pyrimidin-4-yl}methanol2444613-79-8C13H15N3O
- {2-[Benzyl(ethyl)amino]pyrimidin-4-yl}methanol2281115-02-2C14H17N3O
- {2-[Benzyl(methyl)amino]pyrimidin-4-yl}methanol2284879-55-4C13H15N3O
- (2-{[(2-Fluorophenyl)methyl]amino}pyrimidin-4-yl)methanol2439099-20-2C12H12FN3O
- [2-({[3-(Trifluoromethyl)phenyl]methyl}amino)pyrimidin-4-yl]methanol2436380-45-7C13H12F3N3O
- 4-(Aminomethyl)-N-benzylpyrimidin-2-amine2107086-44-0C12H14N4
- 4-(Aminomethyl)-N-[(4-methoxyphenyl)methyl]pyrimidin-2-amine2110802-85-0C13H16N4O
- 4-(Aminomethyl)-N-[(4-methylphenyl)methyl]pyrimidin-2-amine2107511-75-9C13H16N4
- 4-(Aminomethyl)-N-[(4-fluorophenyl)methyl]pyrimidin-2-amine2103870-86-4C12H13FN4
- 4-(Aminomethyl)-N-[(4-chlorophenyl)methyl]pyrimidin-2-amine2106370-87-8C12H13ClN4
- 4-(Aminomethyl)-N-[(2-methoxyphenyl)methyl]pyrimidin-2-amine2446938-56-1C13H16N4O
- 4-(Aminomethyl)-N-[(2-chlorophenyl)methyl]pyrimidin-2-amine2106372-09-0C12H13ClN4
- 4-(Aminomethyl)-N-[(3-methoxyphenyl)methyl]pyrimidin-2-amine2106371-72-4C13H16N4O
- 4-(Aminomethyl)-N-(1-phenylethyl)pyrimidin-2-amine2436594-50-0C13H16N4
- 4-(Aminomethyl)-N-[(2-fluorophenyl)methyl]pyrimidin-2-amine2445478-85-1C12H13FN4
- 4-(Aminomethyl)-N-[(2,4-dimethoxyphenyl)methyl]pyrimidin-2-amine2446938-92-5C14H18N4O2
- 4-(Aminomethyl)-N-{[3-(trifluoromethyl)phenyl]methyl}pyrimidin-2-amine2438929-00-9C13H13F3N4
- Methyl 4-{[(5-fluoropyrimidin-2-yl)amino]methyl}benzoate2749728-87-6C13H12FN3O2
- N-[(2,6-Difluorophenyl)methyl]-5-fluoropyrimidin-2-amine2327351-12-0C11H8F3N3
- N-[(2,6-Difluorophenyl)methyl]-5-methylpyrimidin-2-amine2325085-02-5C12H11F2N3
- Hdac6-IN-212920929-76-4C14H13F2N5O2
- 5-Fluoro-N-{[2-(trifluoromethoxy)phenyl]methyl}pyrimidin-2-amine3054414-52-4C12H9F4N3O
Related scaffolds
Same ring framework with different atoms or bond orders
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C(=Cc1ccccc1)c1ccccc1279 chemicals
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O=C(Cc1ccccc1)c1ccccc1137 chemicals
O=C(Nc1ccccn1)c1ccccc1120 chemicals